CAS: 24867-26-3; 2,4-Diamino-6-Piperidinopyrimidine

该化合物是一种糖浆衍生物,在制药和化妆品研究中具有显著应用,其结构上与pronoxidil相似,表明它在促进发型增长方面具有潜在效用,尽管它缺乏N-氧化物组,这可能会影响其药用动力学特征.化合物在标准条件下表现出稳定性,并展示普通有机溶剂的溶解性,促进配方开发.其管状动物会有助于增加亲脂性,有可能改善皮肤吸收.研究人员在生物活动研究的模拟合成中重视这种中间体的多变性.分析方法确认高纯度,使其适合临床前的调查.还需要进一步研究,以充分阐明其药理机制和治疗潜力.

结构式图片

欧盟法规

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上下游产品

CAS号110-89-4 六氢吡啶 | CAS号156-83-2 2,4-二氨基-6-氯嘧啶

合成工艺路线路线简述

  • 合成目标产物 2,4-Diamino-6-Piperidinopyrimidine 主要起始原料 Piperidine And 4-Chloro-2,6-Diaminopyrimidine
  • (文献来源)合成步骤主要原料 Piperidine 和 4-Chloro-2,6-Diaminopyrimidine
📜米诺地尔 以97%的收率获得
参考文献:Mccall J. M.; Tenbrink R. E.,Synthesis,1975,No 5,335-336
标题:Mccall J. M.; Tenbrink R. E.,Synthesis,1975,No 5,335-336

海关参考信息

专利信息


专利号:US-7750090-B2
优先权日:2003-01-30
标 题:Moleculary imprinted polymers for extraction of components from foodstruffs
发明人:SELLERGREN BOERJE; MANESIOTIS PANAGIOTIS; HALL ANDREW J
权利人:MIP TECHNOLOGIES AB
摘要:The present invention relates to a novel class of water compatible molecularly imprinted polymers (AquaMIPs) capable of selectively binding target molecules such as riboflavin, or analogues thereof, in water or aqueous media, their synthesis and use thereof in food processing and extraction or separation processes.

专利号:US-8858968-B2
优先权日:2005-12-05
标题 :Use of tyrosine-arginine dipeptide and niacinamide as substance P antagonist
发明人:POTIN ANTHONY
权利人:POTIN ANTHONY; OREAL
摘要:Use of the combination of the tyrosine-arginine dipeptide or derivatives thereof and of niacinamide as a substance P antagonist for treating red blotches on the skin, skin oedema and sensitive skin. Use of this combination for the preparation of a composition for use in treating disorders associated with an excess synthesis and/or release of substance P.

专利号:WO-9514468-A1
优先权日:1993-11-29
标题:Blocking utilization of tetrahydrobiopterin to block induction of nitric oxide synthesis

专利号:EP-0730451-A4
优先权日:1993-11-29
标题 :INHIBITION OF THE USE OF TETRAHYDROBIOPTERIN TO BLOCK THE INDUCTION OF NITRIC OXIDE SYNTHESIS

专利号:EP-0730451-A1
优先权日:1993-11-29
标题 :Blocking utilization of tetrahydrobiopterin to block induction of nitric oxide synthesis

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:B. Roth and J.Z. Strelitz. J. Org. Chem. 35, 2696 (1970).
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