CAS: 5345-54-0; 3-Chloro-4-Methoxyaniline

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CAS号4920-79-0 2-氯-4-硝基苯甲醚 | CAS号217314-34-6 1-(3-chloro-4-m... | CAS号766-51-8 邻氯苯甲醚 | CAS号135050-44-1 3-氯-4-碘苯胺 | CAS号19937-59-8 甲氧隆 | CAS号3964-54-3 N-(3-氯-4-羟基苯基)乙酰胺 | CAS号21778-81-4 5-甲氧基-1H-吲哚-2-甲醛 | CAS号18093-12-4 3-chloro-4-meth... | CAS号104-94-9 对甲氧基苯胺 | CAS号7073-42-9 N-(3-氯-4-甲氧基苯基)乙酰胺 | CAS号5883-96-5 5-甲氧基-2-苯基-1H-吲哚 | CAS号153865-29-3 SPIRO[3H-CARBAZ... | CAS号160088-54-0 5-Chloro-4-meth... | CAS号35556-81-1 6-methoxy-1,2,3... | CAS号160088-53-9 N-(5-氯-4-甲氧基-2-...

📜2-氯苯甲醚置于2,2,6,6-四甲基哌啶氧化物,3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium Tetrafluoroborate,氧气,氨基甲酸铵体系中,用 水,1,2-二氯乙烷 作为反应溶剂,化学反应 24.0H,以33%的收率获得产物3-氯-4-甲氧基苯胺
参考文献:通过光氧化还原催化的位点选择性芳烃 Ch 胺化
标题:通过光氧化还原催化的位点选择性芳烃 Ch 胺化
摘要:为芳基 Cn 键合开辟道路 药物化学家喜欢将 N 键添加到芳环的 C 原子上以制造生物活性化合物.通过利用可见光中的能量,Romero 等人.建立这些联系并将 Ch 转化为 Cn 键.他们使用一种吸收蓝色的吖啶离子来激活一个环 C 以供传入的 N 伙伴使用.然后,硝酰基自由基助催化剂 (Tempo) 对 H 原子向 O 的转移进行了编排.该反应适用于广泛的底物,包括作为 N 源的铵.科学,这个问题 P.1326 两种催化剂利用可见光和氧气形成药物研究中感兴趣的碳氮键基序.在过去的几十年里,有机金属交叉偶联化学已发展成为从预氧化起始材料组装复杂芳香族化合物的最可靠方法之一.最近,过渡金属催化的碳氢活化避免了对预氧化起始材料的需求,但这种方法因缺乏实用的胺化方案而受到限制.在这里,我们提出了通过光氧化还原催化进行芳香碳氢功能化的蓝图,并描述了该策略在芳烃胺化中的应用.一种基于有机光氧化还原的催
DOI:10.1126/science.Aac9895

专利信息

专利号:WO-2008103866-A1
优先权日:2007-02-22
标题 :Synthesis of indoles
发明人：TALLEY JOHN JEFFREY; RENZE JUERGEN T
权利人:MICROBIA INC; TALLEY JOHN JEFFREY; RENZE JUERGEN T
摘要:Method for preparing indoles, including methods that permit high yield production of particular compounds, are described.

专利号:US-2022259212-A1
优先权日:2019-07-11
标题:Inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan 2,3-dioxygenase
发明人：BOSS CHRISTOPH; CREN SYLVAINE; KIMMERLIN THIERRY; LOTZ-JENNE CARINA; POTHIER JULIEN; TIDTEN-LUKSCH NAOMI
权利人:IDORSIA PHARMACEUTICALS LTD
摘要:The present invention relates to compounds of Formula (I) inhibiting indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO) enzymes. Further, their synthesis and their use as medicaments in the treatment of inter alia cancer is disclosed.

专利号:US-2005234244-A1
优先权日:2004-04-20
标题:Synthesis of COX-2 and FAAH inhibitors
发明人：BARTOLINI WILMIN; CALI BRIAN M; CHEN BARBARA; CHIEN YUEH-TYNG; CURRIE MARK G; MILNE G T; PEARSON JAMES P; TALLEY JOHN J; ZIMMERMAN CRAIG
权利人:BARTOLINI WILMIN; CALI BRIAN M; CHEN BARBARA; CHIEN YUEH-TYNG; CURRIE MARK G; MILNE G T; PEARSON JAMES P; TALLEY JOHN J; ZIMMERMAN CRAIG
摘要:Methods for preparing indoles that are useful COX-2 inhibitors and intermediates useful in such methods are described.

专利号:WO-0053313-A2
优先权日:1999-03-09
标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries

专利号:US-4136033-A
优先权日:1969-11-07
标 题:6-hydroxypyridone-2 compounds having a cationic group in the 3-position
发明人：STEINEMANN WILLY
权利人:SANDOZ LTD
摘要:Compounds of the formula ##STR1## wherein K.sup.⊕ is a cationic group, preferably heterocyclic, n R is hydrogen or an organic radical, preferably alkyl, phenyl or acyl, n R 1 is hydrogen, hydrocarbyl, substituted hydrocarbyl, heterocyclyl, substituted heterocyclyl, amino or substituted amino, and n A.sup.⊖ is an anion, n Are useful as intermediates in the synthesis of azo dyes of the formula ##STR2## wherein D is an aromatic carbocyclic or heterocyclic diazo component radical, and n K.sup.⊕, r, r 1 and A.sup.⊖ are as defined above.

专利号:US-6417195-B1
优先权日:1999-02-22
标题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人：LEBL MICHAL
权利人:LION BIOSCIENCE AG
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compounds.