CAS: 456-22-4; 4-Fluorobenzoic Acid

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CAS号124-38-9 二氧化碳 | CAS号225916-39-2 4-氟苯硼酸新戊二醇酯 | CAS号53458-16-5 1,2-双(4-氟苯基)-2-羟基乙酮 | CAS号352-32-9 对氟甲苯 | CAS号459-56-3 对氟苯甲醇 | CAS号460-00-4 对氟溴苯 | CAS号352-11-4 对氟氯苄 | CAS号459-57-4 对氟苯甲醛 | CAS号201230-82-2 carbon monoxide | CAS号403-41-8 1-(4-氟苯基)乙醇 | CAS号455-86-7 3,4-二氟苯甲酸 | CAS号403-15-6 4-氟-3-甲基-苯甲酸 | CAS号321-21-1 4-氟-2-甲基苯甲酸 | CAS号64436-59-5 1-Propanone, 2,... | CAS号403-18-9 3-碘-4-氟苯甲酸 | CAS号453-71-4 4-氟-3-硝基苯甲酸 | CAS号350-46-9 对氟硝基苯 | CAS号329-59-9 4-氟-3-硝基苯甲酸甲酯 | CAS号327-95-7 4-氟间苯二甲酸 | CAS号345-29-9 4-氟水杨酸

对氨基苯甲酸置于三氟化硼乙醚,1-氟-3,3-二甲基-1,2-苯并碘氧杂戊环体系中,用 乙醇,氯苯 作为反应溶剂,化学反应 37.0H,反应生成 对氟苯甲酸
参考文献:轻度条件下高价碘(iii)催化的balz-schiemann氟化
标题:轻度条件下高价碘(iii)催化的balz-schiemann氟化
摘要:描述了前所未有的高价碘(iii)催化的balz-Schiemann反应.在存在高价碘化合物的情况下,氟化反应会在温和的条件下(25-60oc)进行,并且具有广泛的底物范围和非常好的官能团相容性.
DOI:10.1002/anie.201802466

专利信息

专利号:US-9929363-B2
优先权日:2013-08-05
标题:Composition and synthesis of aggregation-induced emission materials
发明人：TANG BENZHONG; Xie ni; LAM WING YIP
权利人:UNIV HONG KONG SCI & TECH
摘要:The present subject matter relates to compositions containing and synthesis of fluorescent materials e made from tetraphenylethylene (TPE) derivative compounds exhibiting aggregation induced emission (AIE) properties. Further contemplated herein are applications for TPE derivative compounds such as electroluminescent devices since they have a high efficiency, low turn on voltage, and excellent brightness. Additionally, application of TPE derivatives exhibiting AIE properties in various fields such as OLEDs, fingerprinting and forensic technology, and various other biological and industrial sectors are discussed.

专利号:US-2020190135-A1
优先权日:2016-11-16
标题 :Lasso structures and their synthesis
发明人：BODE JEFFREY; SAITO FUMITO
权利人:CHROMACON AG
摘要:A method for the synthesis of a molecular lasso structure in which a linear moiety is covalently attached to a cyclic moiety and with its free end is partially threaded through the orifice formed by the cyclic moiety, including the following steps: 1) provision of a cyclic and a first linear structural element and establishing conditions in which the first linear structural element is threaded through the orifice of the cyclic moiety; 2) covalently attaching a stopper element to one terminal end of the linear structural element; 3) separating unthreaded from threaded molecular assemblies by chemical or physical separation; and 4) reacting the threaded molecular assemblies with a second linear structural element so that it is covalently attached to the first linear structural element at its end opposite to the end where the stopper is attached, and so that the second linear structural element is covalently attached to the cyclic moiety.

专利号:US-11008273-B2
优先权日:2019-02-15
标题 :Process for the manufacture of fluorinated benzenes and fluorinated benzophenones, and derivatives thereof
发明人：ZHOU CHANGYUE; DU HONGJUN; WU WENTING
权利人:FUJIAN YONGJING TECH CO LTD
摘要:The invention relates to a new process for the manufacture or synthesis, respectively, of fluorinated benzenes and fluorinated benzophenones, and derivatives thereof, in particular of fluorobenzenes and derivatives thereof. The present invention particularly pertains to a novel environmentally friendly process for the synthesis of fluorinated benzenes and benzophenones as raw materials for the manufacture of polyaryletherketones (PAEKs).

专利号:US-8710261-B2
优先权日:2005-02-22
标 题:5-phenyl-pentanoic acid derivatives as matrix metalloproteinase inhibitors for the treatment of asthma and other diseases
发明人：PALLE VENKATA P; SATTIGERI VISWAJANANI JITENDRA; KHERA MANOJ KUMAR; VOLETI SREEDHARA RAO; RAY ABHIJIT; DASTIDAR SUNANDA G
权利人:PALLE VENKATA P; SATTIGERI VISWAJANANI JITENDRA; KHERA MANOJ KUMAR; VOLETI SREEDHARA RAO; RAY ABHIJIT; DASTIDAR SUNANDA G; RANBAXY LAB LTD
摘要:The present invention relates to Compounds having the structure of Formula I: wherein n is an integer from 1 to 5; R 1 is optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, heteroaryl, aralkyl, alkoxy, aryloxy, alkenyloxy or alkynyloxy; R 2 is alkenyl, allcynyl, aryl, heterocyclyl, heteroaryl, cycloalkyl, NR 4 R 5 , —NHC(â•?Y)R 4 , —NHC(â•?Y)NR 5 R χ , —NHC(â•?O)OR 4 , —NHSO 2 R 4 , C(â•?Y)NR 4 R 5 , C(â•?O)OR 6 [wherein Y is oxygen or sulphur], OR 5 , —O(Câ•?O)NR 4 R 5 , O-acyl, S(O) m R 4 , —SO 2 N(R 4 ) 2 , cyano, amidino or guanidino [wherein R 4 is alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, heteroaryl, aralkyl, heteroarylalkyl, heterocyclylalkyl or cycloalkylalkyl and m is an integer 0-2; R 5 is hydrogen or R 4 ; R x is R 4 or —SO 2 N(R 4 ) 2 and R 6 is hydrogen, alkyl, cycloalkyl, aralkyl, heteroarylalkyl, heterocyclylalkyl or cycloalkylalkyl]; R 3 is hydrogen, fluorine, alkyl, cycloalkylalkyl or aralkyl; A is OH, OR 4 , —OC(â•?O)NR 4 R 5 , O-acyl, NH 2 , NR 4 R 5 , —NHC(â•?Y)R 4 , —NHC(â•?Y)NR 5 R x , —NHC(â•?O)OR 4 , —NHSO 2 R 4 , and to processes for the synthesis of the same. This invention also relates to pharmacological compositions containing the compounds of the present invention, and methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterize by over-expression and over-activation of an matrix metalloproteinase, using the compounds.

专利号:US-2014371418-A1
优先权日:2012-01-05
标 题 :Biological synthesis of p-aminobenzoic acid, p-aminophenol, n-(4-hydroxyphenyl)ethanamide and derivatives thereof
发明人：NG WING ON; WATANABE SHINGO; HUMPHREYS ROBERT W R; SLATER STEVEN C
权利人:PAROMATICS LLC
摘要:The invention generally relates to biological engineering of microorganisms and production of chemical compounds therefrom. More particularly, the invention relates to novel genetically engineered microorganisms for the fermentative production of p-aminobenzoic acid and related compounds from fermentable carbon substrates. The biologically derived PABA and related compounds from fermentable carbon substrates can be used in a number of applications including as a food supplement or raw materials for the syntheses of other industrial chemicals or polymers.

专利号:US-8242273-B2
优先权日:2005-07-28
标 题:Synthesis of 4/5-pyrimidinylimidazoles via sequential functionalization of 2,4-dichloropyrimidine
发明人：DENG XIAOHU; MANI NEELAKANDHA
权利人:DENG XIAOHU; MANI NEELAKANDHA; JANSSEN PHARMACEUTICA NV
摘要:This invention relates to methods of making pyrimidinyl-substituted imidazole compounds by sequential substitution of the 4- and 2-chloro groups of 2,4-dichloropyrimidine, nucleophilic substitution to form pyrimidinylalkyne derivatives, oxidation to the corresponding 1,2-diketones, and cyclocondensation reactions.