欧盟法规
ECHA物质C&L通报REACH预注册1-氨基-2-甲基胍置于盐酸,Sodium Nitrite体系中,化学反应生成 1-甲基-5-氨基四氮唑
参考文献:Preparation And Isomerization Of 5-Alkylaminotetrazoles
标题:Preparation And Isomerization Of 5-Alkylaminotetrazoles
摘要:
DOI:10.1021/jo50013A002
专利信息
专利号:WO-2020240266-A1
优先权日:2019-05-31
标题:New endoperoxide compounds, process for obtaining them and uses thereof for control of perkinsiosis in bivalves
发明人:CRISTIANO MARIA; CABRAL LÃ?LIA; LEITE RICARDO; LEAL JOSÉ
权利人:CCMAR CENTRO DE CIENCIAS DO MAR UNIV DO ALGARVE; INST GULBENKIAN DE CIENCIA
摘要:The present invention relates to new endoperoxide compounds and compositions, and to a process for producing them for prophylaxis and control of perkinsiosis in bivalves. Endoperoxide compounds with biological activity against Perkinsus olseni include 13 trioxolanes and 9 tetraoxanes. Protozoan parasites of the genus Perkinsus are known to infect several species of marine molluscs worldwide, like oysters, abalones, clams, scallops, pearl oysters, cockles or mussels. The present invention also describes the synthesis of these compounds, in particular of new endoperoxide compounds of the tetraoxane family. Compositions comprising endoperoxide compounds are useful for prophylaxis and control of perkinsiosis in bivalves. Therefore, the present invention also relates to a method of controlling perkinsiosis in bivalves. The present invention is in the domain of aquaculture, medicine, pharmaceuticals and biochemistry.
专利号:US-11512097-B2
优先权日:2019-11-25
标题 :Heterocyclic compounds as Delta-5 desaturase inhibitors and methods of use
发明人:ALLEN JENNIFER R; BELTRANI MICHELA; BOURBEAU MATTHEW P; DAMYANOVA TEODORA P; LINGARD IAIN; MINATTI ANA E; VINCETTI PAOLO
权利人:AMGEN INC
摘要:The present disclosure provides compounds useful for the inhibition of Delta-5 Desaturase (“D5Dâ€?). The compounds have a general Formula I n nwherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a metabolic or cardiovascular disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.
专利号:WO-2023213264-A1
优先权日:2022-05-05
标 题 :Synthesis of amide compound and use thereof
发明人:WANG ZHAOYIN; ZHANG JIAN; CAO JINRUI
权利人:SHANGHAI INST ORGANIC CHEMISTRY CAS
摘要:The present invention relates to a novel oleanamide derivative for activating a KEAP/NRF2/ARE signaling pathway. The compound of the present invention is represented by general formula (I), wherein L, R 3 , R 4 , Z, and n are set forth in the description specification and the claims. Also disclosed are a method for preparing the compound represented by general formula I and an activity test result thereof for activating the KEAP/NRF2/ARE signaling pathway. The compound represented by general formula (I) of the present invention can be used for treating and preventing multiple sclerosis (MS), Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), Friedreich's ataxia (FRDA), spinal muscular atrophy (SMA), neuromyelitis optica (NMO), spinocerebellar ataxia (SCA), and other neurodegenerative diseases, and can also be used for treating cerebral apoplexy, autoimmune diseases, diabetes, kidney diseases, and other chronic diseases.
专利号:CN-117050134-A
优先权日:2022-05-05
标 题 :Synthesis of amide compounds and their uses
专利号:CN-116856063-A
优先权日:2023-07-06
标题:A kind of crystal material and its synthesis method, energetic material and application
专利号:CN-113896748-A
优先权日:2021-11-05
标题 :A kind of dinuclear ferrocene-based energetic compound and its synthesis method and application