CAS: 92260-81-6; 8,9-Dihydro-2,9A-Diazabenzo[cd]Azulene-1,6(2H,7H)-Dione

该化合物是一个环状有机化合物,其特点是其复杂的结合环结构,将氮原子结合到其框架之内.该化合物具有双环系统,包括单体和芳香特性,有助于其独特的化学特性.二元功能组的存在表明,它含有两个碳基(C=O)组,可影响其再活动性和有机合成或材料科学的潜在应用.结构中的氮原子还能够产生基本性影响并影响化合物与其他化学物种的互动.通常,这种性质的化合物可能具有有趣的电子特性,使其可以用于光化学或潜在染料的研究.但是,需要从实验数据或文献中参考具体的物理特性,如溶性,熔点和光谱特性,以便在不同环境中进行详细的应用和行为.

英文名称8,9-Dihydro-2,9A-Diazabenzo[cd]Azulene-1,6(2H,7H)-Dione
中文名称8,9-二氢2,9a二氮杂苯并[cd]薁-1,6-(2H,7H)-二酮
IUPAC名称8,9-dihydro-2,9a-diazabenzo[cd]azulene-1,6(2H,7H)-dione
其它别名5,6-二氢-咪唑并[4,5,1-Jk][1]苯并氮杂卓-2,7(1H,4H)-二酮; 5,6-Dihydroimidazo[4,5,1-Jk][1]Benzazepine-2,7(1H,4H)-Dione
CAS编号92260-81-6
MFCD编号:MFCD18252621
EINECS号:695-944-9
分子式:C11H10N2O2
分子量:202.21
产品CID: 1960234
产品分类有机原料→分子砌块→芳杂环类化合物→苯并咪唑类化合物

相似结构搜索
InChIKey: QDMYVAGJPVQRSQ-UHFFFAOYSA-N
InChI=1S/C11H10N2O2/c14-9-5-2-6-13-10-7(9)3-1-4-8(10)12-11(13)15/h1,3-4H,2,5-6H2,(H,12,15)…
计算化学: 氢键受体数3.0氢键供体数1.0可旋转键数0.0

相似化合物

1021910-71-3 1797124-71-0 75655-10-6

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别急性毒性类别4(经口)
警示词Warning(警告)
危险描述H302 |吞咽有害.
防范说明P264-P270-P280-P302+P352-P330-P362+P364-P501

欧盟法规

REACH注册

上下游产品

CAS号3273-68-5 2,3-二氢-2-氧-1H-苯... | CAS号1021910-67-7 chloro 2,3-dihy...

合成工艺路线路线简述

合成目标产物 5,6-Dihydroimidazo[4,5,1-Jk][1]Benzazepine-2,7(1H,4H)-Dione 主要起始原料 1-Isopropenyl-2-Benzimidazolidinone
3273-68-5 = 92260-81-6
反应条件:1.1 Reagents: Thionyl Chloride1.2 Reagents: Aluminum Chloride Solvents: 1,2-Dichloroethane
标题:Synthesis Of Imidazobenzazepinethiones: A New Series Of Hiv-1 Reverse Transcriptase Inhibitors
作者:Salaski,Edward J.
参考文献:Tetrahedron Letters 日期:1995 卷标:36(9) 页码:1387-90]

1021910-67-7 = 92260-81-6
反应条件:1.1 Reagents: Aluminum Chloride Solvents: Dichloromethane; 2 - 5 H,2.7 Bar,10 - 20 °C1.2 Reagents: Hydrochloric Acid Solvents: Water; 5 - 20 °C; 30 - 90 Min,10 - 30 °C
标题:Process For Making A Crystalline Zilpaterol Salt
参考文献:World Intellectual Property Organization]

3273-68-5 = 92260-81-6
反应条件:1.1 Reagents: Thionyl Chloride Solvents: Dichloromethane; 2 H,Rt1.2 Reagents: Aluminum Chloride Solvents: Dichloromethane; Rt; Overnight,Rt; 2 H,Reflux1.3 Reagents: Hydrochloric Acid Solvents: Water; Cooled
标题:Preparation Of Imidazobenzazepinones As β2 Adrenoceptor Agonists For Use As Livestock Feed Additives And As Drugs.
参考文献:United States]

1021910-67-7 = 92260-81-6
反应条件:1.1 Reagents: Aluminum Chloride Solvents: Dichloromethane; Rt; Overnight,Rt; 2 H,Reflux1.2 Reagents: Hydrochloric Acid Solvents: Water; Cooled
标题:Preparation Of Imidazobenzazepin-2(1H)-Ones As β2 Adrenoceptor Agonists.
参考文献:United States]

1021910-67-7 = 92260-81-6
反应条件:1.1 Reagents: Aluminum Chloride Solvents: Dichloromethane; 2 - 5 H,2.7 Bar,60 °C; 1 H,60 °C; 60 °C -> 12 °C1.2 Reagents: Hydrochloric Acid Solvents: Water; Rt -> 0 °C; 0 °C -> 15 °C
标题:Processes For Preparation Of Zilpaterol Via Chlorination Of 4-(2-Oxo-2,3-Dihydrobenzimidazol-1-Yl)Butyric Acid Or Nitrosation Of 8,9-Dihydro-2H,7H-2,9A-Diazabenzo[cd]Azulene-1,6-Dione.
参考文献:World Intellectual Property Organization]

3273-68-5 = 92260-81-6
反应条件:1.1 Reagents: Thionyl Chloride Solvents: Dichloromethane; 2 H,Rt1.2 Reagents: Ammonium Chloride Solvents: Dichloromethane; Rt; Overnight,Rt; 2 H,Reflux1.3 Reagents: Hydrochloric Acid Solvents: Water; Cooled
标题:Preparation Of Imidazo[4,5,1-Jk][1]Benzazepin-2(1H)-One Derivatives As Anabolic Agents
参考文献:World Intellectual Property Organization]

92260-80-5 = 92260-81-6 [标题:Reaction Conditions
标题:Derivatives Of 6-Amino-7-Hydroxy-4,5,6,7-Tetrahydroimidazo[4,5,1-Jk][1]Benzazepin-2(1H)-One.
参考文献:France]

= 92260-81-6 [标题:Reaction Conditions
标题:4,5-Dihydroimidazo[4,5,1-Jk][1]Benzazepine-2,7(1H,6H)-Dione And Its Preparation As An Antihypertensive And Vasodilator Intermediate
参考文献:Canada

5,6-Dihydro-1-Benzyl-Imidazo[4,5,L-J-K][1] Benzazepin-2,7[1H,4H]-Dione 反应生成咪唑并[4,5,1-Jk][1]苯并氮杂环庚烯-2,7(1H,4H)-二酮,5,6-二氢
参考文献:Frechet,D.;Nedelec,L.;Plassard,G.;Brown,N. L.
标题:Frechet,D.;Nedelec,L.;Plassard,G.;Brown,N. L.

海关参考信息

2902600000-乙苯
2912110000-甲醛
2912120000-乙醛
2912210000-苯甲醛
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-8629134-B2
优先权日:2007-02-01
标题:Enantioselective synthesis of 6-amino-7-hydroxy-4,5,6,7-tetrahydro-imidazo[4,5,1-jk][1]-benzazepin-2[1H]-one and zilpaterol
发明人：ALMENA-PEREA JUAN JOSE; BRINK MONIKA; GEIBETA GERHARD; KADYROV RENAT; MEYER THORSTEN
权利人:ALMENA-PEREA JUAN JOSE; BRINK MONIKA; GEIBETA GERHARD; KADYROV RENAT; MEYER THORSTEN; INTERVET INT BV
摘要:This invention relates to a process for the hydrogenation of a ketooxime to selectively form an aminoalcohol stereoisomer, and, in particular, to a process for the hydrogenation of 4,5-dihydro-imidazo[4,5,1-jk][1]benzazepin-2,6,7[1H]-trione-6-oxime or a salt thereof to selectively form a stereoisomer of 6-amino-7-hydroxy-4,5,6,7-tetrahydro-imidazo[4,5,1-jk][1]-benzazepin-2[1H]-one or a salt thereof. This invention also relates to the use of the 6-amino-7-hydroxy-4,5,6,7-tetrahydro-imidazo[4,5,1-jk][1]-benzazepin-2[1H]-one hydrogenation product or a salt thereof to selectively make a stereoisomer of zilpaterol or a salt thereof, as well as the use of such a zilpaterol stereoisomer or salt in methods of treatment and medicaments for animals.

专利号:EP-2109614-A1
优先权日:2007-02-01
标题:Enantioselective synthesis of 6-amino-7-hydroxy-4, 5, 6, 7-tetrahydro-imidazo [4, 5, 1-jk][1]-benzazepin-2 [1h]-one and zilpaterol

专利号:JP-2010517968-A
优先权日:2007-02-01
标题:Enantioselective synthesis of 6-amino-7-hydroxy-4,5,6,7-tetrahydro-imidazo [4,5,1-JK] [1] -benzazepin-2 [1H] -one and zilpaterol

专利号:RU-2433131-C2
优先权日:2007-02-01
标题:ENANTIOSELECTIVE SYNTHESIS OF 6-AMINO-7-HYDROXY-4,5,6,7-TETRAHYDROIMIDAZO[4,5,1-jk][1]BENZAZEPIN-2[1H]-ONE AND ZILPATEROL

专利号:EP-2109614-B1
优先权日:2007-02-01
标题:Enantioselective synthesis of 6-amino-7-hydroxy-4, 5, 6, 7-tetrahydro-imidazo [4, 5, 1-jk][1]-benzazepin-2 [1h]-one and zilpaterol

专利号:WO-2008092924-A1
优先权日:2007-02-01
标题:Enantioselective synthesis of 6-amino-7-hydroxy-4, 5, 6, 7-tetrahydro-imidazo [4, 5, 1-jk] [1] -benzazepin-2 [1h] -one and zilpaterol