CAS: 35141-30-1; N1-(2-Aminoethyl)-N2-(3-(Trimethoxysilyl)Propyl)Ethane-1,2-Diamine

该化合物是一种双功能有机硅烷联结剂,具有反应性三甲基环氧基环乙胺和二乙基苯三胺组,其主要优势在于它能够通过形成强大的共价联系,加强有机聚合物和无机亚基体(如玻璃,金属或矿物)之间的粘合.三甲基环乙基环乙胺的氢解合剂与硅醇的结合,能够与氢氧基表面结合,而矿能促进与树脂,天花和其他有机基体的相互作用.这种化合物在涂层,粘合剂和复合材料方面特别有用,因为需要改进机械特性和耐久性.它的双重再活性也使其在地表改造和腐蚀抑制剂应用中具有价值.

结构式图片

相似化合物

1760-24-3 51895-58-0 82985-35-1

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

3-azapentane-1,5-diamine 3-Chloropropyltrimethoxysilan

合成工艺路线路线简述

    二乙烯三胺,3-氯丙基三甲氧基硅烷置于sodium Methylate体系中,用 甲醇 作为反应溶剂,化学反应 11.0H,反应生成 二乙烯三胺基丙基三甲氧基硅烷
    参考文献:Method For Manufacturing Amino Group-Containing Organosilicon Compound
    标题:Method For Manufacturing Amino Group-Containing Organosilicon Compound
    摘要:一种制造含有氨基基团的有机硅化合物的方法,该化合物具有以下式子(1):其中,每个r1分别表示具有1到10个碳原子的烷基基团等;每个r2和r3表示以下式子(4)的官能团等;m表示1到3的整数,N表示1到12的整数;其中,星号*表示与相邻原子的键;p表示1到12的整数,Q表示1到10的整数.该方法包括:(a)将以下式子(2)的胺化合物与以下式子(3)的含卤基有机硅化合物反应:其中,X表示氯原子等,R1和n的含义与上述相同;(b)通过液-液分离去除步骤(a)中产生的胺盐酸盐;以及(c)使用相当于有机层中含有的卤离子的0.1到0.95摩尔当量的碱中和步骤(b)中获得的有机层.

    海关参考信息

    专利信息


    专利号:WO-2025044766-A1
    优先权日:2023-08-31
    标题:Use of silicon dioxide microspheres in synthesis of ultra-long oligonucleotide and method for synthesizing ultra-long oligonucleotide
    发明人:SHI YONGYONG; ZHANG MANCANG; WANG LIBING; GAO PANPAN; FANG JUN
    权利人:UNIV SHANGHAI JIAOTONG; SHANGHAI DYNEGENE TECH CO LTD
    摘要:The present invention relates to the technical field of oligonucleotide synthesis. Disclosed are the use of silicon dioxide microspheres in the synthesis of an ultra-long oligonucleotide and a method for synthesizing an ultra-long oligonucleotide, wherein the silicon dioxide microspheres have a specific surface area of less than 1 m2/g, and preferably, the silicon dioxide microspheres have modification groups on the surface. The method for synthesizing an ultra-long oligonucleotide comprises: performing a coupling reaction on a nucleoside phosphoramidite synthesis unit using the silicon dioxide microspheres having modification groups on the surface as carriers under coupling reaction conditions. The prepared carriers can be used to prepare an ultra-long oligonucleotide.

    专利号:US-2013165350-A1
    优先权日:2011-12-22
    标 题:Surface linkers for array synthesis
    发明人:KUIMELIS ROBERT; MCGALL GLENN; PAO DEXTER; CHEN ZIHUI; AXELROD TREVOR
    权利人:KUIMELIS ROBERT; MCGALL GLENN; PAO DEXTER; CHEN ZIHUI; AXELROD TREVOR; AFFYMETRIX INC
    摘要:The present invention provide several methods of derivatizing a surface of a support with one or more linkers thus providing a suitable platform for synthesis of a polymer array, particular a nucleic acid array. Some methods derivatize a surface with a self-assembled monolayer (SAM) of a linker. The SAM confers advantages of hydrolytic stability, broad compatibility with synthesis and detection chemistries, and reduced emergence of latent functional groups during polymer array synthesis. Substrates can also be derivatized with multi-layers of SAMs providing greater hydrolytic stability. Substrates can also be derivatized by synthesizing a linker in situ on the substrate by atom transfer radical polymerization of functional and functional monomers. Appropriate selection of monomers reduces emergence of latent functional groups in subsequent array synthesis.

    专利号:US-11738328-B2
    优先权日:2021-04-30
    标题:Single-step synthesis of chemisorption fiber sorbents (CHEFS) for the capture of CO2 and removal of water contaminants
    发明人:GRAY MCMAHAN L; SHI FAN; YI SHOULIANG; WILFONG WALTER CHRIS; WANG QIUMING
    权利人:US ENERGY
    摘要:One or more embodiments relates to method for generating CHEFS having the steps of generating the CHEFS from a dope. One or more embodiments relates to a method for generating CHEFS having amine functional groups having the steps of generating a dope containing a BIAS with amine groups, at least one polymer, and at least one solvent; and forming CHEFS from the dope, wherein the generated CHEFS have no more than 30% amine loss compared to the BIAS.

    专利号:US-2015140595-A1
    优先权日:2012-05-22
    标题 :Formulations for the synthesis of paramagnetic particles and methods that utilize the particles for biochemical applications
    发明人:UTERMOHLEN JOSEPH GERARD
    权利人:UTERMOHLEN JOSEPH GERARD
    摘要:A set of paramagnetic particles synthesized by co-precipitation methods wherein an alkaline hydroxide solution is mixed with a metal salt solution. The alkaline hydroxide features ammonium hydroxide, potassium hydroxide, sodium hydroxide, or mixtures thereof. The metal salt solution features at least one ferrous salt and at least one tetravalent metal salt selected from Group 4 elements of the Periodic Table. The concentration of the ferrous salt is equal to or greater than the concentration of the tetravalent metal salt. The paramagnetic particles may be used for bioprocessing via magnetic fields. Bioprocessing, for example, may include purifying, concentrating, or detecting biomolecules of interest (e.g., nucleic acids, carbohydrates, peptides, proteins, other organic molecules, cells, organelles, microorganisms, viruses, etc.), or other magnetic field-based processes common to applications in separation science, diagnostics, molecular biology, protein chemistry, and clinical practice.

    专利号:US-2013211542-A1
    优先权日:2012-02-08
    标题:Synthesis of nanotopographic biomimetic membranes for tissue culture, engineering and prosthetics applications
    发明人:MCKEE CLAYTON; MURPHY CHRISTOPHER J; RUSSELL PAUL; GARLAND SHAUN P
    权利人:UNIV CALIFORNIA; UNIV CALIFORNIA
    摘要:The present invention provide methods for preparing nanostructured membranes. The methods include: providing a substrate with a charged silanized surface; forming a multilayered membrane containing at least two polyelectrolytes; inducing polyelectrolyte phase separation; crosslinking the multilayered membrane; and covalently linking the multilayered membrane to the silanized surface. Methods for fabricating membrane replicas are also disclosed, as well as devices such as cell- and tissue-culture substrates that contain the membranes and membrane replicas. Resulting materials exhibit topographic features and compliance of the extracellular matrix in vivo.

    专利号:US-12215039-B2
    优先权日:2018-11-20
    标题:Synthesis, capping, and dispersion of TiO2 nanocrystals
    发明人:REPAC JASON ALLEN; WILLIAMS SERPIL GONEN; MONICKAM SELINA THOMAS; WIACEK ROBERT J
    权利人:PIXELLIGENT TECH LLC; PT SPE SUBCO LLC
    摘要:The preparation of monodispersed TiO 2 nanocrystals with nanocrystal size between 1-30 nm is described herein. These TiO 2 nanocrystals are used to prepare dispersions into solvents, formulation into monomers, oligomers, and polymers, and nanocomposites from the resulting formulations. Dispersions of nanocrystals can be formed in various solvents at high loading, high transmittance, and low viscosity. Formulations incorporating these nanocrystals and a matrix material are highly stable, where the resulting nanocomposites have high refractive index and are optically transparent in the visible wavelengths, with very little or no scattering.
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    主要参考文献

    [参考文献]: Aundrea R Piper-Feldkamp, Et Al. Mixtures Of Supported And Hybrid Lipid Membranes On Heterogeneously Modified Silica Nanoparticles. J Phys Chem B. 2013 Feb 21;117(7):2113-22.
    [参考文献]: Takahito Nakagawa, Et Al. Fabrication Of Amino Silane-Coated Microchip For Dna Extraction From Whole Blood. J Biotechnol. 2005 Mar 16;116(2):105-11.
    [参考文献]: Y Fang, Et Al. Surface-Directed Dna Condensation In The Absence Of Soluble Multivalent Cations. Nucleic Acids Res. 1998 Jan 15;26(2):588-93.

    合成参考文献


    参考文献:10.1016/j.biomaterials.2004.01.020|10.1016/s0142-9612(04)00061-4
    摘要:Das M, Molnar P, Gregory C, Riedel L, Jamshidi A, Hickman JJ. Long-term culture of embryonic rat cardiomyocytes on an organosilane surface in a serum-free medium. Biomaterials. 2004 Nov;25(25):5643–7. doi: 10.1016/j.biomaterials.2004.01.020.
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