CAS: 550-28-7; Amisometradine
该化合物是一种化学化合物,其特点是其火水环结构,这是一个由六人组成的芳香环,含有位于1和3号位置的两种氮原子,该化合物具有6个位置的氨基组和位于3号位的甲基组,有助于其基本性和潜在反应性.在1号位置上存在2-甲基-2-丙基-1-yl替代成分,这引入了双联结,增强了其反应性,使之适合各种化学转化.该化合物经常因其生物活动,特别是医学化学活动而进行研究,在那里可能表现出抗微生物或抗脉冲效应等特性,其溶性能和稳定性取决于pH值和溶剂条件,后者是其应用于研究和工业的重要因素.总体而言,6-Amino-3-甲基-1-(2-甲基-2-2-progen-1-y)-2,4(1H,3H)-pyrimidinedone是一种在各种化学和制药环境中具有巨大潜力的多种特性化合物.
- 英文名称Amisometradine
- 中文名称阿米美啶
- IUPAC名称6-amino-3-methyl-1-(2-methylallyl)pyrimidine-2,4(1H,3H)-dione
- 其它别名6-Amino-3-Methyl-1-(2-Methyl-2-Propenyl)Pyrimidine-2,4(1H,3H)-Dione; 6-Amino-3-Methyl-1-(2-Methylallyl)Uracil; Aminoisometradine; Rolicton; 6-Amino-3-Methyl-1-(2-Methylallyl)Pyrimidine-2,4-Quinone; 6-Amino-3-Methyl-1-(2-Methylprop-2-Enyl)Pyrimidine-2,4-Dione; 6-Azanyl-3-Methyl-1-(2-Methylprop-2-Enyl)Pyrimidine-2,4-Dione; Amisometradine
- CAS编号550-28-7
- MFCD编号:MFCD00867343
- EINECS号:208-980-3
- FDA UNII编号:30973N61ZF
- 分子式:C9H13N3O2分子量:195.22
- 产品CID: 2504676
- 产品分类有机原料 → 有机杂环化合物 → 二嗪类
物理性质
MSDS等安全信息
上下游产品
CAS号874517-48-3 N-cyanoacetyl-N... | CAS号77-78-1 硫酸二甲酯合成工艺路线路线简述
📜Methallyl-Urea置于sodium Hydroxide,乙醇,乙酸酐体系中,化学反应生成 阿米美啶
参考文献:Synthesis Of 1-Mono-And 1,3-Di-Substituted 6-Aminouracils. Diuretic Activity
标题:Synthesis Of 1-Mono-And 1,3-Di-Substituted 6-Aminouracils. Diuretic Activity
摘要:
DOI:10.1021/jo50006A010
海关参考信息
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- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.
专利号:US-10814013-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A1
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:US-2008107598-A1
优先权日:2006-10-05
标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications
专利号:AU-2007308022-B2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: VAN ARMAN CG, DETTELBACH HR, KAGAWA CM. A uracil diuretic: amisometradine (rolicton). Arch Int Pharmacodyn Ther. 1960 Jul 1;126:400-11.
3: BRUERA EF, BLANCO F, FERRARIO R, SCHILIAGGI E, GASPARY FV. [Comparative study of the diuretic effect of a mercurial, chlorothiazide & amisometradine]. Sem Med. 1959 Mar 26;114(13):404-7 passim. Spanish.
6: BELLE MS. Clinical experience with amisometradine (rolicton) on ambulatory patients. Am Heart J. 1958 Jan;55(1):114-9.
合成参考文献
摘要:Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals, 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989, 11(79), 1989
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