CAS: 5813-89-8; 2-Thiophenecarboxamide

上下游产品

thiophene carbamic chloride thiophene-2-carbaldehyde thiophene-2-carbonitrile 2-thiophenylcarboxylic acid 4-chloromethyl-2-(thien-2-yl)oxazole N-(thiophene-2-ylcarbonyl)-N'-(phenyl)thiourea thiophene-2-carbonitrile

📜2-噻吩甲酸置于fac-Tris(2-Phenylpyridinato-N,C2')Iridium(Iii),Dipotassium Hydrogenphosphate,硼烷铵络合物,二碳酸二叔丁酯,Magnesium Chloride体系中,用 乙腈 作为反应溶剂,化学反应 36.0H,以62%的收率获得产物2-噻吩甲酰胺
参考文献:可见光介导的从羧酸和胺-硼烷的酰胺合成
标题:可见光介导的从羧酸和胺-硼烷的酰胺合成
摘要:在此,描述了使用容易获得的胺-硼烷和羧酸的光催化脱氧酰胺化方案.这种方法的特点是条件温和,收率中等至非常好,易于放大,并具有多达62个带有各种取代基的官能化酰胺实例.该方法在几种药物分子的后期功能化中的应用也证明了该方法的综合耐用性.
DOI:10.1039/d1Gc01157J

专利信息

专利号:US-11891384-B2
优先权日:2017-01-04
标题:Process for the preparation of Rivaroxaban involving novel intermediate
发明人：SATHE DHANANJAY G; DAS ARIJIT; Raikar Sanjay; SURVE YASHWANT S; PANDIT BHUSHAN S
权利人:UNICHEM LAB LTD
摘要:The present invention relates to the novel key intermediate, 4-{4-[(SS)-(Aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]-phenyl}-morpholin-3-one perchlorate, m the synthesis of rivaroxaban. The invention further relates to the crystalline form of novel intermediate, the process to prepare the novel intermediate and method of preparing rivaroxaban using this novel intermediate. The invention provides an improved and efficient process for preparation of Rivaroxaban.

专利号:WO-2013046211-A1
优先权日:2011-09-27
标 题 :Processes for the preparation of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl) phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophene-carboxamide and intermediates thereof
发明人：MOHAN RAO DODDA; KRISHNA REDDY PINGILI; VENKAT REDDY BUTHUKURI
权利人:SYMED LABS LTD; MOHAN RAO DODDA; KRISHNA REDDY PINGILI; VENKAT REDDY BUTHUKURI
摘要:TThe present invention provides processes for the preparation of 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophene-carboxamide (I) and intermediates thereof. Also provides novel intermediates and their use in the synthesis of oxazolidine derivatives.

专利号:US-9598418-B2
优先权日:2012-12-31
标 题:Substituted phthalazin-1 (2H)-one derivatives as selective inhibitors of poly (ADP-ribose) polymerase-1
发明人：SRIVASTAVA BRIJESH K; DESAI RANJIT C; PATEL PANKAJ R
权利人:CADILA HEALTHCARE LTD
摘要:The present invention relates to novel compounds of general formula (I), their stereoisomers, regioisomers, tautomeric forms and novel intermediates involved in their synthesis, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. The present invention also relates to a process of preparing novel compounds of general formula (I), their stereoisomers, regioisomers, their tautomeric forms, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutical compositions containing them, and novel intermediates involved in their synthesis.

专利号:CN-115961298-B
优先权日:2022-12-31
标 题 :Electrochemical-mediated synthesis of 2, 3-dialkoxyl substituted indoline compound from vinylaniline and alcohol, synthesis method and application

专利号:CN-116791111-A
优先权日:2022-12-31
标题 :An electrochemical synthesis of alkoxybenzoxazine compounds, synthesis methods and applications

专利号:US-7179918-B2
优先权日:2001-06-11
标 题:HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis
发明人：CANAN KOCH STACIE S; ALEXANDER THERESE N; BURKE BENJAMIN J; JEWELL TANYA M; KUCERA DAVID J; LINTON MARIA ANGELICA; MITCHELL JR LENNERT J; REICH SIEGFRIED H; SKALITZKY DONALD J; TATLOCK JOHN H; VARNEY MICHAEL D; VIRGIL SCOTT C; WEBBER STEPHEN E; WORLAND STEPHEN T; BARVIAN MARK; BOLTON GARY; BOYER JR FREDERICK EARL; MACHAK JEFFREY J; HOLLER TOD; MURPHY SEAN T; MELNICK MICHAEL; JOSYULA VARA PRASAD
权利人:AGOURON PHARMA
摘要:Compounds of the formula: n nwhere the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.