专利号:EP-4008687-A1 优先权日:2020-12-02 标 题:A method for the large scale synthesis of metal oxide nanosheets, and their uses 发明人:VINCENT MEWIN; ETACHERI VINODKUMAR 权利人:FUNDACION IMDEA MAT 摘要:The present invention relates to a rapid, scalable and inexpensive method for the synthesis of metal oxide nanosheets; the uses of the metal oxide nanosheets as electrode active materials and as catalyst; an electrode comprising the metal oxide nanosheets, a process for producing the electrode, a cell comprising the electrode and an energy storage and/or delivery system.
专利号:US-6376475-B1 优先权日:1997-05-30 标 题 :Control of immune responses by modulating activity of glycosyltransferases 发明人:MARTH JAMEY D; PAULSON JAMES C 权利人:ABARON BIOSCIENCES INC; UNIV CALIFORNIA 摘要:The invention provides methods for inhibiting immune responses by inhibiting the biosynthesis of the sialyl galactosides that are involved in immune responses. In particular, B lymphocyte-mediated immune responses are mediated by interfering with synthesis of α2,6 sialylgalactosides, while T lymphocyte-mediated immune responses are inhibited by blocking synthesis of α2,3 sialylgalactosides. The inhibition is accomplished by, for example, inhibiting the activity of a glycosyltransferase involved in synthesis of the respective sialyl galactoside.
专利号:US-2024309142-A1 优先权日:2023-03-17 标题 :Capped block copolymers, their synthesis, manufacture, and methods of use 发明人:MAN VICTOR FUK-PONG; LI XIAOJIN HARRY; CHEN YIQING; PU GANG; HUNT JR CLINTON 权利人:ECOLAB USA INC 摘要:This disclosure relates to capped block copolymers, preferably reverse block copolymers capped with a hydrophobic group. Preferred hydrophobic groups include benzyl groups and silyl groups. In a preferred embodiment, the reverse block copolymer has at least two arms, wherein each arm is capped with a hydrophobic group. The disclosure also provides for the synthesis of the capped block copolymers as well as methods of using the capped block copolymers for defoaming and antifoaming applications.
专利号:US-9149659-B2 优先权日:2012-11-14 标题 :Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles 发明人:PUJOS MURIEL; BERNINI DOROTHEE; ROBERT CECILE; DOUCET OLIVIER 权利人:COTY GERMANY GMBH 摘要:The present invention relates to a skin composition which has an excellent effect on smoothing or repairing wrinkles. The composition comprises Palmitoyl Tripeptide-38 (Palmitoyl-Lysyl-Dioxymethionyl-Lysine) and Piper nigrum (Pepper) seed Extract which combination has been found to result in a synergistic effect on hyaluronan synthase 1 (HAS1) mRNA expression in human fibroblasts. The hyaluronan synthase is responsible for the synthesis of hyaluronan (hyaluronic acid) in skin. Hyaluronic acid is a constituent of the extracellular matrix of the skin and responsible for space filling, tissue repair and retention of moisture.
专利号:US-5811302-A 优先权日:1992-08-13 标 题 :Bioactive material template for in vitro synthesis of bone tissue 发明人:DUCHEYNE PAUL; EL-GHANNAM AHMED; SHAPIRO IRVING 权利人:UNIV PENNSYLVANIA 摘要:Novel non-crystalline, porous bioactive glass and ceramic materials that permit the in vitro formation of bone tissue when exposed to a tissue culture medium and inoculated with cells are disclosed. The present invention also discloses methods of treating bioactive glass materials to control pH so that when the glass is exposed to a tissue culture medium and then inoculated with cells, bone tissue growth occurs in vitro. The glass material disclosed is preferably formed from SiO 2 , CaO, Na 2 O and P 2 O 5 and the porous, non-crystalline structure is most preferably created by melting the constituents, cooling and pulverizing the resulting glass, and then forming and hot pressing the powder. The glass of the present invention may be formed to produce templates that are useful for various indications, as well as granules that may be formed into a paste.
专利号:WO-2004074215-A1 优先权日:2003-02-03 标 题 :Process for preparation of clopidogrel, its salts and pharmaceutical compositions 发明人:NADKARNI SUNIL SADANAND; PATEL HASMUKH MATHURBHAI 权利人:NADKARNI SUNIL SADANAND; PATEL HASMUKH MATHURBHAI 摘要:The invention discloses an improved process for racemization of methyl (R)Â(-) alpha-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetate , a stereoisomer formed in the synthesis of clopidogrel i.e. methyl (S)-(+)-alpha (2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetate or its salts. The invention is also for an improved process for production of clopidogrel or its pharmaceutically acceptable salts. The invention further discloses novel clopidogrel salts and pharmaceutical compositions comprising them.