CAS: 50868-72-9; 5-Methoxy-2-Methylaniline

该化合物是一种芳香的衍生物,其特征是五方有甲氧基组和二方有甲基,该化合物是有机合成的多用途中间体,特别是在染料,药品和农用化学品生产方面,其结构特征提高了电益替代和混合反应的回动性,使其对构建复杂的分子框架很有价值.

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上下游产品

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合成工艺路线路线简述

    📜1-(5-Iodo-2-Methylphenyl)-2,5-Dimethyl-1H-Pyrrole置于盐酸羟胺,Sodium Methylate,三乙胺,Copper(L) Chloride体系中,用 乙醇,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 20.0H,反应生成 5-甲氧基-2-甲基苯胺
    参考文献:2,5-Dimethylpyrrole Protection Facilitates Copper(I)-Mediated Methoxylations Of Aryl Iodides In The Presence Of Anilines
    标题:2,5-Dimethylpyrrole Protection Facilitates Copper(I)-Mediated Methoxylations Of Aryl Iodides In The Presence Of Anilines
    摘要:
    DOI:10.1055/s-1998-2189

    海关参考信息

    专利信息


    专利号:US-2023104311-A1
    优先权日:2020-02-17
    标题:Novel 6-substituted 7-deazapurines and corresponding nucleosides as medicaments
    发明人:HERDEWIJN PIET; GROAZ ELISABETTA; QINGFENG LI
    权利人:UNIV LEUVEN KATH
    摘要:The present invention relates to the synthesis of 6-substituted 7-deazapurines and their corresponding nucleosides by coupling aryl or alkyl Grignard reagents with halogenated purine nucleosides in the presence of iron or an iron/copper mixture such as Fe(acac)3/CuI. The present invention also relates to pharmaceutical compositions comprising said compounds and the use of said pharmaceutical compositions to treat or prevent viral infections.

    专利号:WO-2015100145-A1
    优先权日:2013-12-23
    标题:Synthesis of a macrocyclic hcv ns3 inhibiting tripeptide

    专利号:US-8129411-B2
    优先权日:2005-12-30
    标题:Organic compounds
    发明人:EHARA TAKERU; GROSCHE PHILIPP; IRIE OSAMU; IWAKI YUKI; KANAZAWA TAKANORI; KAWAKAMI SHIMPEI; KONISHI KAZUHIDE; MOGI MUNETO; SUZUKI MASAKI; YOKOKAWA FUMIAKI
    权利人:EHARA TAKERU; GROSCHE PHILIPP; IRIE OSAMU; IWAKI YUKI; KANAZAWA TAKANORI; KAWAKAMI SHIMPEI; KONISHI KAZUHIDE; MOGI MUNETO; SUZUKI MASAKI; YOKOKAWA FUMIAKI; NOVARTIS AG
    摘要:The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,5-substituted piperidine compound, a method for the manufacture of a 3,5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. n The compounds have the formula I′ n nwherein R1, R2, T, R3 and R4 are as defined in the specification.

    专利号:CN-116768739-A
    优先权日:2023-06-21
    标 题 :Chemical synthesis method of 4-chloro-5-methoxy-2-methylaniline

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    合成参考文献


    摘要:Hou, W.; Yang, G.; Xu, H., Science of Synthesis: DNA-Encoded Libraries, (2024) nan, 183.
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