CAS: 4629-80-5; 1,3-Dimethylpiperidin-4-One

相似化合物

2091951-57-2 2199214-87-2 1527494-98-9

上下游产品

CAS号109682-06-6 methyl(β-methox... | CAS号21388-25-0 3-Methylamino-2... | CAS号544-97-8 二甲基锌 | CAS号132532-18-4 4-(3-chloro-1,2... | CAS号91016-40-9 1-Penten-3-one,... | CAS号74-89-5 氨基甲烷 | CAS号2999-74-8 二甲基镁 | CAS号75-16-1 甲基溴化镁 | CAS号4801-58-5 N-羟基哌啶 | CAS号145678-87-1 (+)-(3R,4S)-3,4... | CAS号74685-16-8 哌西那朵

Dimethyl 2,4-Dimethyl-4-Azaheptanedioate置于sodium体系中,用 Xylene 作为反应溶剂,化学反应 1.5H,以50%的收率获得产物1,3-二甲基-4-哌啶酮
参考文献:Potapov,V. M.; Gracheva,R. A.; Okulova,V. F.,Journal Of Organic Chemistry Ussr (English Translation),1989,Vol. 25,# 2.2,P. 311-316
标题:Potapov,V. M.; Gracheva,R. A.; Okulova,V. F.,Journal Of Organic Chemistry Ussr (English Translation),1989,Vol. 25,# 2.2,P. 311-316

专利信息

专利号:US-6867202-B1
优先权日:1997-06-25
标 题 :Treatment of insulin resistance
发明人：CARPINO PHILIP ALBERT; CHIU CHARLES KWOK-FUNG; PAN LYDIA CODETTA; LEFKER BRUCE ALLEN; TREADWAY JUDITH LEE; ZAWISTOSKI MICHAEL PAUL
权利人:PFIZER
摘要:This invention is directed to methods of treating insulin resistance in a mammal which comprise administering an effective amount of a compound of formula I, n n nwhere the variables are defined in the specification, or the stereoisomeric mixtures, diastereomerically enriched, diastereomerically pure, enantiomerically enriched or enantiomerically pure isomers, or the pharmaceutically acceptable salts and prodrugs thereof to said mammal. The compounds of formula I are growth hormone secretagogues and as such are useful for increasing the level of endogenous growth hormone. In another aspect this invention provides certain intermediates which are useful in the synthesis of the foregoing compounds and certain processes useful for the synthesis of said intermediates and th compounds of formula I. This invention is further directed to methods comprising administering to a human or other animal a combination of a functional somatostatin antagonist such as an alpha-2 adrenergic agonist and a compound of formula I.

专利号:RU-2044727-C1
优先权日:1993-04-27
标 题 :Method of synthesis alkylsubstituted 4-piperidones

专利号:CN-111422843-A
优先权日:2019-01-09
标 题 :Synthesis method of molecular sieve

专利号:CN-111422843-B
优先权日:2019-01-09
标 题:Synthesis method of molecular sieve