CAS: 158435-41-7; 2-Chloro-4-Bromobenzaldehyde

相似化合物

154607-01-9 59748-90-2 185312-82-7

上下游产品

4-bromo-2-chloro-1-(dibromomethyl)benzene (4-bromo-2-chlorophenyl)methanol 4-bromo-2-chlorobenzonitrile 4-bromo-2-chloroiodobenzene (R)-N-(4-bromo-2-chlorobenzylidene)-2-methylpropane-2-sulfinamide 4-bromo-2-chloro-1-((E)-2-nitro-propenyl)-benzene 1-(4-bromo-2-chlorobenzyl)piperidine

4-溴-2-氯甲苯置于tetrabutylammonium Tetrafluoroborate,水体系中,用38%的收率获得2-氯-4-溴苯甲醛
参考文献:苄基 C−x 键与羰基的无金属和无添加剂电化学氧化
标题:苄基 C−x 键与羰基的无金属和无添加剂电化学氧化
摘要:实现了一种可扩展的电化学策略,用于将各种苄基 Cx 键氧化为羰基.该方案在温和的反应条件和空气气氛下在简单的整体电解池中运行,H 2 O 作为氧源,廉价的石墨板作为阳极和阴极.
Doi:10.1002/ejoc.202300570

专利信息

专利号:US-11780834-B2
优先权日:2018-06-21
标题:Solid forms of 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3- yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol and processes for preparing fused tricyclic compounds comprising a substituted phenyl or pyridinyl moiety, including methods of their use
发明人：CHUNG CHEOL KEUN; XU JIE; IDING HANS; CLAGG KYLE; DALZIEL MICHAEL; FETTES ALEC; GOSSELIN FRANCIS; LIM NGIAP-KIE; MCCLORY ANDREW; ZHANG HAIMING; CHAKRAVARTY PAROMA; NAGAPUDI KARTHIK; ROBINSON SARAH
权利人:HOFFMANN LA ROCHE; GENENTECH INC
摘要:Provided herein are solid forms, salts, and formulations of 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol, processes and synthesis thereof, and methods of their use in the treatment of cancer.