CAS: 112811-71-9; Ethyl 1-Cyclopropyl-6,7-Difluoro-8-Methoxy-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate

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专利信息

专利号:US-8198451-B2
优先权日:2006-11-13
标题 :Process for the synthesis of moxifloxacin hydrochloride
发明人：RAO DHARMARAJ RAMACHANDRA; KANKAN RAJENDRA NARAYANRAO; PATHI SRINIVAS LAXMINARAYAN; PUPPALA RAVIKUMAR; GANGRADE MANISH; KANATHALA SHASHIREKHA
权利人:RAO DHARMARAJ RAMACHANDRA; KANKAN RAJENDRA NARAYANRAO; PATHI SRINIVAS LAXMINARAYAN; PUPPALA RAVIKUMAR; GANGRADE MANISH; KANATHALA SHASHIREKHA; CIPLA LTD
摘要:A new polymorph of moxifloxacin hydrochloride is described, together with a method for making the polymorph. In addition, new intermediates in the formation of moxifloxacin hydrochloride are described, having formulas (1) and (II):

专利号:AU-2007320997-B2
优先权日:2006-11-13
标题:Process for the synthesis of moxifloxacin hydrochloride

专利号:US-2010152229-A1
优先权日:2006-11-13
标题:Process for the Synthesis of Moxifloxacin Hydrochloride

专利号:US-8207339-B2
优先权日:2010-03-19
标 题 :Process for preparing Moxifloxacin and salts thereof
发明人：CASTELLIN ANDREA; PADOVAN PIERLUIGI; JIAGENG LIU; ZHOU YIBO; FENG LIN
权利人:CASTELLIN ANDREA; PADOVAN PIERLUIGI; JIAGENG LIU; ZHOU YIBO; FENG LIN; ITALIANA SINT SPA
摘要:The present invention relates to a process for the synthesis of Moxifloxacin of Formula (I) and salts thereof n nby means of a process providing the coupling reaction of 1-cyclopropril-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo -3-quinolinic acid or ester thereof with (4aS, 7aS) -octahydro-1H-pyrrole[3,4-b]pyridine using a magnesium salt.

专利号:CA-2669427-A1
优先权日:2006-11-13
标 题:Process for the synthesis of moxifloxacin hydrochloride

专利号:EP-2089388-B1
优先权日:2006-11-13
标 题:Process for the synthesis of moxifloxacin hydrochloride