CAS: 4897-84-1; Methyl 4-Bromobutanoate

相似化合物

2623-87-2 33036-62-3 5454-83-1

上下游产品

CAS号107903-02-6 methyl 4-aminoo... | CAS号111479-52-8 dimethyl 2-(ben... | CAS号33036-62-3 4-溴-1-丁醇 | CAS号71-36-3 正丁醇 | CAS号96-48-0 γ-丁内酯 | CAS号74-83-9 溴甲烷 | CAS号623-43-8 巴豆酸甲酯 | CAS号3724-55-8 3-丁烯酸甲酯 | CAS号88-75-5 邻硝基苯酚

γ-丁内酯置于氢溴酸体系中,化学反应生成 4-溴丁酸甲酯
参考文献:Spiro[4.5]Decanone-1
标题:Spiro[4.5]Decanone-1
摘要:
DOI:10.1021/jo50003A012

专利信息

专利号:US-7429658-B2
优先权日:2003-09-11
标题 :Synthesis of protected pyrrolobenzodiazepines
发明人：HOWARD PHILIP; MASTERSON LUKE
权利人:SPIROGEN LTD
摘要:A method of synthesis of a N-10 protected PBD compound of formula (I): n nvia an intermediate of formula (II) or formula (V):

专利号:US-5679773-A
优先权日:1995-01-17
标题 :Reagants and methods for immobilized polymer synthesis and display
发明人：HOLMES CHRISTOPHER P
权利人:AFFYMAX TECH NV
摘要:Compounds and methods for solid phase synthesis of organic molecules including peptides, oligonucleotides, benzodiazepines, beta -turn mimetics, and prostaglandins. The present invention provides new reagents in the form of linking groups and resins and substrates having attached linking groups which are useful in solid phase synthesis of high density arrays of organic molecules. The invention also provides methods which increase yields of various organic synthesis strategies.

专利号:US-2025091989-A1
优先权日:2023-09-19
标 题 :Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-10730906-B2
优先权日:2002-08-01
标题:Multi-step synthesis of templated molecules
发明人：PEDERSEN HENRIK
权利人:PEDERSEN HENRIK; NUEVOLUTIONS AS
摘要:Disclosed is a method for the manufacture of a library of complexes. The complexes comprise templated molecules attached to the template which directed the synthesis thereof. The templated molecules are produced in a step-by-step fashion which provides for a high local concentration of reactive groups involved in the formation of connections between the individual components of the template molecule.

专利号:US-6753449-B2
优先权日:2001-10-09
标题 :Cleavable linker for solid phase synthesis
发明人：GUO MAOJUN
权利人:ARQULE INC
摘要:Cleavable alkene-containing linkers and supports useful for the solid phase synthesis of chemical compounds, and combinatorial libraries of compounds, are disclosed. Also disclosed are methods of making and using the linkers and supports.

专利号:US-2025222120-A1
优先权日:2024-01-09
标题 :Synthesis of novel small molecule carm1 degraders, compounds formed thereby, and pharmaceutical compositions containing them
发明人：TANG WEIPING; XU WEI; XIE HAIBO; BACABAC MEGAN
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Provided herein are CARM1 PROTACs comprising a binding molecule of CARM1 with an optimized linker attached to an E3 ubiquitin ligase ligand that recruits the E3 ubiquitin ligase to CARM1. The PROTACs find use, e.g., for selectively targeted degradation of CARM1 protein in cancer cells. Also provided herein are compositions comprising the PROTACs, as well as methods of using the PROTACs.