CAS: 625-22-9; Di-N-Butylsulfate

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5867-98-1 598-05-0 626-85-7

上下游产品

CAS号626-85-7 亚硫酸二正丁酯 | CAS号102-85-2 亚磷酸三丁酯 | CAS号763-23-5 1-chlorosulfony... | CAS号688-74-4 硼酸三丁酯 | CAS号71-36-3 正丁醇 | CAS号142-96-1 正丁醚 | CAS号544-40-1 二丁基硫醚 | CAS号401788-98-5 1-丁基-3-甲基咪唑硫酸甲酯 | CAS号583-03-9 1-苯基-1-戊醇 | CAS号104-51-8 丁基苯 | CAS号628-71-7 1-庚炔 | CAS号2384-90-9 1,2-Heptadiene | CAS号101-57-5 二苯基胺-4-磺酸 | CAS号15507-13-8 硫酸单丁酯 | CAS号1191-47-5 二丁基镁 | CAS号102526-51-2 sulfuric acid m...

📜亚硫酸二正丁酯置于磺酰氯体系中,化学反应生成 硫酸二丁酯
参考文献:Suter; Gerhart,Organic Syntheses,Collective
标题:Suter; Gerhart,Organic Syntheses,Collective

专利信息

专利号:US-2024199680-A1
优先权日:2021-04-02
标 题:Synthesis of fluorinated cyclic dinucleotides
发明人：AN CHIHUI; FIER PATRICK S; HIRAGA KAORI; LIU ZHIJIAN; MARSHALL NICHOLAS M; MCINTOSH JOHN; MILLER STEVEN P; MOORE JEFFREY C; MURPHY GRANT S; OBLIGACION JENNIFER V; PAN WEILAN; PENG FENG; SALEHI MARZIJARANI NASTARAN; WINSTON MATTHEW S
权利人:MERCK SHARP & DOHME LLC
摘要:The present invention relates to efficient processes useful in the preparation of fluorinated cyclic dinucleosides, such as [P(R)]-2′-deoxy-2′-fluoro-5′-O—[(R)-hydroxymercaptophosphinyl]-P-thio-β-D-arabino-adenylyl-(3′→5′)-3′-deoxy-3′-fluoroguanosine cyclic nucleotide, which is also known as (2R,5R,7R,8S,10R,12aR,14R,15S,15aR,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-15,16-difluoro-2, 10-bis(sulfanyl)octahydro-2H,10H, 12H-2λ 5 ,10λ 5 -5,8-methanofuro[3,2-1][1, 3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.

专利号:US-9493461-B2
优先权日:2013-02-07
标 题 :Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis C
发明人：DAI XING; LIU HONG; PALANI ANANDAN; HE SHUWEN; LAI ZHONG; NARGUND RAVI; MARCANTONIO KAREN; XIAO DONG; BROCKUNIER LINDA L; ZORN NICOLAS; DANG QUN; PENG XUANJIA; LI PENG
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula I that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-9573939-B2
优先权日:2011-09-08
标题:Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
发明人：MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; DAI XING; LIU HONG; HE SHUWEN; DANG QUN
权利人:MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; DAI XING; LIU HONG; HE SHUWEN; DANG QUN; MERCK SHARP & DOHME; MSD ITALIA SRL
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-2004267028-A1
优先权日:2001-09-24
标题 :Preparation and use of pyrrole derivatives for treating obesity
发明人：SMITH ROGER A; KLUENDER HAROLD C; SU NING; LAVOIE RICO C; FAN JIANMEI
权利人:SMITH ROGER A; KLUENDER HAROLD C; SU NING; LAVOIE RICO C; FAN JIANMEI
摘要:This invention relates to pyrrole derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.

专利号:US-2016130259-A1
优先权日:2013-06-24
标题 :Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
发明人：LIU HONG; DAI XING; PALANI ANANDAN; HE SHUWEN; NARGUND RAVI; XIAO DONG; DANG QUN; PENG XUANJIA; LI PENG
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula I that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-2024140920-A1
优先权日:2021-02-11
标 题:Synthesis of uridine
发明人：BENKOVICS TAMAS; FRYSZKOWSKA ANNA; HUFFMAN MARK A; ITOH TETSUJI; MALONEY KEVIN M; MCINTOSH JOHN; MURPHY GRANT S
权利人:MERCK SHARP & DOHME LLC
摘要:The present invention relates to efficient synthetic processes useful in the preparation of uridine, which is useful in the production of nucleosides and nucleotides that may be active as antiviral agents, as well as compositions and methods thereof.