CAS: 1821-52-9; 2-Hydroxy-3-(1H-Indol-3-yl)Propanoic Acid

上下游产品

Indole-3-pyruvic acid 3-(indol-3-yl)pyruvic acid methyl ester indol-3-yl-pyruvic acid ethyl ester hydroxy-indol-3-ylmethyl-malonic acid(S)-2-hydroxy-3-(1H-indol-3-yl)-propionic acid 3-indol-3-yl-propane-1,2-diol methyl 2-tosyloxy-3-(3-indolyl)propionate Toluene-4-sulfonate1-[2-(1H-indol-3-yl)-2-methoxycarbonyl-ethyl]-4-methyl-pyridinium;

📜3-(3-吲哚基)-2-氧代丙酸置于乙醇,钯体系中,化学反应生成3-吲哚-乳酸
参考文献:Preparation And Properties Of β-3-Indolyl Compounds Related To Tryptophan Metabolism1
标题:Preparation And Properties Of β-3-Indolyl Compounds Related To Tryptophan Metabolism1
摘要:
Doi:10.1021/jo01102A025

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-11718864-B2
优先权日:2015-09-23
标 题 :Cells and method of cell culture
发明人：HILLER GREGORY WALTER; MITCHELL JEFFREY JOSEPH; MULUKUTLA BHANU CHANDRA; PEGMAN PAMELA MARY
权利人:PFIZER
摘要:The invention relates to a method of cell culture where the cells are modified to reduce the level of synthesis of growth and/or productivity inhibitors by the cell. The invention also relates to a method of cell culture for improving cell growth and productivity, in particular in fed-batch culture of mammalian cells at high cell density. The invention further relates to a method of producing cells with improved cell growth and/or productivity in cell culture and to cells obtained or obtainable by such methods.

专利号:US-9102961-B2
优先权日:2009-03-11
标 题 :Biological synthesis of difunctional hexanes and pentanes from carbohydrate feedstocks
发明人：BAYNES BRIAN M; GEREMIA JOHN MICHAEL; LIPPOW SHAUN M
权利人:CELEXION LLC
摘要:Provided herein are methods for the production of difunctional alkanes in microorganisms. Also provided are enzymes and nucleic acids encoding such enzymes, associated with the difunctional alkane production from carbohydrates feedstocks in microorganisms. The invention also provides recombinant microorganisms and metabolic pathways for the production of difunctional alkanes.

专利号:US-12157908-B2
优先权日:2019-02-25
标 题:Cell-free protein synthesis platforms derived from clostridia extracts
发明人：JEWETT MICHAEL CHRISTOPHER; KRUGER-GERICKE ANTJE; MUELLER ALEXANDER PAUL; KOEPKE MICHAEL
权利人:UNIV NORTHWESTERN; LANZATECH INC
摘要:Disclosed are compositions, methods, and kits for performing cell-free RNA transcription and/or cell-free protein synthesis (CFPS). The disclosed compositions, methods, and kits include or utilize components prepared from a species of Clostridia such as cellular extracts from Clostridium autoethanogenum.

专利号:US-2013017593-A1
优先权日:2009-03-11
标题:Biological Synthesis of Difunctional Hexanes and Pentanes from Carbohydrate Feedstocks

专利号:EP-1501503-B1
优先权日:2002-05-09
标 题:Substantially pure solid form of the enol tautomer of 3-indolypyruvic acid for use in the treatment of central nervous system disturbances
发明人：POLITI VINCENZO; SELLA ANTONIO; BARTOLINI BARBARA; MARGONELLI ANDREA; SOMMA FRANCESCA; CORNIELLO CRISTINA
权利人:POLIFARMA SPA
摘要:The enol tautomer of 3-indolylpyruvic acid in stable and pure form, as well as alkali and alkali-earth salts thereof are produced by synthesis process. The enol tautomer comprises only the geometric isomer (Z) and it is the only one tautomeric form having relevant pharmacological effects. The compounds obtained exhibited relevant biochemical and pharmacological properties in pathological situations like anxiety, depression, behaviour disturbances, neuronal degenerations, etc.