CAS: 27550-59-0; 5-Hydroxyisobenzofuran-1,3-Dione

上下游产品

4-羟基邻苯二甲酸 4-Hydroxyphthalic Acid 610-35-5
4-羟基邻苯二甲酸二乙酯 Diethyl 4-Hydroxyphthalate 64139-21-5
5-氨基-2-苯并呋喃-1,3-二酮 4-Aminobenzene-1,2-Dicarboxylic Acid Anhydride 17011-53-9

4-磺酰水杨酸置于sodium Hydroxide体系中,用 水 用作溶剂,化学反应 3.0H,反应生成4-羟基苯酐
参考文献:Dental Materials With Improved Hydrolysis Stability Based On Phthalic Acid Monomers
标题:Dental Materials With Improved Hydrolysis Stability Based On Phthalic Acid Monomers
摘要:含有一种聚合性邻苯二甲酸衍生物的牙科材料,其通式为i:其中r1═h,甲基或c1-C5烷基残基;R2═h,苯基,苄基或c1-C8烷基残基;Q1=不存在或是c1-C15烷基氧化物,碳链可以被o或s中断;Q2=不存在或是(N+1)-价脂肪族c1-C20残基,碳链可以被o或s中断,且q1和q2不能同时不存在;X=不存在,是o,S或(-co-nr4-)-,其中r4为h,Ch3或c2H5;Y=不存在,是o,S或(-co-nr5-)-,其中r5为h,Ch3或c2H5;N,M=分别独立地表示1,2或3;R3=h,Ch3,C2H5,Cl,Br或och3,其中苯环的两个羧基可以共同形成酐基.

专利信息

专利号:US-2011263540-A1
优先权日:2008-07-25
标题 :Small-molecule inhibitors of protein synthesis inactivating toxins
发明人：PANG YUAN-PING; TUMER NILGUN EREKEN; MILLARD CHARLES B
权利人:PANG YUAN-PING; TUMER NILGUN EREKEN; MILLARD CHARLES B
摘要:Small-molecule inhibitors of a protein synthesis inhibiting toxin, e.g., ricin, abrin, Shiga, and Shiga-like toxins, as well as methods of using the inhibitors are provided. Further provided are methods of identifying small-molecule inhibitors of a protein synthesis inhibiting toxin.

专利号:US-5760240-A
优先权日:1992-06-23
标题:Taxoid synthesis
发明人：NICOLAOU K C; CLAIBORNE CHRISTOPHER F; NANTERMET PHILIPPE G; COULADOUROS ELIAS A; SORENSON ERIK J
权利人:SCRIPPS RESEARCH INST
摘要:Bioactive ABC taxoids accessible by convergent synthesis have an intact AB ring framework of taxol, including the C13 side chain, and an aromatic C ring which substitutes for the CD ring system found on native taxol. The aromatic C ring may be substituted or unsubstituted. MPT derivatives of ABC taxoids are also disclosed.

专利号:US-2007060499-A1
优先权日:2005-09-15
标 题 :Chloroquine combination drugs and methods for their synthesis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention discloses compositions of chloroquine-coupled active agents, including methods for their preparation. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the active agent is delivered, thereby reducing the overall dosage needed. The compositions comprise a chloroquine substance coupled to an active agent directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing active agents for therapeutic or other medical uses. The invention also discloses carrier compositions that are coupled to targeting molecules for targeting the delivery of chloroquine substances and active agents to their site of action.

专利号:US-2007166281-A1
优先权日:2004-08-21
标题 :Chloroquine coupled antibodies and other proteins with methods for their synthesis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention discloses compositions of chloroquine-coupled active agents such as therapeutic antibodies or insulin, including methods for their preparation. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the drug is delivered, thereby reducing the overall dosage needed. The compositions comprise a chloroquine substance coupled to a drug directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing the drug for therapeutic or other medical uses. The invention also discloses carrier compositions that are coupled to targeting molecules for targeting the delivery of chloroquine substances and antibody or insulin to their site of action.

专利号:WO-2008103409-A2
优先权日:2007-02-22
标题 :Compositions of chloroquine coupled to antibodies and to other proteins with methods for their synthesis

专利号:WO-2010053606-A9
优先权日:2008-07-25
标 题:Small-molecule inhibitors of protein synthesis inactivating toxins