专利号:US-12281398-B2 优先权日:2022-02-07 标题:Microfluidic process for the general electrochemical synthesis of geminal dipseudohalide or halide-pseudohalide compounds 发明人:SCHROER THORSTEN G; LECROY GREGORY E; AGUILA MIGUEL; RODRIGUEZ MAYRA P; DOWNARD TYLER J; MACLEOD BRIANNA L 权利人:US GOV AIR FORCE; US AIR FORCE 摘要:A process for the microfluidic electrochemical synthesis of geminal dipseudohalide or halide-pseudohalide compounds comprising the steps ofpumping a solution comprising a compound of Formula Iinto a microfluidic electrochemical reactor in the presence of a base, one of a halide or pseudohalide salt (MY), and a mediator;applying an electrical current through the microfluidic electrochemical reactor; andperforming oxidative addition to create a geminal dipseudohalide or halide-pseudohalide compound of the general Formula II
专利号:US-2024218528-A1 优先权日:2022-02-07 标题 :Microfluidic Process for the General Electrochemical Synthesis of Geminal Dipseudohalide or Halide-Pseudohalide Compounds
专利号:US-7713401-B2 优先权日:2007-08-08 标 题 :Methods for performing electrochemical nitration reactions 发明人:LISTER TEDD EDWARD; FOX ROBERT VINCENT 权利人:BATTELLE ENERGY ALLIANCE LLC 摘要:A method for the electrochemical synthesis of dinitro compounds is disclosed. The method comprises using an anode to oxidize an inactive chemical mediator, such as a ferrocyanide (Fe(CN) 6 −4 ) ion, to an active chemical mediator or oxidizing agent, such as a ferricyanide (Fe(CN) 6 −3 ) ion, in the presence of a differential voltage. The oxidizing agent reacts with a nitro compound and a nitrite ion to form a geminal dinitro compound. The anode may continuously oxidize ferrocyanide to regenerate active ferricyanide, thus keeping sufficient amounts of ferricyanide available for reaction.
专利号:US-2023250540-A1 优先权日:2022-02-07 标题 :Microfluidic Process for the General Electrochemical Synthesis of Geminal Dipseudohalide or Halide-Pseudohalide Compounds
专利号:US-11926911-B2 优先权日:2022-02-07 标题:Microfluidic process for the general electrochemical synthesis of geminal dipseudohalide or halide-pseudohalide compounds
[参考文献]: C C Conaway, Et Al. Evaluation Of Secondary Nitroalkanes, Their Nitronates, Primary Nitroalkanes, Nitrocarbinols, And Other Aliphatic Nitro Compounds In The Ames Salmonella Assay. Mutat Res. 1991 Nov;261(3):197-207.
合成参考文献
摘要:MacMillan, D. W. C.; Watson, A. J. B., Science of Synthesis: Asymmetric Organocatalysis, (2012) 1, 345.