CAS: 17715-69-4; 1-Bromo-2,4-Dimethoxybenzene

上下游产品

CAS号151-10-0 间苯二甲醚 | CAS号6626-15-9 4-溴间苯二酚 | CAS号74-88-4 碘甲烷 | CAS号91-52-1 2,4-二甲氧基苯甲酸 | CAS号506-68-3 溴化氰 | CAS号89-86-1 2,4-二羟基苯甲酸 | CAS号7355-22-8 5-溴-2,4-二羟基苯酸 | CAS号77-78-1 硫酸二甲酯 | CAS号348-57-2 2,4-二氟溴苯 | CAS号865-33-8 甲醇钾 | CAS号578-16-5 2,2,2-三氟-2',4'-... | CAS号4107-65-7 2,4-二甲氧基苯甲腈 | CAS号91-52-1 2,4-二甲氧基苯甲酸 | CAS号151-10-0 间苯二甲醚 | CAS号3555-85-9 2 2' 4 4'-TETRA... | CAS号76832-37-6 三(2,4-二甲氧苯基)甲醇 | CAS号38064-90-3 2,4-二甲氧基甲苯 | CAS号613-45-6 2,4-二甲氧基苯甲醛 | CAS号24890-52-6 2,4-dimethoxy-1... | CAS号78046-28-3 5-氯-2,4-二甲氧基-苯磺酰氯

间苯二甲醚置于sodium Orthovanadate,Vanadium Dependent Haloperoxidase From Acaryochloris Marina Mbic 11017,2,6-蒽二酚,Potassium Bromide体系中,用 乙腈 用作溶剂,化学反应 16.0H,以99%的收率获得2,4-二甲氧基溴苯
参考文献:用于光生物催化卤代反应的原子经济电子给体
标题:用于光生物催化卤代反应的原子经济电子给体
摘要:体外辅因子的供应和再生一直是生物催化过程的主要障碍,特别是在大规模生产中.过氧化物酶通常会因其氧化辅助因子而失活.将光催化和生物催化相结合可为该问题提供创新的解决方案,但由于需要牺牲电子供体,因此缺乏原子经济性.在此,我们表明,与光催化结合使用时,具有氧化还原活性的缓冲液甚至是单独的水都可以用作有效的生物相容性电子源.机理研究揭示了对该方法的可能性和局限性的初步见解,并允许根据生物催化转化的具体需要调整反应条件.这种光生物催化反应装置的适用性的概念证明是通过酶促卤化作用给出的.
Doi:10.1002/cctc.201800886

专利信息

专利号:US-4985567-A
优先权日:1988-03-07
标题:Chiral phosphinopyrrolidine compounds and their use for asymmetric synthesis of optically active compounds
发明人：ACHIWA KAZUO; TAKEDA HIDEO
权利人:KAZUO ACHIWA; FUJI YAKUHIN KOGYO KK
摘要:New chiral phosphinopyrrolidine compounds of the general formula: ##STR1## wherein R 1 is hydrogen or --COA 1 , --COOA 2 , --CONHA 3 , --SO 2 A 4 or --PO(A 5 ) 2 , A 1 , A 2 , A 3 , A 4 and A 5 each represents independently alkyl or aryl, R 2 is phenyl, di(lower-alkyl)aminophenyl, lower-alkoxyphenyl or 3,5-dimethyl-4-methoxyphenyl, and R 3 is phenyl, lower-alkylphenyl, di(lower-alkyl)aminophenyl, lower-alkoxyphenyl or 3,5-dimethyl-4-methoxyphenyl, with the proviso that R 2 and R 3 may not simultaneously by phenyl, p-di(lower-alkyl)-aminophenyl or p-lower-alkoxyphenyl, as well as the use of these compounds as ligand for a metal complex catalyst for asymmetric synthesis of optically active compounds. The new chiral phosphinopyrrolidine compounds are useful ligands which attain both of high optical yield and high reaction efficiency in catalytic asymmetric reduction.

专利号:US-7884125-B2
优先权日:2008-04-30
标 题:Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues
发明人：STEVENS CHRISTIAN; HEUGEBAERT THOMAS
权利人:UNIV GENT
摘要:The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.

专利号:US-7339075-B2
优先权日:2005-08-31
标题 :Ligand synthesis
发明人：ALLEN NATHAN TAIT; GOODALL BRIAN LESLIE; KIRK THOMAS CLEVELAND; MCINTOSH III LESTER HOWARD
权利人:ROHM & HAAS
摘要:Ligand synthesis methods for the preparation of ligands having the formula n nwherein Q is selected from phosphorus, arsenic and antimony; wherein X 1 , X 2 and X 3 are carbon anions; and, wherein R 15 is selected from —SO 3 , —SO 2 N(R 18 ), —CO 2 , —PO 3 , —AsO 3 , —SiO 2 , —C(CF 3 ) 2 O; where R 18 is selected from a hydrogen, a halogen, a hydrocarbyl group and a substituted hydrocarbyl group, are disclosed. Also disclosed are methods of complexing the ligands with late transition metals to form catalyst complexes that catalyze polymerization reactions and/or Heck coupling reactions.

专利号:US-2009275616-A1
优先权日:2008-04-30
标 题 :Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues

专利号:CN-111362961-A
优先权日:2020-04-29
标题:A kind of method for asymmetric synthesis of glabridin with optical purity

专利号:CN-111362961-B
优先权日:2020-04-29
标题:A kind of method for asymmetric synthesis of glabridin with optical purity