CAS: 3964-52-1; 4-Amino-2-Chlorophenol

上下游产品

CAS号619-08-9 2-氯-4-硝基酚 | CAS号872-50-4 N-甲基吡咯烷酮(NMP) | CAS号95-57-8 邻氯苯酚 | CAS号200710-27-6 2,2'-dichloro-4... | CAS号6657-05-2 Phenol,2-chloro... | CAS号855836-85-0 2-chloro-4,4'-a... | CAS号2050-16-0 4,4'-二羟基偶氮苯 | CAS号10468-17-4 3-氯苯基羟胺 | CAS号121-73-3 间氯硝基苯 | CAS号7664-93-9 硫酸 | CAS号524955-09-7 [3-氯-4-(吡啶-2-甲氧... | CAS号5930-28-9 2,6-二氯-4-氨基苯酚 | CAS号388082-78-8 二甲苯磺酸拉帕替尼 | CAS号3964-54-3 N-(3-氯-4-羟基苯基)乙酰胺 | CAS号76471-06-2 3-氯-4-[3-氯-5-(三... | CAS号695-99-8 2-氯-1,4-苯醌 | CAS号116714-46-6 氟酰脲 | CAS号34637-13-3 1-(3-Chloro-4-h... | CAS号26488-93-7 N-(5-氯-2-羟基苯基)乙酰胺 | CAS号116130-33-7 2-氯-4-碘苯酚

4,4'-二羟基偶氮苯置于盐酸,溶剂黄146,Tin(Ll) Chloride体系中,化学反应生成2-氯-4-氨基苯酚
参考文献:Hunter; Barnes,Journal Of The Chemical Society,1928,P. 2055
标题:Hunter; Barnes,Journal Of The Chemical Society,1928,P. 2055

专利信息

专利号:WO-2009080631-A2
优先权日:2007-12-21
标 题 :Chemo-enzymatic synthesis of a c-terminal aryl amide of an amino acid or peptide
发明人：QUAEDFLIEG PETER JAN LEONARD MARIO; NUIJENS TIMO; CUSAN CLAUDIA
权利人:DSM IP ASSETS BV; QUAEDFLIEG PETER JAN LEONARD MARIO; NUIJENS TIMO; CUSAN CLAUDIA
摘要:The present invention relates to a method for preparing an aryl amide, comprising reacting an aryl amine with a compound selected from N-protected amino acids and optionally N-protected peptides in the presence of a hydrolytic enzyme. The invention further relates to the use of a compound obtained in a method according to the invention in the manufacture of a diagnostic. In addition the invention relates to the use of a compound obtained in a method according to the invention as a substrate for a proteolytic enzyme.

专利号:US-7550510-B2
优先权日:2001-07-06
标 题 :Solid phase synthesis of arylretinamides
发明人：CURLEY JR ROBERT W; MERSHON SERENA M; BARNETT DEREK W; CLAGETT-DAME MARGARET; CHAPMAN JASON S
权利人:WISCONSIN ALUMNI RES FOUND
摘要:A solid phase synthetic method for preparing arylretinamides is provided. The method comprises reacting hexachloroacetone with a solvent-suspended resin-bound triphenylphosphine to provide a suspension comprising an activated chlorinating reagent; reacting retinoic acid with the activated chlorinating reagent to provide retinoyl chloride; adding pyridine and a select arylamine to the resulting mixture; and stirring the resulting mixture for a time and at a temperature sufficient for the select arylamine to react with the retinoyl chloride and provide the arylretinamide. Also provided, are select arylretinamides that can be prepared by the present method, and methods of using such arylretinamides to induce apoptosis in cancer cells.

专利号:WO-2013080218-A1
优先权日:2011-11-28
标 题 :Novel intermediates and process for the preparation of lapatinib and its pharmaceutically acceptable salts
发明人：LAHIRI SASWATA; GUPTA NITIN; SINGH HEMANT KUMAR; HANDA VISHAL; SANGHANI SUNIL
权利人:FRESENIUS KABI ONCOLOGY LTD
摘要:The present invention discloses novel intermediates and processes for the synthesis of Lapatinib and its pharmaceutically acceptable salts thereof.

专利号:US-2004102650-A1
优先权日:2001-07-06
标 题:Solid phase synthesis of arylretinamides

专利号:US-2003105164-A1
优先权日:2001-07-06
标 题 :Solid phase synthesis of arylretinamides

专利号:WO-03003987-A2
优先权日:2001-07-06
标题:Solid phase synthesis of arylretinamides