专利号:US-7087743-B2 优先权日:2000-02-11 标 题 :Oligonucleotides and use of oligonucleotides modulating the expression of enzymes involved in the synthesis of melanic pigments, as depigmentation agents 发明人:KURFURST ROBIN; JOLY REGINE 权利人:LVMH RECH 摘要:The present invention relates to novel oligonucleotide sequences and also to derivatives thereof. n These novel oligonucleotide sequences are capable of hybridizing specifically with the gene or with a product of the gene encoding tyrosinase, or with the gene or a product of the gene encoding tyrosinase-related-protein 1 (TRP-1). n The present invention also relates to the use of these novel oligonucleotide sequences as a depigmenting or bleaching agent in a cosmetic composition or in a dermatological composition.
专利号:US-11529370-B2 优先权日:2017-11-24 标 题 :Use of composition comprising stem cell-derived exosome as effective ingredient in strengthening skin barrier and improving skin barrier function 发明人:YI YONG WEON; CHO BYONG SEUNG 权利人:EXOCOBIO INC 摘要:A composition for strengthening skin barrier or improving skin barrier function is able to improve objective indicators related to the protection of skin barrier, the strengthening of skin barrier, and/or the improvement of skin barrier function. The composition exhibits the effects of increasing the amount of ceramides, dihydroceramides and sphingoid bases, increasing the activities of enzymes that are involved in the synthesis thereof, and decreasing the activities of enzymes that are involved in the degradation thereof. In addition, the composition is able to restore skin barrier function by reducing TSLP, IL-4, and IL-13 which are closely associated with skin barrier damage, and thus interrupting a vicious circle in which the lipids and proteins contributing to skin barrier decrease.
专利号:US-2012237623-A1 优先权日:2009-12-04 标题 :Topical Compositions Containing Derris Scandens Benth and a Method of Treating Skin 发明人:PTCHELINTSEV DMITRI S; LUO XIAOCHUN 权利人:PTCHELINTSEV DMITRI S; LUO XIAOCHUN; AVON PROD INC 摘要:Topical compositions and methods of use to treat symptoms of reduced skin elasticity are provided comprising extracts of a. Derris scandens Benth. plant. These compositions are effective in stimulating LOXL-1, activity, inhibiting calcineurin activity, and stimulating glycosaminoglycan synthesis in skin cells and can thus reduce age-related skin damage and improve appearance of fine lines, wrinkles, skin sagging and other symptoms of skin aging and/or skin damage.
专利号:US-8575106-B2 优先权日:2009-08-31 标题:Cosmetic uses of modified stressed yeast extracts and related compositions 发明人:SANTHANAM UMA; KYROU CHRISTOS D; MAZICH DESIREE; HONG QI; SHAHEEN HUSSAM H 权利人:SANTHANAM UMA; KYROU CHRISTOS D; MAZICH DESIREE; HONG QI; SHAHEEN HUSSAM H; AVON PROD INC 摘要:Cosmetic compositions comprising a metal-complexed peptide fraction of stressed yeast extracts and/or a calcium influx inhibitor are disclosed, as well as methods of using such compositions to impart exfoliating, anti-aging, anti-lipid, anti-inflammatory, and/or lightening benefits to the skin; and/or lightening benefits to the hair. These compositions are believed to have modulatory activity against at least one biochemical pathway implicated in skin aging, inflammation, lipid synthesis, and melanin production.
专利号:CN-101067135-A 优先权日:2000-02-11 标题 :Novel oligonucleotides and use of oligonucleotides modulating the expression of enzymes involved in the synthesis of melanic pigments, as depigmentation agents
专利号:JP-2008043334-A 优先权日:2000-02-11 标 题:New oligonucleotide and use of oligonucleotide modulating expression of enzyme involved in synthesis of melanic pigment, as decolorant
摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118 摘要:International Journal of Toxicology 25(Suppl. 2) :1-89,2006 摘要:International Journal of Toxicology 34(Suppl.3):61-73, 2015 摘要:Journal of the American College of Toxicology 1(4):81-90, 1982