月桂酸乙烯酯,正己醇置于二氧化碳体系中,46.02 °C,8.81 Mpa 条件下,反应 3.5H,以97%的收率获得产物十二酸己酯 参考文献:Immobilization Of Lipase On Biocompatible Co-Polymer Of Polyvinyl Alcohol And Chitosan For Synthesis Of Laurate Compounds In Supercritical Carbon Dioxide Using Response Surface Methodology 标题:Immobilization Of Lipase On Biocompatible Co-Polymer Of Polyvinyl Alcohol And Chitosan For Synthesis Of Laurate Compounds In Supercritical Carbon Dioxide Using Response Surface Methodology 摘要:Biocompatible Co-Polymer Matrix Has Great Importance For Enzyme Immobilization And Subsequent Bio-Catalytic Applications To Synthesize Important Organic Moieties. Citronellyl Laurate Is A Fatty-Acid-Ester Having Pleasant Fruity Aroma And Widely Used As/in Emulsifier,Lubricant In Textile,Paint Or Ink-Additives,Surfactants,Perfumery And Food-Flavouring Ingredient. In Present Study,Burkholderia Cepacia Lipase (Bcl) Was Immobilized On Biodegradable Co-Polymer Of Chitosan (Chi) And Polyvinyl Alcohol (Pva). The Synthesized Bio-Catalyst {pva:Chi:Bcl (6:4:2.5)} Was Characterized By Sem,Tga,Lipase Assay And Protein-Content Analysis. This Biocatalyst Was Applied To Synthesize Citronellyl Laurate In Supercritical Carbon-Dioxide (Sc-Co2) Using Response Surface Methodology With Five-Factor-Three-Level Box-Behnken-Design To Optimize Reaction Parameters (Citronellol: 8.5 Mmol; Vinyl Laurate: 19.87 Mmol; Biocatalyst: 175.6 Mg; Temperature: 46.02 Degrees C; Pressure: 8.81 Mpa) Which Provided 94 +/-1.52% Yield. The Protocol Is Extended To Synthesize Various Important 12 Laurate Compounds With Excellent Yield (90-98%) And Noteworthy Recyclability (Upto Studied 5 Recycles). Interestingly,Immobilized Pva/chi/lipase Biocatalyst Showed 4-Fold Higher Bio-Catalytic Activity Than Free Lipase In Sc-Co2. Moreover,The Biocatalyst Activity Assessment Study Showed Remarkable Activity-Stability Of Immobilized Biocatalyst In Sc-Co2 Media As Compared To Free Enzyme. Thus,Present Protocol Demonstrated Potential Biocatalytic Applications For Synthesis Of Important Laurate Compounds With Excellent Recyclability In Sc-Co2 As Greener Biocatalyst And Reaction Medium. (C) 2015 Elsevier Ltd. All Rights Reserved. DOI:10.1016/j.Procbio.2015.04.019
专利号:US-2014255328-A1 优先权日:2013-03-11 标 题:Hydrothermal Synthesis of Zinc Phlogopite 发明人:MCGUIRE MEAGHAN CLARK; BULL IVOR; JOHNSON GEOFFREY MARK 权利人:BASF SE 摘要:This invention relates to a synthetically derived zinc phlogopite platelets, of superior platelet diameter, effect pigments comprising such synthetically derived platelets and methods of forming said substrates. More specifically the disclosure describes an improved hydrothermal synthesis of zinc phlogopite suitable as a platelets for interference pigments, barrier and flame retardant applications.
专利号:US-9597327-B2 优先权日:2005-05-25 标 题:Synthesis of (R)-N-methylnaltrexone 发明人:DOSHAN HAROLD D; PEREZ JULIO 权利人:PROGENICS PHARM INC 摘要:This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.
专利号:US-7722904-B2 优先权日:2007-11-01 标 题 :Compositions and methods for stimulating synthesis of pro-collagen or collagen and hyaluronic acid 发明人:SCHNEIDER LOUISE M; PUSATERI DONALD J; LA TOM Q 权利人:ACCESS BUSINESS GROUP INT LLC 摘要:A method for improving the appearance, texture and/or moisture of skin comprising administering a composition comprising Chia Seed oil, Opuntia ficus Indica extract, or both to stimulate collagen or hyaluronic acid synthesis, or decrease Interleukin-1b synthesis, in the skin.
专利号:US-9757317-B2 优先权日:2014-09-12 标题 :Cosmetic compositions and methods for inhibiting melanin synthesis 发明人:LAUGHLIN II LEO TIMOTHY; HAKOZAKI TOMOHIRO; GUPTA SHIKHAR 权利人:PROCTER & GAMBLE 摘要:A cosmetic composition suitable for topical application, for example, is provided. In some examples, the cosmetic composition may include bisabolol, undecylenoyl phenylalanine and/or hexyldecanol, and a material selected from the group consisting of ethyl palmitate, stearyl alcohol, bis (2-ethylhexyl) adipate, bis (2-ethylhexyl) maleate, 5-pentadecanol, 1-stearoyl-rac-glycerol, bis (2-ethylhexyl) sebacate, and mixtures thereof. A method of reducing the synthesis of melanin by using the cosmetic compositions is also disclosed herein.
专利号:US-9498420-B2 优先权日:2013-05-01 标 题:Cosmetic compositions and methods for inhibiting melanin synthesis 发明人:LAUGHLIN II LEO TIMOTHY; HAKOZAKI TOMOHIRO; TANAKA SHUHEI 权利人:PROCTER & GAMBLE 摘要:A cosmetic composition suitable for topical application, for example, is provided. In some examples, the cosmetic composition may include batyl alcohol, undecylenoyl phenylalanine, hexyldecanol, and bisabolol. A method of reducing the synthesis of melanin by using the cosmetic compositions is also disclosed herein.
专利号:US-10799441-B2 优先权日:2011-06-06 标题:Skin treatments containing pyrroloquinoline quinone (PQQ) esters and methods of preparation and use thereof 发明人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C 权利人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C; PCR TECH HOLDINGS LC 摘要:The present invention relates to cosmetic or dermatological compositions containing PQQ or its esters, methods of treating or promoting skin changes by topical application of these compositions, and methods of synthesis of PQQ esters. The PQQ ester-containing compositions of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the PQQ esters of the present invention have an antioxidant effect that is useful in treating a skin change.
摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118 摘要:International Journal of Toxicology 34(Suppl.2):5-69, 2015 参考文献:10.1007/s00359-008-0321-7 摘要:Barth FG, Hrncir M, Jarau S. Signals and cues in the recruitment behavior of stingless bees (Meliponini). J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2008 Apr;194(4):313–27. doi: 10.1007/s00359-008-0321-7. 参考文献:10.1007/s00436-011-2436-y 摘要:Martínez-de la Puente J, Rivero-de Aguilar J, Del Cerro S, Argüello A, Merino S. Do secretions from the uropygial gland of birds attract biting midges and black flies Parasitol Res. 2011 Dec;109(6):1715–8. doi: 10.1007/s00436-011-2436-y.