CAS: 621-33-0; 3-Ethoxyaniline

该化合物是一种有机化合物,其特点是,苯环上有一个与氨基氨基基氨(-NH2)相比具有元位的乙氧基组(-OCH2CH3),该化合物具有C9H13NO分子式,具有反映其结构的分子重量,通常无色可粉黄黄色液体或固态,视温度和纯度而定. 3-乙氧苯胺在有机溶剂中可溶解,并由于氨基化合物组的存在而在水中表现出中等溶解性,氨基混合物可以进行氢结交.该化合物用于各种用途,包括作为染料,药物和农用化学物合成的中间体.必须谨慎处理该物质,因为它可能构成健康风险,包括皮肤和眼刺激,如果摄入或吸入,则具有潜在毒性.在与该化学品合作时,应注意适当的安全措施.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号621-52-3 3-硝基苯乙醚 | CAS号588-02-3 3,3'-Diethoxyaz... | CAS号55792-09-1 2-piperidin-1-i... | CAS号621-42-1 3'-羟基乙酰苯胺 | CAS号591-33-3 3-乙氧基乙酰苯胺 | CAS号64-17-5 乙醇 | CAS号7647-01-0 盐酸 | CAS号90434-59-6 3-乙氧基苯基肼 | CAS号361162-95-0 6-氨基-4-(3-氯-4氟苯... | CAS号1864-91-1 3-ethoxy-N,N-di... | CAS号214476-07-0 7-乙氧基-4-羟基喹啉-3-甲腈 | CAS号86704-82-7 3-乙氧基苯硫酚 | CAS号93071-76-2 3-乙氧苯基甲胺 | CAS号747411-11-6 3-乙氧基硫代苯甲酰胺 | CAS号55792-32-0 3-甲氧基异氰酸苯酯 | CAS号591-33-3 3-乙氧基乙酰苯胺 | CAS号13140-68-6 1-(3-ethoxyphen... | CAS号13142-86-4 M-ETHOXYPHENYLUREA

合成工艺路线路线简述

    间硝基苯酚置于potassium Carbonate,溶剂黄146体系中,用 乙醇,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 0.33H,反应生成 间氨基苯乙醚
    参考文献:[cp*rhcl2]2-Catalyzed Alkyne Hydroamination To 1,2-Dihydroquinolines
    标题:[cp*rhcl2]2-Catalyzed Alkyne Hydroamination To 1,2-Dihydroquinolines
    摘要:[cp*rhcl2](2) Catalyzes The Formation Of 1,2-Dihydroquinolines From The Reaction Of Two Terminal Alkynes And An Aniline. This Reaction Is Believed To Proceed Via An Alkyne Hydroamination Followed By An Alkyne Insertion..
    DOI:10.1021/om501253V

    海关参考信息

    专利信息


    专利号:US-4871873-A
    优先权日:1988-03-18
    标 题:Process for synthesis of arylglyoxal arylimines
    发明人:DESMOND RICHARD; MILLS SANDER G; VOLANTE RALPH P; SHINKAI ICHIRO
    权利人:MERCK & CO INC
    摘要:A process for producing arylglyoxal arylimine intermediates, by the DMSO/HBr oxidation of arylmethylketones. The imine compounds are intermediates in the synthesis of carbapenem antibiotics, i.e. imipenem.

    专利号:US-4719053-A
    优先权日:1980-08-01
    标题 :Beta-chloroethylsulfonylmethyl-benzoic halides as intermediates
    发明人:SCHLAEFER LUDWIG; HAEHNLE REINHARD
    权利人:HOECHST AG
    摘要:New beta -chloroethylsuflonylmethyl-benzoic acid halides which can serve as fibre-reactive anchors for thesynthesis of novel organic, water-soluble compounds, preferably dyestuffs, having fibre-reactive and fibre-finishing properties, such as preferably dyestuff properties, and containing, as a fibre-reactive group, one or two beta -chloroethylsufonylmethylbenzoic acid amide groups. For the synthesis of these novel fibre-finishing compounds, said new beta -chloroethylsulfonylmethyl-benzoic acid halide compounds are reacted with an organic, water-soluble compound having fibre-finishing properties and continuing one or two amino groups. Also precursors of the fibre-finishing, fibre-reactive compounds, containing said beta -chloroethylsulfonylmethyl-benzxoic acid amid grouping, can be employed for their synthesis. The novel fibre-finishing compounds can be applied onto suitable fibre materials, such as especially cellulose fibre material and natural or synthetic polyamide fibre materials, and fixed on these fibre materials in a manner similar to application and fixation methods usual in the technique for fibre-reactive compounds. The fibre-finished material, such as dyed material, shows very good wet fastnesses.

    专利号:US-2022281888-A1
    优先权日:2019-09-25
    标题:Bicyclic carboxylates as modulators of transporters and uses thereof
    发明人:SANDANAYAKA VINCENT; GORECZNY GREGORY
    权利人:NIROGY THERAPEUTICS INC
    摘要:The present invention generally relates to the field of transporter modulators, e.g., monocarboxylate transporter inhibitors, and more particularly to new bicyclic enone carboxylate compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with monocarboxylate transporter activity such as in treating cancer and other neoplastic disorders, tissue and organ transplant rejection.

    专利号:US-6531470-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6562844-B2
    优先权日:1998-01-23
    标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6417195-B1
    优先权日:1999-02-22
    标题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
    发明人:LEBL MICHAL
    权利人:LION BIOSCIENCE AG
    摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compounds.
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    合成参考文献


    摘要:Hagen, T. J.; Helgren, T. R., Science of Synthesis Knowledge Updates, (2015) 2, 155.
    摘要:N. F. Hall and M. R. Sprinkle. J. Am. Chem. Soc. 54, 3469 (1932).
    摘要:Kleemann A., Kutscher B., Reichert D., Bossart M., Pharmaceutical Substances, Thieme [Online], Stuttgart, (2025).
    参考文献:10.1107/s1600536810022427
    摘要:Aziz-Ur-Rehman, Siddiqa A, Akkurt M, Abbasi MA, Jahangir M, Khan IU. N-(3-Eth-oxy-phen-yl)-4-methyl-benzene-sulfonamide. Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 16;66(Pt 7):o1682.
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