CAS: 271-58-9; Benzo[c]Isoxazole

相似化合物

139557-44-1 4596-92-3 566194-03-4

上下游产品

2-azidobenzaldehyde diethyl ether 2-Nitrobenzyl alcohol 1-methyl-2-nitrobenzene t.9at)-9,9a-dihydro-3aH-4r,9c-epoxido-pyrrolo[3,4-b]quinoline-1,3-dione(+/-)-2-phenyl-(3at.9at)-9,9a-dihydro-3aH-4r,9c-epoxido-pyrrolo[3,4-b]quinoline-1,3-dione N-(2-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)phenyl)benzenesulfonamide isatoic anhydride 2-methyl-4-oxo-3,1-benzoxazine

2-Nitro-Benzaldehyd置于hcl (G)体系中,用 溶剂黄146 用作溶剂,以16.2 G (66%)的收率获得苯甲醯亞胺酸
参考文献:Inhibitors Of Protein Tyrosine Kinases
标题:Inhibitors Of Protein Tyrosine Kinases
摘要:披露了小分子,非肽类蛋白酪氨酸激酶抑制剂,以及它们的使用方法.本发明的抑制剂基于1,4-苯并二氮杂-2-酮核心结构.提供了抑制特定蛋白酪氨酸激酶的方法,例如pp60.Sup.C-Src.进一步提供了在这些抑制剂的使用情况下,例如在治疗哺乳动物,包括人类的某些疾病时,抑制蛋白酪氨酸激酶的方法.

专利信息

专利号:US-8569560-B2
优先权日:2006-10-13
标题 :Synthesis of terminal alkenes from internal alkenes via olefin metathesis
发明人：SCHRODI YANN; PEDERSON RICHARD L; KAIDO HIROKI; TUPY MICHAEL J
权利人:ELEVANCE RENEWABLE SCIENCES
摘要:This disclosure relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by an olefin metathesis catalyst. According to one aspect, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting, in the presence of a ruthenium alkylidene metathesis catalyst, an olefinic substrate comprised of at least one internal olefin with a cross metathesis partner comprised of an alpha olefinic reactant, under reaction conditions effective to allow cross-metathesis to occur, wherein the reaction conditions include a reaction temperature of at least 35° C. The methods, compositions, reactions and reaction systems herein disclosed have utility in the fields of catalysis, organic synthesis, and industrial chemistry.

专利号:WO-0027627-A1
优先权日:1998-11-12
标题 :Aryloxime linkers in the solid-phase synthesis of 3-aminobenzisoxazoles
发明人：WILEY MICHAEL ROBERT; LEPORE SALVATORE DONATO
权利人:LILLY CO ELI; WILEY MICHAEL ROBERT; LEPORE SALVATORE DONATO
摘要:In its first aspect, the invention is directed to a solid support mediated method for the synthesis of diverse polycyclic heterocycles according to general formula (V). A second aspect of the invention is directed to a solid support bound intermediate compound that optionally can be derivatized before a cyclization and displacement procedure provides a product. The intermediate is preferably stable to a wide range of chemical conditions thus allowing, if desired, for the chemical derivatization of the intermediate. A third aspect of the invention is directed to a library of polycyclic heterocycle compounds where said library contains a plurality of diverse library compounds of general formula (V). A fourth aspect of the invention is directed to a method for the synthesis of a library of diverse polycyclic heterocycles by the general method described. A fifth aspect of the invention is directed to an assay kit for the identification of lead compounds of the library described therein.

专利号:US-9255117-B2
优先权日:2006-07-13
标题 :Synthesis of terminal alkenes from internal alkenes and ethylene via olefin metathesis
发明人：SCHRODI YANN
权利人:MATERIA INC
摘要:This invention relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by a selected olefin metathesis catalyst. In one embodiment of the invention, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting an olefinic substrate comprised of at least one internal olefin with ethylene, in the presence of a metathesis catalyst, wherein the catalyst is present in an amount that is less than about 1000 ppm relative to the olefinic substrate, and wherein the metathesis catalyst has the structure of formula (II) n nwherein the various substituents are as defined herein. The invention has utility, for example, in the fields of catalysis, organic synthesis, and industrial chemistry.

专利号:WO-2024062080-A1
优先权日:2022-09-21
标题:Improved synthesis of psilocybin derivatives
发明人：HAMMES CHRISTIAN; STÖCKLI STEFAN
权利人:CARBOGEN AMCIS AG; AAMANYA AG
摘要:The present invention relates to an improved synthesis of psilocybin and alkyl- derivatives of psilocybin such as ethocybin (4-phosphoryloxy-N,N-diethyltryptamine, also known as phosphoryloxy-DET, PO-DET or CEY-39) and furthermore, relates to intermediates useful in the synthesis of these compounds.

专利号:US-6946533-B2
优先权日:2002-08-01
标 题 :Synthesis of macrocyclic polymers by ring insertion polymerization of cyclic olefin monomers
发明人：GRUBBS ROBERT; BIELAWSKI CHRIS; BENITEZ DIEGO
权利人:CALIFORNIA INST OF TECHN
摘要:A method for synthesizing cyclic polymers using transition metal alkylidene complexes as reaction catalysts is provided, wherein the complexes contain a cyclic group. Polymerization is carried out on the catalyst, using cyclic olefin monomers that undergo ring insertion polymerization, and no linear intermediates are generated. Following completion of polymerization, the cyclic polymer detaches from the complex via an intramolecular chain transfer reaction and the catalytic complex is regenerated. The invention also provides novel transition metal alkylidene complexes useful as catalysts in the aforementioned process, as well as novel cyclic hydrocarbons.

专利号:WO-2023031333-A1
优先权日:2021-09-01
标 题:Polymeric soluble support, process for the synthesis thereof and uses thereof
发明人：RANDRIANJATOVO-GBALOU IRINA; SAID AHMED; KEBE SEYDINA IBRAHIMA
权利人:SYNHELIX
摘要:The present invention relates to a process for the synthesis of an organic molecule, comprising the use of a polymeric soluble support. The invention further relates to the polymeric soluble support, and to a process for the synthesis thereof.