CAS: 4192-90-9; 1-(2,6-Dihydroxy-4-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Phenyl)-3-(4-Hydroxyphenyl)Propan-1-One
该化合物是一种化学化合物,属于氟氯素类,具体地说是一种氟氯素胶片,主要来自各种植物来源,特别是豆类家族的植物来源;Trilobatin的特点是其甘蓝结构,由一种与糖糖豆相连的氟氯素组成;该化合物展示了一系列生物活动,包括抗氧化特性,有助于其潜在的健康利益;此外,已经研究过三丁烯的抗炎和抗微生物效应;其溶性特征因使用的溶剂不同而不同,由于糖成分的存在,它通常在极地溶剂中溶性更大;与许多氟氯素一样,三丁烯可能在植物色素和紫外线保护方面发挥作用;正在进行进一步的研究,以充分阐明其在制药和营养素方面的行动和潜在应用机制.
- 英文名称1-(2,6-Dihydroxy-4-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Phenyl)-3-(4-Hydroxyphenyl)Propan-1-One
- 中文名称三叶苷
- IUPAC名称1-(2,6-dihydroxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one
- 其它别名Prunindihydrochalcone; 1-[4-(β-D-Glucopyranosyloxy)-2,6-Dihydroxyphenyl]-3-(4-Hydroxyphenyl)-1-Propanone; Phloretin 4'-Glucoside; P-Phloridzin; P-Phlorizin; Trilobatin; Trilobatin(Sh); Trilobatin, , From Leaf Of Strigose Hydrangea
- CAS编号4192-90-9
- MFCD编号:MFCD21333313
- EINECS号:111-915-0
- FDA UNII编号:23298I791N
- 分子式:C21H24O10分子量:436.41
- 产品CID: 1432842
- 产品分类天然产物 → 查尔酮类化合物
物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
CAS号1133352-99-4 (2R,3R,4S,5R,6S... | CAS号18916-17-1 柚皮苷二氢查尔酮 | CAS号10236-47-2 柚皮苷 | CAS号50376-43-7 NARINGIN CHALCONE | CAS号60-82-2 根皮素合成工艺路线路线简述
📜Naringin置于硫酸,10 Wt% Pd(Oh)2 On Carbon,氢气,Sodium Hydride体系中,用 甲醇,水,乙酸乙酯,N,N-二甲基甲酰胺,Mineral Oil 作为反应溶剂,化学反应 28.0H,反应生成 三叶甙
参考文献:由柚皮苷经关键蛋白中间体从柚皮苷合成三叶苷:柚皮苷中α-鼠李糖苷键在改良条件下的酸性水解.
标题:由柚皮苷经关键蛋白中间体从柚皮苷合成三叶苷:柚皮苷中α-鼠李糖苷键在改良条件下的酸性水解.
摘要:由市售柚皮苷分三步合成三叶苷[4'-(β-D-吡喃葡萄糖基氧基)-2',4",6'-三羟基二氢查尔酮],总产率为30%.关键步骤是酸催化位点通过使用高压蒸汽灭菌器,在受控条件下,与柚皮苷有关的新橙皮糖中末端α-鼠李糖吡喃糖苷键的选择性水解.
DOI:10.1080/09168451.2018.1482455
海关参考信息
- 2902600000-乙苯
2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-12071646-B2
优先权日:2014-09-11
标 题 :Cells comprising mogroside pathway enzymes and uses thereof
发明人：ITKIN MAXIM; DAVIDOVICH-RIKANATI RACHEL; COHEN SHAHAR; PORTNOY VITALY; DORON-FAIGENBOIM ADI; PETREIKOV MARINA; SHEN SHMUEL; TADMOR YAAKOV; BURGER YOSEF; LEWINSOHN EFRAIM; KATZIR NURIT; SCHAFFER ARTHUR A; OREN ELAD
权利人:THE STATE OF ISRAEL MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT AGRICULTURAL RES ORGANIZATION ARO VO
摘要:Isolated mogroside and mogrol biosynthetic pathway enzyme polypeptides useful in mogroside biosynthesis are provided. Mogroside biosynthetic pathway enzymes of the invention include squalene epoxidase (SE), epoxy hydratase (EH), cytochrome p450 (Cyp), cucurbitadienol synthase (CDS) and udp-glucosyl-transferase (UGT), Also provided are methods of producing a mogroside using the isolated mogroside and mogrol biosynthetic enzyme polypeptides, the methods comprising contacting a mogrol and/or a glycosylated mogrol (mogroside) with at least one UDP glucose glucosyl transferase (UGT) enzyme polypeptide of the invention catalyzing glucosylation of the mogrol and/or the glucosylated mogrol to produce a mogroside with an additional glucosyl moietie(s), thereby producing the mogroside. Alternatively or additionally provided is a method of synthesizing a mogrol, the method comprising contacting a mogrol precursor substrate with one or more mogrol biosynthetic pathway enzyme polypeptides as described herein catalyzing mogrol synthesis from the mogrol precursor substrate, thereby synthesizing the mogrol.
专利号:CN-120130286-A
优先权日:2025-03-13
标题:Method for promoting growth of lithocarpus littoralis leaves, synthesis of dihydrochalcone and reduction of heavy metal content
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1. Stander, M.A., Van Wyk, B.-E., Taylor, M.J.C., et al. Analysis of phenolic compounds in rooibos tea (Aspalathus linearis) with a comparison of flavonoid-based compounds in natural populations of plants from different regions. J. Agric. Food Chem. 65(47), 10270-10281 (2017). 2. Qin, X., Xing, Y.F., Zhou, Z., et al. Dihydrochalcone compounds isolated from crabapple leaves showed anticancer effects on human cancer cell lines. Moleules 20(12), 21193-21203 (2015). 3. Yang, W.-M., Liu, J.-K., Qin, X.-D., et al. Antioxidant activities of three dihydrochalcone glucosides from leaves of Lithocarpus pachyphyllus. Z. Naturforsch. C. 59(7-8), 481-484 (2004). 4. Gao, J., Liu, S., Xu, F., et al. Trilobatin protects against oxidative injury in neuronal PC12 cells through regulating mitochondrial ROS homeostasis mediated by AMPK/Nrf2/Sirt3 signaling pathway. Front. Mol. Neurosci.11:267, (2018). 5. Yin, S., Zhang, X., Lai, F., et al. Trilobatin as an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope. FEBS Lett. 592(13), 2361-2377 (2018).
合成参考文献
参考文献:10.1016/j.phytochem.2009.11.004
摘要:Dugé de Bernonville T, Guyot S, Paulin JP, Gaucher M, Loufrani L, Henrion D, Derbré S, Guilet D, Richomme P, Dat JF, Brisset MN. Dihydrochalcones: Implication in resistance to oxidative stress and bioactivities against advanced glycation end-products and vasoconstriction. Phytochemistry. 2010 Mar;71(4):443–52. doi: 10.1016/j.phytochem.2009.11.004.
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