CAS: 487-06-9; 5,7-Dimethoxy-2H-Chromen-2-One

上下游产品

CAS号500-99-2 3,5-二甲氧基苯酚 | CAS号471-25-0 丙炔酸 | CAS号2732-18-5 5,7-二羟基香豆素 | CAS号74-88-4 碘甲烷 | CAS号708-76-9 4,6-二甲氧基水杨醛 | CAS号105-58-8 碳酸二乙酯 | CAS号15568-85-1 5-(甲氧亚甲基)-2,2-二... | CAS号623-47-2 丙炔酸乙酯 | CAS号121449-70-5 2-bromo-3,5-dim... | CAS号82235-61-8 2H-1-Benzopyran... | CAS号486-28-2 白蜡树精 | CAS号108-73-6 间苯三酚 | CAS号64-19-7 冰醋酸 | CAS号88140-30-1 5,7-dimethoxy-2... | CAS号61899-44-3 8-hydroxy-5,7-d...

📜2-Formyl-3,5-Dimethoxyphenyl 2-Chloroacetate 以 N,N-二甲基甲酰胺 作为反应溶剂,以35%的收率获得产物5,7-二甲氧基香豆素
参考文献:在银阴极还原取代的 2-氯乙酸苯酯:香豆素的电合成
标题:在银阴极还原取代的 2-氯乙酸苯酯:香豆素的电合成
摘要:To Explore The Electrosynthesis Of Coumarins,Cyclic Voltammetry And Controlled-Potential (Bulk) Electrolysis Have Been Employed To Investigate The Reduction Of The Carbon-Chlorine Bond Of Five Substituted Phenyl 2-Chloroacetates At Silver Cathodes In Dimethylformamide (Dmf) Containing 0.10 M Tetra-N-Butylammonium Tetrafluoroborate (Tbabf(4)) As Supporting Electrolyte; The Five Substrates Are 2-Formylphenyl 2-Chloroacetate (1A),2-Acetylphenyl 2-Chloroacetate (2A),Methyl 2-(2-Chloroacetoxy)Benzoate (3A),2-Formyl-5-Methoxyphenyl 2-Chloroacetate (4A),And 2-Formyl-3,5-Dimethoxyphenyl 2-Chloroacetate (5A). We Have Examined (A) The Effects Of Substituents On The Benzene Ring Of The Substrate As Well As The Nature Of The Aryl Carbonyl Moiety On The Formation Of The Coumarin Product And (B) The Effect Of Solvent-Namely,Dmf,Acetonitrile (Ch3Cn),Benzonitrile (Phcn),And Propylene Carbonate (Pc)-And Substrate Concentration On The Yield Of The Coumarin. It Was Found That The Most Unsubstituted Substrate (1A) Afforded The Highest Yield (41%) Of The Desired Coumarin In A Dmf-Tbabf(4) Medium. A Mechanistic Scheme Is Proposed To Account For The Formation Of The Coumarin. Furthermore,The Only Other Products Seen In These Reductions Are 2-Substituted Phenols,Which Are Precursors For Synthesis Of The Various Substrates. (C) 2014 The Electrochemical Society. All Rights Reserved.
DOI:10.1149/2.0551412Jes

专利信息

专利号:US-5139940-A
优先权日:1989-10-26
标题 :Activation compounds and methods of synthesis of activation compounds
发明人：ISAACS STEPHEN T; CIMINO GEORGE D; METCHETTE KENNETH C; TESSMAN JOHN W
权利人:ISAACS STEPHEN T; CIMINO GOERGE D; METCHETTE KENNETH C; TESSMAN JOHN W
摘要:The invention is directed to isopsoralen compound compositions that contain a variety of substitutions which yet permit their binding to nucleic acid polymers. Reaction conditions that activate these bound isopsoralens results in covalent crosslinking to the nucleic acid polymers. The resultant complex is inhibited from being a template for the template-directed enzymatic synthesis of a complementary nucleic acid polymer. Beside the isopsoralens compositions, the invention includes their synthesis, the nucleic acid complex production and detection, and the above inhibitory method of use of the isopsoralens.

专利号:EP-0497921-B1
优先权日:1989-10-26
标 题:Method for inhibiting enzymatic synthesis of nucleic acids using isopsoralens
发明人：ISAACS STEPHEN T; CIMINO GEORGE D; METCHETTE KENNETH C; TESSMAN JOHN W; HEARST JOHN E
权利人:ISAACS STEPHEN T; CIMINO GEORGE D; METCHETTE KENNETH C; TESSMAN JOHN W; HEARST JOHN E
摘要:The invention relates to a device, comprising means for providing electromagnetic radiation (101-106; 201-206; 301-308); means for supporting a sample (109;315) in a fixed relationship with said radiation providing means during irradiation; a housing (100;200;300) for containing said radiation providing means; and means for maintaining the temperature of said sample within a desired temperature range during said irradiation comprising a chamber (107;207;309) positioned interior to said housing and in a fixed relationship to said radiation providing means.

专利号:US-2010324266-A1
优先权日:2000-09-11
标题:Photocleavable Protecting Groups
发明人：BARONE ANTHONY D; MCGALL GLENN H
权利人:AFFYMETRIX INC
摘要:Novel compounds are provided, which are useful as linking groups in chemical synthesis, preferably in the solid phase synthesis of oligonucleotides and polypeptides. These compounds are generally photolabile and comprise protecting groups which can be removed by photolysis to unmask a reactive group. The protecting group has the general formula Y, wherein Y is a chemical structure as shown in FIG. 1 . Also provided is a method of forming, from component molecules, a plurality of compounds on a support, each compound occupying a separate predefined region of the support, using the protected compounds described above.

专利号:US-2011028350-A1
优先权日:1995-12-15
标题:Photocleavable protecting groups
发明人：MCGALL GLENN H; BARONE ANTHONY D
权利人:AFFYMETRIX INC
摘要:Novel compounds are provided, which are useful as linking groups in chemical synthesis, preferably in the solid phase synthesis of oligonucleotides and polypeptides. These compounds are generally photolabile and comprise protecting groups which can be removed by photolysis to unmask a reactive group. The protecting group has the general formula Y, wherein Y is a chemical structure as shown in FIG. 5. Also provided is a method of forming, from component molecules, a plurality of compounds on a support, each compound occupying a separate predefined region of the support, using the protected compounds described above.

专利号:CN-107531737-A
优先权日:2015-03-25
标 题:Synthesis of deoxyglycosamine