CAS: 220239-64-5; 2,4,6-Trifluorobenzene-1-Sulfonyl Chloride
该化合物是在核生殖替代反应中,使其成为有机合成中有价值的中间体,特别是在准备磺酰胺和其他磺酰衍生物时.氟原子的存在会增强其电益性和可能影响物理特性,例如溶液和沸点.此外,2,4,6-三氟苯基氯化物对水体敏感,应谨慎处理,因为它在水解过程中会释放有毒气体.在与该化合物合作时,适当的安全防范措施,包括使用个人防护设备和在烟雾罩中工作,至关重要.
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报上下游产品
CAS号372-38-3 1,3,5-三氟苯合成工艺路线路线简述
📜1,3,5-三氟苯置于氯磺酸体系中,化学反应生成2,4,6-三氟苯磺酰氯
参考文献:Novel Halogenated Sulfonamides Inhibit The Growth Of Multidrug Resistant Mcf-7/adr Cancer Cells
标题:Novel Halogenated Sulfonamides Inhibit The Growth Of Multidrug Resistant Mcf-7/adr Cancer Cells
摘要:In This Report,We Describe The Synthesis Of Halogenated Benzenesulfonamide Compounds And Their Ability To Inhibit The Growth Of Hela,Mcf-7 And Mcf-7/adr Tumor Cells In Vitro. The Multidrug Resistance (Mdr) Phenotype Of Certain Cells Does Not Affect Their Sensitivity To These Compounds. These Agents Belong To A Family Of Compounds Previously Shown To Bind Irreversibly To Cysteine-239 Of Beta-Tubulin. Consistent With This Mechanism Of Action,The Cytotoxicities Of These Compounds Appear To Correlate With Their Ability To Undergo Nucleophilic Aromatic Substitution. (C) 1999 Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/s0960-894X(99)00276-0
专利信息
专利号:KR-102144626-B1
优先权日:2017-11-14
标 题:A method for synthesis of benzene sulfonate derivatives
专利号:KR-20190105493-A
优先权日:2017-11-14
标题 :A method for synthesis of benzene sulfonate derivatives
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考DOI号:10.1016/S0960-894X(99)00276-0
📝 需求与反馈
尽可能描述清楚需求与问题信息
