CAS: 27532-96-3; H-Gly-Otbu.Hcl

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邻苯二甲酰亚胺基-甘氨酸叔丁酯置于一水合肼体系中,用 二氯甲烷,1,4-二氧六环 用作溶剂,化学反应生成甘氨酸叔丁酯盐酸盐
参考文献:Wo2022/219485
标题:Wo2022/219485

专利信息

专利号:US-2022298204-A1
优先权日:2019-07-05
标题 :Synthesis of a-amanitin and its derivatives
发明人：SIEGERT MARY-ANN; KNITTEL CAROLINE HERTA; SÃœSSMUTH RODERICH
权利人:PURE BIOORGANICS SIA
摘要:The present invention relates to the chemical synthesis of α-amanitin and its derivatives. The present invention also relates to intermediate products of the α-amanitin synthesis.

专利号:EP-3792250-A1
优先权日:2019-09-13
标题:Synthesis of alpha-amanitin and its derivatives
发明人：SIEGERT MARY-ANN; KNITTEL CAROLINE HERTA; SÃœSSMUTH RODERICH
权利人:PURE BIOORGANICS SIA
摘要:The present invention relates to the chemical synthesis of α-amanitin and its derivatives. The present invention also relates to intermediate products of the α-amanitin synthesis.

专利号:US-5965719-A
优先权日:1996-11-15
标 题:Combinatorial synthesis of carbohydrate libraries
发明人：HINDSGAUL OLE
权利人:SUNSORB BIOTECH INC
摘要:Disclosed are methods for synthesizing very large collections of diverse thiosaccharide derivatives optionally attached to a solid support. Also disclosed are libraries of diverse thiosaccharide derivatives.

专利号:EP-1567195-B1
优先权日:2002-11-26
标题 :Dendrimer conjugates for selective solubilisation of protein aggregates
发明人：HEEGAARD PETER; BOAS ULRIK
权利人:UPFRONT CHROMATOGRAPHY AS
摘要:Dendrimer conjugates are presented, which are formed between a dendrimer and a protein solubilising substance. Such dendrimer conjugates ar effective in the treatment of protein aggregate-related diseases (e.g. prion-related diseases). The protein solubilising substance and the dendrimer together show a protein aggregate solubilising effect higher than a physical mixture of the dendrimer and the protein solubilising substance (i.e. a synergistic effect). Such dendrimer conjugates are useful in the treatment or prevention of protein aggregate-relates diseases, in disinfection/decontamination processes and in classifying or identifying protein aggregates. The synthesis of such dendrimer conjugates from readily-available starting materials is described.

专利号:US-8324417-B2
优先权日:2009-08-19
标题:Process for the preparation of (S)-2-amino-5-cyclopropyl-4,4-difluoropentanoic acid and alkyl esters and acid salts thereof
发明人：HART BARRY; DENER JEFF; GREEN MICHAEL; STANDEN MICHAEL; KOCIAN OLDRICH
权利人:HART BARRY; DENER JEFF; GREEN MICHAEL; STANDEN MICHAEL; KOCIAN OLDRICH; VIROBAY INC
摘要:The present invention relates to a process for the preparation of alkyl esters of (S)-2-amino-5-cyclopropyl-4,4-difluoropentanoic acid, which are intermediates useful in the synthesis of (S)—N-(1-cyanocyclopropyl)-5-cyclopropyl-4,4-difluoro-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)pentanamide and related compounds, which are compounds that are cysteine protease inhibitors.

专利号:US-2009215986-A1
优先权日:2006-03-08
标题:Solution Synthesis of Peptide Cell Growth Stimulators
发明人：EPSTEIN DAVID; KRUSZYNSKI MARIAN F; MARSH CHRISTOPHER; SCHMIDT ALBERT
权利人:EPSTEIN DAVID; KRUSZYNSKI MARIAN F; MARSH CHRISTOPHER; SCHMIDT ALBERT
摘要:A solution phase synthetic method for preparing basic tripeptides of the formula Gly-Xaa-Gly-X which have in various biological properties such as stimulating protein production when used as additives in a bioreactor. The basic tripeptides of the invention may be produced on gram or kilogram scale.