CAS: 129512-75-0; Cis-1-Benzoyl-4-Hydroxy-L-Proline
- 英文名称Cis-1-Benzoyl-4-Hydroxy-L-Proline
- 中文名称顺式-1-苯甲酰-4-羟基-L-脯氨酸
- IUPAC名称(2S,4S)-1-benzoyl-4-hydroxypyrrolidine-2-carboxylic acid
- 其它别名Trans-1-Benzoyl-4-Hydroxy-L-Proline; Trans-1-Benzoyl-4-Hydroxyl-L-Proline; (2S,4R)-1-Benzoyl-4-Hydroxypyrrolidine-2-Carboxylic Acid; Cis-1-Benzoyl-4-Hydroxy-L-Proline; L-Proline, 1-Benzoyl-4-Hydroxy-, (4S)-; (2S,4R)-1-Benzoyl-4-Hydroxypyrrolidine-2-Carboxylicaci; Trans-1-Benzoyl-4-Hydroxy-L-Proline Usp/ep/bp; (4R)-1-Benzoyl-4-Hydroxy-L-Proline
- CAS编号129512-75-0
- MFCD编号:MFCD09834148
- 分子式:C12H13NO4分子量:235.24
- 产品CID: 455660
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
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1301738-43-1 120806-96-4 31560-21-1物理性质
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海关参考信息
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专利信息
专利号:EP-2019097-A1
优先权日:2007-07-25
标 题 :Process for preparing (alphaS)-alpha-(2-methylpropyl)-2-(1-piperidinyl)benzenemethanamine
发明人：MALLIKARJUNA REDDY KARURU; JAYATI MITRA; SIVAKUMARAN MEENAKSHISUNDERAM; RAMESH DANDALA
权利人:AUROBINDO PHARMA LTD
摘要:The present invention relates to a process for the preparation of (αS)-α-(2-methylpropyl)-2- (1-piperidinyl)benzenemethanamine of Formula I,n nwhich is a key intermediate for the synthesis of Repaglinide.
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合成参考文献
参考文献:10.1055/s-2006-956499
摘要:Zhai H, Ma Z. A Concise Formal Synthesis of Unnatural (+)-Aphanorphine from (2S,4R)-4-Hydroxyproline. Synlett. 2007 Jan;2007(1):0161–3. doi: 10.1055/s-2006-956499.
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