CAS: 62476-58-8; 2-Chloro-3-(Trifluoromethyl)Aniline

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Tert-Butyl 2-Chloro-3-(Trifluoromethyl)Phenylcarbamate 908123-86-4

Tert-Butyl 2-Chloro-3-(Trifluoromethyl)Phenylcarbamate,Hydrochloric Acid Diethyl Ether 以 乙醚 作为反应溶剂,化学反应 24.0H,反应生成 2-氯-3-三氟甲基苯胺,
参考文献:Use Of Selective P2X7 Receptor Antagonists
标题:Use Of Selective P2X7 Receptor Antagonists
摘要:本发明涉及使用公式i中的选择性p2X7受体拮抗剂,或其药学上可接受的盐或前药,其中d,R1和r2如权利要求书1中定义的,用于治疗神经病理性疼痛,慢性炎性疼痛,炎症,神经退行性疾病以及促进神经再生.

专利信息

专利号:US-5420351-A
优先权日:1993-11-25
标题 :Aromatic diamine compounds
发明人：SUZUKI OSAMU; YOKOMIZO HIROHIKO; ARAI TAKESHI; NAKAJIMA NAMIKO
权利人:NISSHIN SPINNING
摘要:An aromatic diamine compound represented by formula (1): ##STR1## wherein R 1 and R 2 , which may be the same or different, are each a hydrogen atom or a lower alkyl group; and an aromatic diamine compound useful as an intermediate for the synthesis of the above compound (1), represented by formula (2): ##STR2## The compound (1) alleviates the problems of the prior art, and is unlikely to cause crystallization by heat and has a melting point and a glass transition temperature both higher than those of conventional compounds.