CAS: 22120-39-4; N,N-Dimethyl-2-(5-Methyl-1H-Indol-3-yl)Ethanamine

化学文摘社编号22120-39-4,化学化合物,属于无花生衍生物类别,具有核心无花果结构,由双环化合物组成,由苯环组成,与烧花圈相连,在氮和碳位置上存在三个甲基组,有助于其独特的特性,影响其溶解性和再活性.该化合物经常被研究其潜在的生物活动,包括对...

结构式图片

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号19718-92-4 4-(二甲氨基)丁醛缩二甲醇 | CAS号637-60-5 4-甲基苯肼盐酸盐 | CAS号1821-47-2 5-甲基色胺 | CAS号74-88-4 碘甲烷 | CAS号50-00-0 甲醛

合成工艺路线路线简述

    📜4-二甲胺基丁醛缩二甲醇,4-甲基苯肼盐酸盐置于硫酸体系中,化学反应 2.0H,以89%的收率获得5-甲基-N,N-二甲基色胺
    参考文献:Improved Fischer Indole Reaction For The Preparation Of N,N-Dimethyltryptamines: Synthesis Of L-695,894,A Potent 5-Ht1D Receptor Agonist
    标题:Improved Fischer Indole Reaction For The Preparation Of N,N-Dimethyltryptamines: Synthesis Of L-695,894,A Potent 5-Ht1D Receptor Agonist
    摘要:
    Doi:10.1021/jo00092A046

    海关参考信息

    专利信息


    专利号:EP-1751104-B1
    优先权日:2004-01-28
    标题:Synthesis methods and intermediates for the manufacture of rizatriptan

    其他信息查阅

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    实用工具

    ⚠️全国化工行业净网倡议书
    📋制造商识别码
    📖 海关编码查询
    📝MSDS生成器

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:A Facile Procedure For Synthesis Of 3-[2-(N,N-Dialkylamino)Ethyl]-3-Fluorooxindoles By Direct Fluorination Of N,N-Dialkyltryptamines
    作者:Takayuki Seki,Tomoya Fujiwara,Yoshio Takeuchi |发布日期:2011.3
    摘要:A Practical Procedure For The Synthesis Of 3-Fluorooxindole Derivatives Having Basic Amine Moieties Was Developed, Which Involves Selectfluor™-Mediated Oxidative Fluorination Of N,N-Dialkyltryptamines In The Presence Of Lewis Acid. This Procedure Was Applied To An Antimigraine Drug, Rizatriptan, To Afford The Corresponding 3-Fluorooxindole, Which Is A Potential Fluorine-Containing Drug Candidate.

    合成参考文献


    摘要:Psychopharmacologia, 16(385), 1970 []
    摘要:U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals., NX#01632
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知