CAS: 388-82-9; 2,2'-Difluoro-1,1'-Biphenyl

上下游产品

CAS号1072-85-1 1-溴-2-氟苯 | CAS号1993-03-9 2-氟苯硼酸 | CAS号348-51-6 2-氯氟苯 | CAS号104-92-7 对溴苯甲醚 | CAS号106-41-2 对溴苯酚 | CAS号95-56-7 2-溴苯酚 | CAS号445-29-4 邻氟苯甲酸 | CAS号578-57-4 邻溴苯甲醚 | CAS号462-06-6 氟苯 | CAS号88229-82-7 2-fluoro-1,3-bi... | CAS号88229-83-8 2,2',2'',2'''-t... | CAS号88229-94-1 1,3-bis[3-(brom...

📜氟苯置于2,2,6,6-四甲基哌啶,正丁基锂,Copper(Ll) Bromide,硝基苯体系中,用 四氢呋喃,正己烷 用作溶剂,化学反应 4.75H,以35%的收率获得2,2-二氟联苯
参考文献:氟化低聚亚苯基的梯级化无催化剂合成邻杂苯乙炔
标题:氟化低聚亚苯基的梯级化无催化剂合成邻杂苯乙炔
摘要:报道了一种新颖的无催化剂方法,用于从氟化低聚亚苯基制得苯并环氧基的含氧杂环.与现有方法不同,本发明的反应不需要含氧的前体,而是依赖于外部氧源叔丁醇钾,它可作为o 2−合成子.该反应的自由基性质即使在存在强供电子基团的情况下也能促进亲核取代,并能实现完全环化所需的叔丁基化.还证明了该方法适用于引入含氧的五元,六元和七元环,而多次环化也为阶梯型邻杂并苯和低聚二苯并呋喃开辟了一条短的合成途径.
Doi:10.1002/anie.202007427

专利信息

专利号:WO-9967219-A1
优先权日:1998-06-22
标 题:Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
发明人：AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
权利人:ELAN PHARM INC; LILLY CO ELI; AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
摘要:Compounds of formula (I), wherein W is a cyclic group of the type (2); (3); Y is represented by the formula (II); these compounds inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:WO-9966934-A1
优先权日:1998-06-22
标 题 :CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS
发明人：AUDIA JAMES E; DRESSMAN BRUCE A; SHI QING
权利人:ELAN PHARM INC; LILLY CO ELI; AUDIA JAMES E; DRESSMAN BRUCE A; SHI QING
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:WO-2016156282-A1
优先权日:2015-04-02
标 题 :Novel triazole compounds for controlling phytopathogenic harmful fungi
发明人：COQUERON PIERRE-YVES; Greul Jörg; HOLMWOOD GRAHAM; DAHMEN PETER; WACHENDORFF-NEUMANN ULRIKE; BENTING JÃœRGEN; BERNIER DAVID; MILLER RICARDA; GENIX PIERRE; WITTROCK SVEN; VORS JEAN-PIERRE; KENNEL PHILIPPE; Brunet Stéphane; NAUD SÉBASTIEN; MEISSNER RUTH; LISHCHYNSKYI ANTON
权利人:BAYER CROPSCIENCE AG
摘要:The present invention relates to a novel triazole compound and its salts and N-oxides, a composition comprising such compound, a method for curatively or preventively controlling phytopathogenic harmful fungi of plants or crops comprising the step of applying such compound or composition, to the use of such compound or such composition to control phytopathogenic harmful fungi and to a seed that has been treated with such a compound or such a composition. Further the present invention relates to novel epoxides which are useful intermediates in the synthesis of the triazole compounds of the invention.

专利号:EP-3844240-B1
优先权日:2018-05-30
标题:Method for synthesis of blue-emitting znse1-xtex alloy nanocrystals

专利号:US-2009137577-A1
优先权日:2007-06-29
标 题 :Heterocyclic compounds
发明人：DUPLANTIER ALLEN J; EFREMOV IVAN; ZHANG LEI; MAKLAD NOHA S; O'SULLIVAN THERESA
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I n n n n n n n n n n as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:CN-101768447-B
优先权日:2010-01-14
标 题:A kind of polyfluorinated terphenyl liquid crystal compound and its synthesis method and application