CAS: 98446-49-2; 2,4-Dichloro-5-Methoxyaniline

上下游产品

CAS号7206-70-4 4-氨基-5-氯-2-甲氧基苯甲酸 | CAS号65182-98-1 N-(2,4-二氯-5-甲氧基... | CAS号67669-19-6 N-(2,4-二氯-5-羟基苯基)乙酰胺 | CAS号621-42-1 3'-羟基乙酰苯胺 | CAS号380843-75-4 伯舒替尼 | CAS号39489-79-7 2,4-二氯-5-氨基苯酚 | CAS号846023-24-3 2-氰基-N-(2,4-二氯-... | CAS号2387-23-7 N,N’-二环己基脲 | CAS号338967-87-6 3-(2,4-二氯-5-甲氧基... | CAS号50375-04-7 1,5-dichloro-2,... | CAS号622369-46-4 4-(2,4-二氯-5-甲氧基... | CAS号380844-49-5 7-(3-氯丙氧基)-4-[(...

N-(2,4-二氯-5-羟基苯基)乙酰胺置于盐酸,Potassium Carbonate体系中,用 甲醇,水,丙酮 作为反应溶剂,化学反应 7.0H,反应生成 2,4-二氯-5-甲氧基苯胺
参考文献: A Process For The Preparation Of Bosutinib[fr] Procédé De Préparation De Bosutinib
标题: A Process For The Preparation Of Bosutinib[fr] Procédé De Préparation De Bosutinib
摘要:本发明提供了一种改进的制备波苏替尼及其中间体2-氰基-N-(2,4-二氯-5-甲氧基苯基)乙酰胺的方法.

专利信息

专利号:US-7365197-B2
优先权日:2000-12-29
标题 :Method for the regioselective preparation of substituted benzo[g]quinoline-3-carbonitriles and benzo[g]quinazolines
发明人：BERGER DAN MAARTEN; BIRNBERG GARY HAROLD; WANG YANONG
权利人:WYETH CORP
摘要:This invention relates to a method for the regioselective synthesis of 4,6,7,8-substituted benzo[g]quinoline-3-carbonitriles and 4,6,7,8-substituted benzo[g]quinazolines as well as intermediates thereof. The compounds derived from this invention are useful for the treatment of a variety of diseases that are a result of deregulation of these PTK's, and more specifically, are anti-cancer agents and are useful for the treatment of cancer in mammals. In addition, the compounds derived from this invention are useful for the treatment of polycystic kidney disease in mammals.

专利号:WO-2017135901-A1
优先权日:2016-02-05
标题 :Heterocyclic compounds, methods of synthesis and uses thereof
发明人：CHUA BOON TIN; KERI GYORGY; ORFI LASZLO; Németh Gábor; WÃ?CZEK FRIGYES; Varga Zoltán; MARKO PETER
权利人:AGENCY SCIENCE TECH & RES; VICHEM CHEMIE RES LTD
摘要:The present invention relates to 3-quinolinecarbonitrile compounds of formula (I) disclosed herein, methods for their synthesis, and uses thereof. Advantageously, the disclosed heterocyclic compounds may demonstrate enhanced efficacy in antitumor properties. Hence, the present disclosure also relates to the use of the disclosed 3-quinolinecarbonitrile compounds or pharmaceutical compositions thereof in cancer treatment.

专利号:US-7579356-B2
优先权日:2005-05-04
标 题:Thia-tetraazaacenaphthylene kinase inhibitors
发明人：BATTISTA KATHLEEN A; BIGNAN GILLES C; CONNOLLY PETER J; HAYDEN STUART; JOHNSON SIGMOND G; LIN RONGHUI; PANDEY NIRANJAN B; POWELL MARK T
权利人:JANSSEN PHARMACEUTICA NV
摘要:The present invention is directed to novel thia-tetraazaacenaphthylene compounds of Formula (I): n nand pharmaceutically acceptable forms thereof and their synthesis and use as inhibitors of ATP-protein kinase interactions.