CAS: 1453-58-3; 3-Methylpyrazole

相似化合物

67-51-6 23486-70-6 36650-74-5

上下游产品

CAS号107-06-2 1,2-二氯乙烷 | CAS号5436-21-5 4,4-二甲氧基-2-丁酮 | CAS号460-12-8 丁二炔 | CAS号821-10-3 1,4-二氯-2-丁炔 | CAS号1568-20-3 5-methyl-2-pyra... | CAS号91272-98-9 1-(PYRROLIDIN-1... | CAS号74-88-4 碘甲烷 | CAS号936250-20-3 3-甲基吡唑-4-硼酸频那醇酯 | CAS号186551-70-2 3-甲基-1H-吡唑-1-羧酸叔丁酯 | CAS号27301-77-5 1-(4-氯苯基)-3-甲基-1H-吡唑 | CAS号873-50-7 3-甲基吡唑-1-甲酰胺 | CAS号5334-39-4 3-甲基-4-硝基吡唑 | CAS号694-48-4 1,3-二甲基吡唑 | CAS号694-31-5 1,5-二甲基-1H-吡唑 | CAS号1128-54-7 3-甲基-1-苯基吡啶 | CAS号6831-91-0 5-甲基-1-苯基-1H-吡唑 | CAS号5334-40-7 4-硝基吡唑-3-甲酸

丁二炔置于一水合肼体系中,化学反应生成3-甲基吡唑
参考文献:Preparation Of 3(5)-Methylpyrazoles
标题:Preparation Of 3(5)-Methylpyrazoles
摘要:从二乙炔和肼制备甲基吡唑的过程中,通过吸收将二乙炔从裂解气中去除,然后与肼反应.

专利信息

专利号:US-11479577-B2
优先权日:2016-05-18
标题:Intermediates for the synthesis of bile acid derivatives, in particular of obeticholic acid
发明人：WEYMOUTH-WILSON ALEXANDER; KOMSTA ZOFIA; WALLIS LAURA; EVANS TIMOTHY; DAVIES IEUAN; OTTER CARL; BATCHELOR RHYS
权利人:NZP UK LTD
摘要:The present invention relates to compounds which are intermediates in the synthesis of bile acid derivatives with pharmacological activity. The invention relates to compounds of general formula (I):wherein:, R1, R2, R3, R4, R5, R6 and Y are as defined herein.The compounds are intermediates in the synthesis of synthetic bile acids which are useful in the treatment of conditions such as liver disease. In addition, the invention relates to a method of synthesizing these intermediates and a method of preparing obeticholic acid and obeticholic acid analogues from the compounds of the invention.

专利号:US-8637695-B2
优先权日:2011-12-30
标 题:Synthesis of organohalosilane monomers from conventionally uncleavable Direct Process Residue
发明人：LEWIS KENRICK MARTIN; NEELY JOHN DAVID
权利人:LEWIS KENRICK MARTIN; NEELY JOHN DAVID; MOMENTIVE PERFORMANCE MAT INC
摘要:Disclosed herein is a catalytic process for the synthesis of organohalosilane monomers from tetraorganodihalodisilanes and other compounds that are not cleaved during the conventional hydrochlorination of Direct Process Residue. The process is characterized by the use of a catalyst containing (1) one or more heterocyclic amines and/or one or more heterocyclic ammonium halides, and (2) one or more quaternary Group 15 onium compounds.

专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-11848117-B2
优先权日:2017-12-06
标题:Thin and uniform silver nanowires, method of synthesis and transparent conductive films formed from the nanowires
发明人：HU YONGXING; LI YING-SYI; YANG XIQIANG; ANG JING SHUN; VIRKAR AJAY
权利人:C3 NANO INC
摘要:Highly uniform and thin silver nanowires are described having average diameters below 20 nm and a small standard deviation of the diameters. The silver nanowires have a high aspect ratio. The silver nanowires can be characterized by a small number of nanowires having a diameter greater than 18 nm as well as with a blue shifted narrow absorption spectrum in a dilute solution. Methods are described to allow for the synthesis of the narrow uniform silver nanowires. Transparent conductive films formed from the thin, uniform silver nanowires can have very low levels of haze and low values of ΔL*, the diffusive luminosity, such that the transparent conductive films can provide little alteration of the appearance of a black background.

专利号:US-6051704-A
优先权日:1996-07-22
标题:Synthesis of macrocyclic tetraamido-N ligands
发明人：GORDON-WYLIE SCOTT W; COLLINS TERRENCE J
权利人:UNIV CARNEGIE MELLON
摘要:New synthetic methods for the preparation of macrocyclic amido-N donor ligands are provided. The primary method of the present invention involves in general only two synthetic steps. In the first step, an α or β amino carboxylic acid is allowed to react with an optimal (approximately stoichiometric) amount of an activated malonate or oxalate derivative with mild heating. Upon completion of the double coupling reaction, hydrolysis of the reaction mixture yields a diamide containing intermediate (a macro linker). In the second step, stoichiometric amounts of a diamine, preferably an orthophenylene diamine, are added to the macro linker intermediate in the presence of a coupling agent and heat. This second double coupling reaction, is allowed to proceed for a period of time sufficient to produce a macrocyclic tetraamido compound. The substituent groups on the α or β amino carboxylic acid, the malonate, and the aryl diamine may all be selectively varied so that the resulting tetraamido macrocycle can be tailored to specific desired end uses. The macrocyclic tetraamide ligand may then be complexed with a metal, such as a transition metal, and preferably the middle and later transition metals, to form a robust chelate complex suitable for catalyzing oxidation reactions.

专利号:US-10766921-B2
优先权日:2016-05-18
标 题 :Process and intermediates for the 6,7-alpha-epoxidation of steroid 4,6-dienes
发明人：WEYMOUTH-WILSON ALEXANDER; KOMSTA ZOFIA; WALLIS LAURA; EVANS TIMOTHY
权利人:NZP UK LTD
摘要:The invention relates to a process for preparing a compound of general formula (Ia): wherein R2, Y, R4 and R5 are as defined herein, wherein the epoxidation is conducted using an oxidant and methyltrioxorhenium as a catalyst (MeReO3). The invention also relates to certain compounds per se. The compounds are intermediates in the synthesis of synthetic bile acids.