CAS: 95-53-4; O-Toluidine

上下游产品

pyridine N,N'-di(o-tolyl)thiourea indole 2-methylchlorobenzene2-(2-tolylamino)ethan-1-ol N,N-bis-(2-hydroxy-ethyl)-o-toluidineN,N-bis-(2-hydroxy-ethyl)-o-toluidine o-toluidino-ethanethiol2-o-toluidino-ethanethiol 1-(2-methylphenyl)pyrrolidine

盐酸丙胺卡因 以 甲醇 作为反应溶剂,化学反应 72.0H,反应生成 邻甲苯胺
参考文献:Determination Of Prilocaine Hcl In Pharmaceutical Preparations By Gc-Ms Method
标题:Determination Of Prilocaine Hcl In Pharmaceutical Preparations By Gc-Ms Method
摘要:采用气相色谱-质谱联用(gc-Ms)法开发并验证了一种新的分析方法,用于测定药物制剂中的盐酸丙胺卡因.该方法使用盐酸利多卡因作为内标(is),在hp-5Ms毛细管柱上进行操作.盐酸丙胺卡因的浓度在40-1000 Ng/ml范围内时,校准曲线呈线性(r = 0.999).检测限(lod)和定量限(loq)分别为15和31 Ng/ml.日内和日间相对标准偏差(rsd)和相对误差(re)百分比值分别不超过3.4%和3.5%.通过该方法测定,在自动进样器中储存72小时后形成的邻甲苯胺.所开发的方法可以直接,简便地应用于采用内标法测定药物制剂中未经衍生化的盐酸丙胺卡因.
DOI:10.14233/ajchem.2014.17150

专利信息

专利号:US-5824472-A
优先权日:1986-03-24
标 题 :Process for the synthesis of sugar nucleotides using recombinant-DNA methods
发明人：BETLACH MICHAEL R; DOHERTY DANIEL H; VANDERSLICE REBECCA W
权利人:MONSANTO CO
摘要:A recombinant-DNA mediated method for the synthesis of sugar nucleotides is disclosed. This method utilizes portable DNA sequences capable of directing the microbial synthesis of various enzymes that catalyze the synthesis of sugar nucleotides, including UDP-glucose, UDP-glucuronic acid and GDP-mannose. The sugar moieties of these sugar nucleotides may subsequently be incorporated into industrially-useful polysaccharides such as xanthan gum. It has been found that vectors containing the portable DNA sequences described herein are capable both of causing sugar nucleotide production in microorganisms previously incapable of such synthesis and of causing increased sugar nucleotide production in organisms capable of synthesizing small quantities of these compounds. In particular, plasmids pAS7, pAS9 and pTS13 are disclosed. These plasmids are capable of directing sugar nucleotide synthesis in various hosts, including Xanthomonas sp. such as X. campestris and other organisms such as E. coli and various Pseudomonas sp.

专利号:US-6515039-B1
优先权日:1998-08-28
标 题:Method for the parallel and combinatory synthesis of compounds bound to a continuous polymeric solid phase supporting material
发明人：ULBRICHT MATHIAS; VOLKMER-ENGERT RUDOLF; GERMEROTH LOTHAR; WENSCHUH HOLGER
权利人:POLY AN GMBH
摘要:The invention relates to a method for the parallel and combinatory synthesis of compounds bound to a continuous polymeric solid phase supporting material. According to the method, a continuous polymeric solid phase supporting material is prepared, the material comprising a matrix of a supporting polymeric material and graft copolymer chains covalently bound to the supporting matrix, the graft copolymer chains having reactive groups being able to react with organic compounds, thereby forming spatially defined reaction sites. The method then comprises the sequential spotting of synthesis building blocks or reagents at the various reaction sites on the continuous solid phase supporting material to yield a substrate library of compounds bound to the solid phase supporting material, whereby each reaction site on the continuous solid phase supporting material determines the composition of the synthesized compound, which is bound directly on the supporting matrix via the reactive groups of the graft polymer chain.

专利号:US-7692016-B2
优先权日:2005-11-25
标 题 :Process for the synthesis of quinoline derivatives
发明人：MADUGULA SREE RAMA MURTY; THALLAPELLY SWAMY; BANDARUPALLY JYOTHIRMAI; YADAV JHILLU SINGH
权利人:COUNCIL SCIENT IND RES
摘要:The present invention provides an improved process for the synthesis of quinoline derivatives. More particularly the present invention provides an improved and economical process for the synthesis of quinoline derivatives by the reaction of aniline/substituted anilines using two different catalysts, ferric chloride and zinc chloride in a one-pot set up reaction.

专利号:US-10597358-B2
优先权日:2015-01-16
标题:Synthesis of carbamate or urea compounds
发明人：VAN DER HEIJDEN ANTONIUS EDUARD DOMINICUS MARIA; VAN GEEST ERIK; VAN DEN ELSHOUT JOS JOHAN MATTHIJS HUGO
权利人:TNO
摘要:The invention pertains to the synthesis of carbamate and urea compounds. In particular the invention is directed to the synthesis of carbamate and urea compounds which may be used in the production of compounds that are used to stabilize nitrocellulose. The method of the invention comprises preparing a carbamate or urea derivative comprising reacting an amine and a carbonate or carbamate in the presence of an ionic liquid.

专利号:US-7713446-B2
优先权日:2004-06-28
标 题:Synthesis of nanofibers of polyaniline and substituted derivatives
发明人：EPSTEIN ARTHUR J; CHIOU NAN-RONG
权利人:OHIO STATE UNIVERISTY
摘要:Novel, simple methods are presented directed to the synthesis of nanofibers of polyaniline and substituted derivatives. The production of these fibers is achieved via various methods by controlling the concentration of aniline monomer or substituted aniline derivatives or an oxidant in the reaction medium and maintaining said concentration at a level much lower than conventional polyaniline synthesis methods. Methods are disclosed relating to the use of a permeable membrane to control the release of a monomer and/or oxidant as well as a bulk polymerization method.

专利号:WO-2025134140-A1
优先权日:2023-12-19
标题:A method for the synthesis of substituted anthranilic amide compounds, intermediates and salts thereof
发明人：MALVIYA NITIN JAIKANT; SINGH VIPENDER; SHAH JIGARKUMAR HARKISHANDAS; KALE MANOJ GANPAT; KAVITAKE SANTOSH GIRIDHAR; BORHADE AJIT SAHEBRAO; KLAUSENER ALEXANDER G M
权利人:PI INDUSTRIES LTD
摘要:The present invention discloses a method for the synthesis of compounds of formula (I) or a salt thereof, wherein, R is selected from hydrogen, halogen, cyano, C1-C12 alkyl, C1-C12 haloalkyl, C1-C12 alkoxy, C1-C12 haloalkoxy, or C3-C8 cycloalkyl; R4 is selected from hydrogen, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, C1-C12 haloalkyl, C2-C12 haloalkenyl, C2-C12 haloalkynyl, C1-C12 alkoxy, C1-C12 haloalkoxy, C3-C8 cycloalkyl, or C3-C8 cycloalkyl-C1-C10 alkyl; and n represents an integer selected from 0-4. The method further comprises the synthesis of an anthranilic diamide compound of formula (A).