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专利信息

专利号:US-2003229922-A1
优先权日:1998-10-13
标题 :Materials and methods for the modification of plant cell wall polysaccharides
发明人：BLOKSBERG LEONARD N
权利人:GENESIS RES & DEV CORP LTD; RUBICON FORESTS HOLDINGS LTD
摘要:Novel isolated polynucleotides and polypeptides associated with the synthesis of plant cell wall polysaccharides are provided, together with genetic constructs comprising such sequences. Methods for using such constructs for the modulation of polysaccharide content in plants are also disclosed, together with transgenic plants comprising such constructs.

专利号:US-2023219881-A1
优先权日:2022-01-11
标题 :Synthesis of Spermidine, Spermine, and Free Bases Thereof
发明人：TITLOW MATTHEW; GU XINGLONG
权利人:COMPOUND SOLUTIONS INC; SHAOXING KING YEAR BIOCHEMICAL CO LTD
摘要:A simplified synthetic process for production of spermine and spermidine are presented that can provide spermine and spermidine in free base or salt form. Advantageously, the synthetic procedure is safe, simple, and environmentally friendly, while at the same time also being cost-effective.

专利号:EP-0320272-B1
优先权日:1987-12-09
标 题 :DNA encoding ACV synthetase
发明人：BURNHAM MARTIN KARL RUSSELL; EARL ALISON JANE; BULL JOHN HENRY UNIVERSITY OF; SMITH DAVID JOHN UNIVERSITY OF; TURNER GEOFFREY UNIVERSITY OF
权利人:BEECHAM GROUP PLC
摘要:DNA encoding the gene for the synthetase enzyme capable of generating delta (L- alpha -aminoadipyl)-L- cysteinyl-D-valine (ACV) from its constituent amino acids was obtained from several penicillin and cephalosporin producing organisms, e.g. Penicillium chrysogenum and a Flavobacterium species. The DNA was used to prepare recombinant vectors comprising the ACV synthetase gene and hosts transformed with such vectors. The ACV synthetase gene can form part of a gene cluster comprising other genes involved in beta -lactam biosynthesis and the production of penicillin by expression of the entire biosynthetic gene cluster for the synthesis of penicillin from primary amino acids is described. Suitable hosts in which expression can take place include heterologous hosts which are naturally non-producers of penicillin.

专利号:US-6210931-B1
优先权日:1998-11-30
标题 :Ribozyme-mediated synthesis of circular RNA
发明人：FELDSTEIN PAUL A; OWENS ROBERT A; LEVY LAURENE; RANDLES JOHN W
权利人:US AGRICULTURE
摘要:Circular RNAs may be synthesized by inserting DNA fragments into a plasmid containing sequences having the capability of spontaneous cleavage and self-circularization. Insertion of the DNA fragments allows RNAs of predetermined size to be constructed. In addition, a two-dimensional polyacrylamide gel electrophoresis system having a second dimension more highly cross-linked than the first dimension permits the separation and analysis as well as the precise sizing of both linear and circular RNAs produced by the synthetic method.

专利号:WO-9503432-A1
优先权日:1993-07-23
标题:Linked linear amplification of nucleic acids
发明人：WALLACE ROBERT BRUCE
权利人:BIO RAD LABORATORIES
摘要:The extensive synthesis ('amplification') of a nucleic acid sequence of interest is attained through a linked series of multi-cycle primer extension reactions (LLA). The primers used in each of the primer extension reactions of the process contain non-replicable elements that halt nucleic acid synthesis and thereby prevent the synthesized molecules from serving as templates in subsequent cycles. Synthesized molecules accumulate during primer extension in a mathematically linear fashion, thereby rendering the process relatively insensitive to contaminating nucleic acids. Multiple primer sets are employed, thereby ensuring the accumulation of a large number of copies of the nucleic acid sequence of interest. The invention also provides for the detection of an amplified nucleic acid sequence of interest, as well as reagent kits for carrying out the reaction.

专利号:US-2004091923-A1
优先权日:1993-07-23
标题:Linked linear amplification of nucleic acids
发明人：REYES ANTONIO AREVALO; WALLACE ROBERT BRUCE; UGOZZOLI LUIS A
权利人:BIO RAD LABORATORIES
摘要:The generation and extensive synthesis (“amplificationâ€?) of a cDNA sequence of interest is attained through a linked series of multi-cycle primer extension reactions (RT-LLA). The primers used in each of the primer extension reactions of the process contain non-replicable and, in some cases non-replicable and cleavable, elements that halt nucleic acid synthesis and thereby prevent the synthesized molecules from serving as templates in subsequent cycles. Synthesized molecules accumulate during primer extension in a mathematically linear fashion, thereby rendering the process relatively insensitive to contaminating nucleic acids. Multiple primer sets are employed, and simultaneously included in the reaction mixture, thereby ensuring the accumulation of a large number of copies of the cDNA sequence of interest.