CAS: 23513-15-7; (S)-5-Hydroxy-1-(4-Hydroxy-3-Methoxyphenyl)Tetradecan-3-One

该化合物是一种生物活性化合物,主要在姜(Zingiber officinale)中发现,以其潜在的健康惠益和独特口味特征而著称,被归类为酚类化合物,其特点是长碳链,具有独特性.10Gingerol的分子结构包括一个增强抗氧化活动的氢氧化物组.该化合物因其防炎,止痛和抗癌特性而得到承认,使其成为营养和医学研究的话题.此外,10Gingerol表现出了一种稀有的品味,是姜的标志,而且常常对香料的特征负责.其有机溶液中的溶性以及水溶性有限是显著的物理特性.该化合物还因其对肠胃健康和代谢过程的潜在影响而进行了研究.

结构式图片

物理性质

MSDS等安全信息

欧盟法规

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上下游产品

hexahydro-2H-oxepin-2-one (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid methyl 6-hydroxycaproate 3-(4-hydroxy-3-methoxyphenyl)propionic acid (3R,5S)-[10]-gingerdiol

合成工艺路线路线简述

    📜3-(4-羟基-3-甲氧基苯基)丙酸置于吡啶,Chromium(Vi) Oxide,Lithium Aluminium Tetrahydride,硫酸,三氟化硼乙醚,四丁基氟化铵,四丁基碘化铵,Sodium Hydride,对甲苯磺酸,Calcium Carbonate,碘甲烷体系中,用 四氢呋喃,乙醚,乙醇,二氯甲烷,氯仿,水,乙腈 用作溶剂,化学反应 37.0H,反应生成10-姜酮醇
    参考文献:Total Synthesis Of Natural Gingerols,The Three Active Principles Of Ginger
    标题:Total Synthesis Of Natural Gingerols,The Three Active Principles Of Ginger
    摘要:Natural Gingerols,(+)(S)[6]-,(+)(S)[8]-,And (+)(S)[10]-Gingerols,The Three Active Principles Of Ginger,Have Been Prepared From A Common Optically Active Intermediate 9 Which Was Readily Made By Asymmetric Synthesis From A Chiral Beta-Keto Sulfoxide 5.
    Doi:10.1021/jo00060A038

    海关参考信息

    专利信息


    专利号:CN-103159600-A
    优先权日:2013-03-27
    标 题:Chemical Synthesis Process of Gingerol

    专利号:CN-115299543-B
    优先权日:2022-08-12
    标 题:A kind of solid beverage that promotes the synthesis and metabolism of human dopamine and its preparation method

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    主要参考文献


    1: Zhang F, Thakur K, Hu F, Zhang JG, Wei ZJ. Cross-talk between 10-gingerol and its anti-cancerous potential: a recent update. Food Funct. 2017 Aug 1;8(8):2635-2649. doi: 10.1039/c7fo00844a. Epub 2017 Jul 26. 32(10):1885-1907. doi: 10.1002/ptr.6134. Epub 2018 Jul 16.
    80:106196. doi: 10.1016/j.intimp.2020.106196. Epub 2020 Jan 21. 22(5):157. doi: 10.1208/s12249-021-02006-w. 9(7):3917-3931. doi: 10.1002/fsn3.2381.
    6: Zang L, Kagotani K, Nakayama H, Bhagat J, Fujimoto Y, Hayashi A, Sono R, Katsuzaki H, Nishimura N, Shimada Y. 10-Gingerol Suppresses Osteoclastogenesis in RAW264.7 Cells and Zebrafish Osteoporotic Scales. Front Cell Dev Biol. 2021 Mar 3;9:588093. doi: 10.3389/fcell.2021.588093.

    合成参考文献


    摘要:Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal., 25(231), 1990
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