CAS: 499-75-2; 5-Isopropyl-2-Methylphenol

相似化合物

35946-91-9 89-83-8 89-83-8

上下游产品

methanol (S)-p-mentha-6,8-dien-2-one 2-oxo-1,4-cineol benzoic acid anhydridecarvacrol β-hydroxyethylether -piperidin1-(4-Hydroxy-6-isopropyl-3-methyl-phenyl)-methyl-piperidin 2-bromo-propionic acid-(5-isopropyl-2-methyl-phenyl ester) nicotinic acid-(5-isopropyl-2-methyl-phenyl ester)

香芹酚乙酸酯置于silica Gel,对甲苯磺酸体系中,用 水,甲苯 作为反应溶剂,化学反应 18.0H,以94%的收率获得产物香芹酚
参考文献:A Selective Hydrolysis Of Aryl Acetates
标题:A Selective Hydrolysis Of Aryl Acetates
摘要:芳基和萘基乙酸酯通过与饱和水的甲苯及吸附在硅胶上的对甲苯磺酸反应有效水解.该方法允许在存在其他酯基的情况下选择性水解芳基乙酸酯.
DOI:10.1055/s-1989-27277

专利信息

专利号:US-11667658-B2
优先权日:2021-06-30
标 题:Chemical synthesis of the organoarsenical antibiotic arsinothricin
发明人：ROSEN BARRY P; YOSHINAGA MASAFUMI; WNUK STANISLAW F; HOWLADER MD ABU HASAN; SUZOL SK MD SAZZAD HOSSAIN
权利人:ROSEN BARRY P; YOSHINAGA MASAFUMI; WNUK STANISLAW F; HOWLADER MD ABU HASAN; SUZOL SK MD SAZZAD HOSSAIN; THE FLORIDA INTERNATIONAL UNIV BOARD OF TRUSTEES
摘要:The subject invention provides methods for the chemical synthesis of racemic arsinothricin (D,L-AST), the novel organoarsenical antibiotic. One is by condensation of the 2-chloroethyl(methyl)arsinic acid with acetamidomalonate, and the second involves reduction of the N-acetyl-protected derivative of hydroxyarsinothricin (AST-OH) and subsequent methylation of the resulting sodium salt of trivalent arsenic intermediate with methyl iodide. The enzyme AST N-acetyltransferase (ArsN1) was utilized to purify L-AST from racemic AST. This expedient chemical synthesis of AST provides a source of this novel antibiotic for future drug development.

专利号:WO-2024130393-A1
优先权日:2022-12-21
标 题 :Nanoparticle and method of synthesis thereof
发明人：MOSKOVCHENKO SVITLANA
权利人:MOSKOVCHENKO SVITLANA
摘要:The present technology relates to nanoparticles, compositions comprising said nanoparticles, and methods of synthesis of said nanoparticles; wherein the nanoparticles comprise a metal nanoparticle core, a first coating of amphiphilic molecules, and a second coating of essential oil, essential oil primary constituent, or both, which combine the antimicrobial properties of metal nanoparticles, amphiphilic molecules, and essential oil or essential oil primary constituents.

专利号:US-12037302-B1
优先权日:2021-04-01
标 题:Compound for treatment of bacterial infections of different etiology in humans
发明人：NINKOV DUSAN
权利人:TESLA BIOSCIENCE AD BANJA LUKA
摘要:The invention relates to a novel compound manufactured with the procedure of synthesis of bouncing Carvacrol and Lidocaine into one stable compound. Use of the compound as an active compound/potent antimicrobial for the treatment of bacterial infections in humans caused by pathogens resistant to antibiotics, such as Methicillin-resistant Staphylococcus aureus (MRSA), Streptococcus faecalis, Mycobacterium tuberculosis, Escherichia spp. E. coli, Salmonella spp. Pasteurella spp., Corynebacterium spp., Bacillus spp., Bacillus anthracis, Clostridium spp., Spherophorus spp., Candida spp., Trichophyton spp., Microsporum spp., Mycobacterium spp., Vibrio spp., Cryptosporidium spp., Microsporidia spp., Listeria monocytogenes, Lawsonia intracellularis, Treponema dysenteriae, Enterococcus spp., Haemophilus spp., Campylobacter spp., Chlamydia spp., Brucella spp., and other pathogenic bacterial species.

专利号:US-2024374551-A1
优先权日:2023-05-12
标题:Entero-antiseptic for the treatment of gastrointestinal infections in humans
发明人：NINKOV DUSAN
权利人:NINKOV DUSAN
摘要:The invention relates to a novel compound manufactured with the procedure of synthesis of bouncing Thymol and Carvacrol into one solid and stable compound. Use of the compound as an active compound/potent entero-antiseptic for treating acute infectious gastroenteritis in humans, caused by E. coli, Salmonella, Campylobacter, Shigella, Vibrio, Yersinia, Listeria, and other bacteria. Additionally, its second formulation, with the coated cellulose, is used as an active compound/potent entero-antiseptic for treating chronic intestinal infections: Crohn's disease (inflammatory bowel disease—IBD).

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:EP-3991725-A1
优先权日:2020-11-02
标 题:Novel entero-antiseptic for the treatment of gastrointenstinal infections in humans
发明人：NINKOV DUSAN
权利人:NINKOV DUSAN
摘要:The invention relates to a novel compound manufactured with the procedure of synthesis of bouncing Thymol and Carvacrol into one solid and stabile compound. Use of the compound as an active compound/potent entero-antiseptic for the treatment of infectious acute gastroenteritis in humans, caused by E. coli, Salmonella, Campylobacter, Shigella, Vibrio, Yersinia, Listeria, and other bacteria. Additionally, its second formulation, with the coated cellulose, is used as an active compound/potent entero-antiseptic for the treatment of chronic intestinal infections: Crohn's disease (inflammatory bowel disease - IBD).