CAS: 55758-32-2; 6-Fluoropyridin-3-Ol

相似化合物

209328-85-8 174669-74-0 136888-79-4

上下游产品

CAS号351019-18-6 6-氟-3-吡啶硼酸 | CAS号766-11-0 5-溴-2-氟吡啶 | CAS号209328-51-8 3-Pyridinol,6-f... | CAS号444120-95-0 2-氟吡啶-5-硼酸频哪醇酯 | CAS号129034-38-4 6-碘-3-羟基吡啶

2-氟-5-氨基吡啶置于盐酸,Trifluoroborane Diethyl Ether体系中,用 Sodium Hydroxide,乙二醇二甲醚,Aqueous Na2 Co3,乙酸酐,正戊烷 作为反应溶剂,化学反应生成 2-氟-5-羟基吡啶
参考文献:3-Pyridyl Enantiomers And Their Use As Analgesics
标题:3-Pyridyl Enantiomers And Their Use As Analgesics
摘要:本发明涉及一种控制哺乳动物(包括人类)疼痛的方法,包括向需要治疗的哺乳动物或患者施用公式i所选化合物:##str1##或其药学上可接受的盐.该发明还涉及上述公式i的选定(R)和(S)化合物,其可用作镇痛剂,神经细胞凋亡抑制剂和抗炎药.

专利信息

专利号:US-9856241-B2
优先权日:2013-07-03
标 题:Substituted benzofuranyl and benzoxazolyl compounds and uses thereof
发明人：BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to substituted benzofuranyl and substituted benzoxazolyl compounds, and more particularly to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of Structural Formula (A), or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders.