CAS: 490-03-9; 2-Cyclohexen-1-One, 2-Hydroxy-3-Methyl-6-(1-Methylethyl)-

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上下游产品

胡椒酮 Piperitone 89-81-6
2-Hydroxy-3-Methyl-2-Cyclohexen-1-One 3400-78-0
2-Hydroxy-3-Isopropyl-2-Cyclohexenone 55277-49-1
3-Isopropyl-6-Methylcyclohex-2-Enon-2-Yl Bromoacetate 196618-45-8

合成工艺路线路线简述

    📜5-甲基-2-异丙基环己酮置于三氯化铁体系中,用 溶剂黄146 作为反应溶剂,化学反应 1.5H,以0.75 G的收率获得产物2-羟基-6-(异丙基)-3-甲基环己-2-烯-1-酮
    参考文献:Wahidullah,Solimabi; Paknikar,S. K.,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1987,Vol. 26,# 1-12,P. 880-881
    标题:Wahidullah,Solimabi; Paknikar,S. K.,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1987,Vol. 26,# 1-12,P. 880-881

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    专利信息


    专利号:US-5210314-A
    优先权日:1990-05-03
    标题:Preparation of canthaxanthin and astaxanthin
    发明人:ERNST HANSGEORG; PAUST JOACHIM; HOFFMANN WERNER
    权利人:BASF AG
    摘要:A process for preparing canthaxanthin (Ia) and astaxanthin (Ib) of the formula I ##STR1## n where R is H (a) or OH (b), comprises reacting a tertiary alcohol of the formula II ##STR2## n where R is H (a) or OH (b), with trifluoroacetic acid, reacting the resulting novel trifluoroacetate of the formula III ##STR3## n with triphenylphosphine, and reacting the resulting novel triphenylphosphonium trifluoroacetate of the formula IV ##STR4## n with 2,7-dimethyl-2,4,6-octatriene-1,8-dial under the conditions of a Wittig synthesis. The present invention also relates to the novel trifluoroacetates of the formula III and the corresponding triphenylphosphonium trifluoroacetates of the formula IV.

    专利号:US-8969395-B2
    优先权日:2009-05-20
    标题 :Triterpenoid derivatives useful as antiproliferative agents
    发明人:RIBEIRO SALVADOR JORGE ANTONIO; MENDES DOS SANTOS RITA CATARINA; CASCANTE SERRATOSA MARTA
    权利人:RIBEIRO SALVADOR JORGE ANTONIO; MENDES DOS SANTOS RITA CATARINA; CASCANTE SERRATOSA MARTA; UNIV DE COIMBRA
    摘要:Formula (I) and (II). The present invention relates to the use of a new lupane derivative of general formula (I) or (II), or a pharmaceutically acceptable salt, crystal form, complex, hydrate, or hydrolysable ester thereof, for preventing and/or inhibiting tumor growth and for treating cancer and other proliferative diseases, more particularly for treating leukemia, liver, cervical, colon and prostate cancer. The present invention also relates to the synthesis of these compounds and to pharmaceutical compositions which contain them.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/bf02976628
    摘要:Suh J, Jo Y, Kim ND, Bae SJ, Jung JH, Im KS. Cytotoxic constituents of the leaves of Ixeris sonchifolia. Arch Pharm Res. 2002 Jun;25(3):289–92. doi: 10.1007/bf02976628.
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