📜Boc-Dl-天冬氨酸,苯甲醇 反应生成 Boc-D-天冬氨酸 参考文献:Cantacuzene,D.;Pascal,F.;Guerreiro,C.,Tetrahedron,43,(1987) N 8,1823-1826 标题:Cantacuzene,D.;Pascal,F.;Guerreiro,C.,Tetrahedron,43,(1987) N 8,1823-1826
专利号:US-6359144-B1 优先权日:1997-02-04 标 题 :Combinatorial libraries of bicyclic guanidine derivatives and compounds therein 发明人:OSTRESH JOHN M; MEYER JEAN-PHILIPPE; DOOLEY COLETTE T; BLONDELLE SYLVIE E; SCHONER CHRISTA C; HOUGHTEN RICHARD A 权利人:LION BIOSCIENCE AG 摘要:The invention provides a rapid approach for combinatorial synthesis and screening of combinatorial libraries of bicyclic guanidine compounds. The present invention further provides the compounds made by the combinatorial synthesis and individually as well as methods of using the same.
专利号:US-2022185846-A1 优先权日:2019-03-28 标 题:Methods for synthesizing beta-homoamino acids 发明人:MANTHATI SURESH KUMAR; BHANDARI ASHOK; MASJEDIZADEH MOHAMMAD REZA 权利人:PROTAGONIST THERAPEUTICS INC 摘要:Methods of making β-homoamino acids as intermediate for synthesis of peptide monmer and dimer α4β7-antagonists are disclosed. The disclosed methods include solid phase and solution phase methods.
专利号:CN-103159638-A 优先权日:2013-03-15 标 题:Synthesis of N-methyl-D-aspartic acid
专利号:US-7179794-B2 优先权日:1998-06-08 标题 :Multivalent macrolide antibiotics 发明人:GRIFFIN JOHN H; PACE JOHN L 权利人:THERAVANCE INC 摘要:Disclosed are multibinding compounds which include macrolide antibiotics, aminoglycosides, lincosamides, oxazolidinones, streptoramins, tetracycline and/or other compounds which bind to bacterial ribosomal RNA and/or to one or more proteins involved in ribosomal protein synthesis in the bacterium, which are useful in treating bacterial infections. The compounds adversely affect protein expression and have an antibacterial effect. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is macrolide antibiotic, aminoglycoside, lincosamide, oxazolidinone, streptogramin, tetracycline or other compound which binds to bacterial ribosomal RNA and/or one or more proteins involved in ribosomal protein synthesis in the bacterium.
[参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
合成参考文献
参考文献:10.1163/156856789x00096 摘要:Rhofir C, Vocelle D, Sandorfy C. Ftir study of the protonation of a retinyl schiff base in chloroform/methanol mixtures. Research on Chemical Intermediates. 1989 Jun;12(2):131–9. doi: 10.1163/156856789x00096.