CAS: 30462-35-2; (2R,2'R,3R,3'R)-2,2'-(3,4,6-Trihydroxy-5-Oxo-5H-Benzo[7]Annulene-1,8-Diyl)Bis(5,7-Dihydroxychroman-3,2-Diyl) Bis(3,4,5-Trihydroxybenzoate)

该化合物是主要在黑茶中发现的茶叶酸盐氧化过程产生的一种多酚化合物,由于它的胆碱酯酶,它具有很强的抗氧化特性,它强化了自由的激进清扫和金属切热.TF3在调制细胞信号路径方面表现出潜力,包括NF-B和MAPK, 有助于抗炎和抗癌效应.它的结构性稳定性和生物利用率使它成为营养和药物研究的焦点.研究表明TF3可能通过抑制LDL氧化和改善内皮功能来支持心血管健康.它作为抗氧化剂和生物活性调制剂的双重作用强调了它在功能食物和治疗应用中的效用.

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CAS号1257-08-5 表儿茶素没食子酸酯 | CAS号989-51-5 (-)-表没食子儿茶素没食子酸酯

合成工艺路线路线简述

    📜(-)-表儿茶素没食子酸酯,(-)-表没食子儿茶素没食子酸酯置于polyphenol Oxidase体系中,化学反应 6.0H,反应生成 8-姜酚
    参考文献:Benzotropolone Derivatives And Modulation Of Inflammatory Response
    标题:Benzotropolone Derivatives And Modulation Of Inflammatory Response
    摘要:本发明提供了一种由通式表示的新型苯并三酮衍生物: 包括新茶黄素b和egcgca.本发明的苯并三酮衍生物是有效的抗氧化剂和抗炎药物.本发明还提供了一种高产率合成苯并三酮化合物的新方法,以及使用含有苯并三酮的化合物治疗炎症症状的方法.

    专利信息


    专利号:US-2014357576-A1
    优先权日:2013-05-31
    标题:Methods for enhancement of muscle protein synthesis
    发明人:BREUILLE DENIS; STELLINGWERFF TRENT; MOORE DANIEL RYAN; OFFORD CAVIN ELIZABETH ANN; PHILLIPS STUART MARTIN
    权利人:NESTEC SA
    摘要:The present disclosure provides methods for enhancing muscle protein synthesis in an individual in need of same. Specifically, the present disclosure provides methods for enhancing muscle protein synthesis by enhancing myofibrillar muscle protein synthesis. The method includes administering to the individual a mixed macronutrient composition having (i) an amount of whey protein that is not capable of enhancing myofibrillar protein synthesis when ingested by itself and (ii) free leucine. The composition comprises at least about 5.0 g total leucine per dose.

    专利号:US-2014294788-A1
    优先权日:2013-03-26
    标 题 :Methods for enhancing muscle protein synthesis following concurrent training
    发明人:BAILEY DAVID MARK; ZALTAS ERIC SCOTT; MOORE DANIEL RYAN; STELLINGWERFF TRENT
    权利人:NESTEC SA
    摘要:The present disclosure provides methods for enhancing muscle protein synthesis following physical exertion. In a general embodiment, a method for enhancing muscle protein synthesis following physical exertion is provided and includes administering to an individual a composition comprising from about 15 to about 35 g protein immediately following concurrent training. Programs for enhancing muscle adaptation resulting from concurrent training are also provided. The programs include providing a composition comprising from about 15 to about 35 g protein; and providing guidelines for consumption including a recommendation of the amount of the composition to consume immediately following concurrent training.

    专利号:CN-104651426-A
    优先权日:2015-02-13
    标 题 :Method for enzymatic synthesis of theaflavin TF by virtue of tea polyphenol oxidase isoenzyme PPO1

    专利号:WO-2021189018-A9
    优先权日:2020-03-20
    标 题 :Methods of treating viral infections using inhibitors of nucleotide synthesis pathways

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    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Theaflavin-3,3′-Digallate Suppresses Human Ovarian Carcinoma OVCAR-3 Cells by Regulating the Checkpoint Kinase 2 and p27 kip1 Pathways Ying Gao, Junfeng Yin, Youying Tu, Yi Charlie Chen Molecules. 2019 Feb; 24(4): 673. Published online 2019 Feb 14. doi: 10.3390/molecules24040673 RANKIN, YOUYING TU, YI CHARLIE CHEN Int J Oncol. 2016 Jan; 48(1): 281–292. Published online 2015 Nov 20. doi: 10.3892/ijo.2015.3257 2015; 10(11): e0143158. Published online 2015 Nov 18. doi: 10.1371/journal.pone.0143158 Rankin, Yon Rojanasakul, Youying Tu, Yi Charlie Chen Int J Mol Sci. 2018 Jan; 19(1): 117. Published online 2018 Jan 2. doi: 10.3390/ijms19010117 Isaacs, Weimin Xu Antimicrob Agents Chemother. 2013 Aug; 57(8): 3806–3814. doi: 10.1128/AAC.00659-13 PMCID: PMC3719710

    合成参考文献


    摘要:https://pubs.acs.org/doi/abs/10.1021/acs.analchem.7b01709
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