CAS: 60827-45-4; (2S)-(+)-3-Chloropropane-1,2-Diol

相似化合物

57090-45-6 136917-95-8 4151-97-7

上下游产品

CAS号106-89-8 环氧氯丙烷 | CAS号24423-98-1 1-chloro-3-hydr... | CAS号67843-74-7 (S)-(+)-环氧氯丙烷 | CAS号107-05-1 氯丙烯 | CAS号78692-88-3 (S)-1,2-Diaceto... | CAS号96-24-2 3-氯-1,2-丙二醇 | CAS号869-50-1 1-CHLOROMETHYL-... | CAS号444335-16-4 (5R)-3-(4-溴-3-氟... | CAS号60456-23-7 (S)-缩水甘油 | CAS号113826-06-5 (R)-对甲苯磺酸缩水甘油酯 | CAS号115314-14-2 3-硝基苯磺酸(|S|)-缩水甘油基酯

3-氯丙烯 以 Na4E(Cn)610H2,水,乙酸乙酯,甲苯 作为反应溶剂,以66.8%的收率获得产物(S)-3-氯-1,2-丙二醇
参考文献:Electrocatalytic Asymmetric Dihydroxylation Of Olefinic Compounds
标题:Electrocatalytic Asymmetric Dihydroxylation Of Olefinic Compounds

专利信息

专利号:US-4313008-A
优先权日:1976-09-30
标题:Synthesis of S-3-chloro-1,2-propanediol
发明人：JONES HAYDN F
权利人:TATE & LYLE LTD
摘要:The S-enantiomer of 3-chloro-1,2-propanediol is prepared by reaction of a chlorodeoxy-D-saccharide having the partial structure. (I) to cleave the glycol, reduce the aldehyde so formed to an alcohol, and hydrolyse the alcohol under mild acidic conditions.

专利号:JP-2009235037-A
优先权日:2008-03-28
标 题 :Method for the synthesis of chiral epichlorohydrin

专利号:US-4814506-A
优先权日:1986-08-26
标题:Process for preparing 3 halogeno-2-hydroxypropyltrimethylammonium halide
发明人：KATAYAMA KAZUHIKO; HAMAGUCHI SHIGEKI; KOGAME YOSHIKAZU; OHASHI TAKEHISA; WATANABE KIYOSHI
权利人:KANEGAFUCHI CHEMICAL IND
摘要:A process for preparing 3-halogeno-2-hydroxy-propyltrimethylammonium halide or especially one having the (S)-configuration, which comprises reacting 2,3-dihydroxypropyltrimethylammonium halide or one having the (S)-configuration, which is obtained by reacting (R)-3-halogeno-1,2-propanediol with trimethylamine, with a halogenating reagent. According to the present invention, 3-halogeno-2-hydroxypropyltrimethylammonium halide or one having the (S)-configuration, which is a useful intermediate for the synthesis of carnitine or especially (l)-carnitine, can be obtained economically, efficiently and easily.

专利号:CA-1111866-A
优先权日:1976-09-30
标题 :Synthesis of s-3-chloro-1, 2-propanediol

专利号:GB-1553602-A
优先权日:1976-09-30
标题 :Synthesis of s-3-chloro-1,2-propanediol

专利号:US-6639087-B2
优先权日:2001-08-22
标题:Kinetic resolution method
发明人：LARROW JAY F; JASMIN SERGE; LIU YI; DI MARE MARCELLO
权利人:RHODIA PHARMA SOLUTIONS INC
摘要:A method for stereoselective chemical synthesis, includes the steps of: (A) reacting a nucleophile and chiral or prochiral cyclic subtrate, said substrate comprising a carbocycle or a heterocycle having a reactive center susceptible to nucleophilic attack by the nucleophile, in the presence of a chiral non-racemic catalyst to produce a product mixture comprising a stereomerically enriched product wherein the product mixture further comprises a catalyst residue, at least a portion of the catalyst residue is in a first oxidation state, and the catalyst residue in the first oxidation state is active in catalyzing degradation of the stereoisomerically enriched product, and (B) chemically or electochemically changing the oxidation state of the catalyst residue from the first oxidation state to a second oxidation state, wherein catalyst residue in the second oxidation state is less active in catalyzing degradation of the stereoisomerically enriched product than is catalyst residue in the first oxidation state. The method reduces erosion of the chiral purity of the stereoisomerically enriched product and reduces the chemical transformation to side products of the stereoisomerically enriched product and co-product(s). The deactivated catalyst is recoverable and recyclable.