CAS: 33233-67-9; 4-(((Tert-Butoxycarbonyl)Amino)Methyl)Benzoic Acid

该化合物是一种受保护的氨基酸衍生物,其成分为三丁基碳基(Boc)组和苯并硫酸混合物.该化合物广泛用于合成和有机化学,作为一个多用途建筑块,在基本条件下提供稳定性,同时允许在酸条件下有选择地进行非保护.Boc组为杀伤人员地雷功能提供有效保护,防止合成过程中出现意外的侧面反应.carboxylic酸组通过配对反应进一步实现功能化.其晶体固体形式确保了处理和储存的方便性.这一中间体因其可靠的再活动性和与标准合成议定书的兼容性,在制药研究和生物活性分子的开发方面特别宝贵.

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CAS号56-91-7 氨甲苯酸 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号39895-56-2 4-胺甲基苯甲醇 | CAS号67688-72-6 4-(氨基甲基)-苯甲酸盐酸盐 | CAS号120157-96-2 4-(B°C-氨甲基)苯甲酸甲酯 | CAS号34619-03-9 碳酸二叔丁酯 | CAS号506-59-2 盐酸二甲胺 | CAS号541-41-3 氯甲酸乙酯 | CAS号123-91-1 1,4-二氧六环 | CAS号7732-18-5 水 | CAS号6232-11-7 4-氨甲基苯甲酸甲酯盐酸盐 | CAS号123986-64-1 4-(羟甲基)苄基氨基甲酸叔丁酯 | CAS号156866-52-3 4-甲酰苄基氨基甲酸叔丁酯 | CAS号120157-96-2 4-(B°C-氨甲基)苯甲酸甲酯 | CAS号66389-80-8 4-氰基苄基氨基甲酸叔丁酯 | CAS号905818-85-1 4-[(benzylamino...

合成工艺路线路线简述

    📜4-氨甲基苯甲酸置于sodium Hydroxide体系中,用 1,4-二氧六环,水 作为反应溶剂,化学反应生成 4-[(叔丁氧羰基氨基)甲基]苯甲酸
    参考文献:Pyrimidine Derivatives And Methods Of Making And Using These Derivatives
    标题:Pyrimidine Derivatives And Methods Of Making And Using These Derivatives
    摘要:本发明揭示了化合物及其药用可接受的盐,用于治疗患有疾病的患者.这些疾病包括癌症,以及免疫受损患者中由肺孢子虫和弓形虫引起的继发性感染.这些化合物本身,制备这些化合物的方法以及使用这些化合物的方法都被揭示.

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    专利信息


    专利号:US-11679168-B2
    优先权日:2018-09-14
    标 题 :Caspase-3-triggered molecular self-assembling PET probes and uses thereof
    发明人:RAO JIANGHONG; CHENG YUNFENG; CHEN MIN; XIE JIANGHANG; CHEN ZIXIN
    权利人:UNIV LELAND STANFORD JUNIOR; THE BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIV
    摘要:Embodiments of the synthesis, radiolabeling and biological applications of an activatable tracer that undergoes intramolecular cyclization and aggregation upon activation by cleavage of a blocking moiety are provided. The probes of the disclosure allow for target-controlled self-assembly of small molecules in living subjects for imaging and drug delivery. The aggregated nanoprobes of the disclosure may be detectable optically, by PET detection, magnetic resonance imaging, and the like depending on the detectable reporter attached to the nanoprobe.

    专利号:US-5916899-A
    优先权日:1996-10-18
    标 题:Isoquinoline derivatives and isoquinoline combinatorial libraries
    发明人:KIELY JOHN S; GRIFFITH MICHAEL C
    权利人:TREGA BIOSCIENCES INC
    摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinolines as well as novel libraries comprised of many such compounds, and methods of synthesizing the libraries.

    专利号:US-6417195-B1
    优先权日:1999-02-22
    标题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
    发明人:LEBL MICHAL
    权利人:LION BIOSCIENCE AG
    摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compounds.

    专利号:US-5874443-A
    优先权日:1995-10-19
    标 题:Isoquinoline derivatives and isoquinoline combinatorial libraries
    发明人:KIELY JOHN S; GRIFFITH MICHAEL C
    权利人:TREGA BIOSCIENCES INC
    摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinolines as well as novel libraries comprised of many such compounds, and methods of synthesizing the libraries.

    专利号:US-8450529-B2
    优先权日:2008-10-02
    标 题:Branched polyamines and formulations thereof for use in medical devices
    发明人:KAPIAMBA MBIYA
    权利人:KAPIAMBA MBIYA; COVIDIEN LP
    摘要:The present disclosure provides for the synthesis of branched polyamines. In embodiments, branched polyamines may be formed by reacting a branched polyol with a nitroaryl carboxylic acid to form a nitrobenzoyl ester which, in turn, may then be subjected to a hydrogenating step to form the branched polyamine. The resulting branched polyamine may then be reacted with another hydrogel precursor to form a hydrogel.

    专利号:WO-0102375-A1
    优先权日:1999-07-01
    标 题:Process for synthesizing oxadiazoles
    发明人:DENER JEFFREY MARK; LY CUONG QUOC
    权利人:AXYS PHARM INC; DENER JEFFREY MARK; LY CUONG QUOC
    摘要:The present invention relates to a process for the synthesis of a single as well as large array of oxadiazole based organic compounds. These oxadiazole based organic compounds are represented by compounds of formula (I).

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1557/s43579-025-00869-9
    摘要:Nishikawa Y, Kanao Y, Nakano K. Precise synthesis of poly(propylene carbonate)-block-poly(α-amino acid)s via copolymerization of propylene oxide with carbon dioxide and ring-opening polymerization of α-amino acid N-thiocarboxyanhydrides. MRS Commun. 2025 Nov 23;15(6):1229–35. doi: 10.1557/s43579-025-00869-9.
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