CAS: 521-34-6; 5,7-Dihydroxy-8-(5-(5-Hydroxy-7-Methoxy-4-Oxo-4H-Chromen-2-yl)-2-Methoxyphenyl)-2-(4-Methoxyphenyl)-4H-Chromen-4-One

该化合物是一种主要与脊椎动物(日本伞状松)和其他锥虫物种隔离的双氟甲状腺素化合物,它显示出显著的生物活动,包括抗氧化剂,抗炎和潜在的抗癌特性.研究表明它有能力调节细胞路径,例如抑制NF-XXB信号,这可能有助于其治疗效果.Sciadopitysin 也研究其...

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CAS号3754-52-7 3'-iodo-5,7,4'-... | CAS号135159-01-2 (5,7-diisopropo... | CAS号7507-89-3 1-(2,6-二羟基-4-甲氧... | CAS号438051-00-4 3-[5,7-dihydrox... | CAS号100-06-1 对甲氧基苯乙酮

合成工艺路线路线简述

    📜3'-Jod-4',5,7-Trimethoxy-Flavon置于四(三苯基膦)钯 三氯化硼,Potassium Carbonate体系中,用 1,4-二氧六环,二氯甲烷,水 作为反应溶剂,化学反应 5.0H,反应生成 金松双黄酮
    参考文献:A New Strategy For The Synthesis Of Biflavonoids Via Arylboronic Acids.
    标题:A New Strategy For The Synthesis Of Biflavonoids Via Arylboronic Acids.
    摘要:Amentoflavone Derivatives Were Prepared By Catalytic Coupling Of 8-Flavoneboronic Acids With Iodoflavones. 3-Arylflavones,As Biflavonoid Synthon,Are Accessible By The Method.
    DOI:10.1016/s0040-4039(00)79688-2

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    专利信息


    专利号:CN-115612114-A
    优先权日:2021-07-14
    标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis

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    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: De L, Xing N, Du Q, Guo S, Wang S. Investigating the anti-lung cancer properties of Zhuang medicine Cycas revoluta Thunb. leaves targeting ion channels and transporters through a comprehensive strategy. Comput Biol Chem. 2024 Oct;112:108156. doi: 10.1016/j.compbiolchem.2024.108156. Epub 2024 Jul 19. 15(12):3675-3683. doi: 10.7150/jca.94202.
    3: Li YJ, Guo Q, Ye MS, Cai G, Xiao WF, Deng S, Xiao Y. YBX1 promotes type H vessel-dependent bone formation in an m5C-dependent manner. JCI Insight. 2024 Jan 11;9(4):e172345. doi: 10.1172/jci.insight.172345.
    4: Ijaz MU, Qamer M, Hamza A, Ahmed H, Afsar T, Abulmeaty M, Ayub A, Razak S. Sciadopitysin mitigates spermatological and testicular damage instigated by paraquat administration in male albino rats. Sci Rep. 2023 Nov 13;13(1):19753. doi: 10.1038/s41598-023-46898-z.

    合成参考文献


    参考文献:10.1021/np960057s
    摘要:Lale A, Herbert JM, Augereau JM, Billon M, Leconte M, Gleye J. Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes. J Nat Prod. 1996 Mar;59(3):273–6. doi: 10.1021/np960057s.
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