CAS: 1073-62-7; Benzylhydrazine Hydrochloride

相似化合物

20570-96-1 21075-83-2 2644-70-4

上下游产品

N'-benzylhydrazinecarboxylic acid tert-butyl ester benzaldehyde benzylhydrazone tert-butyl 1-benzylhydrazine-1-carboxylate N-benzyl-N'-[(tert-butoxy)carbonyl](tert-butoxy)carbohydrazide1-benzyl-3,5-dimethyl-1H-pyrazole 2-benzylthiosemicarbazide 2-benzyl thiosemicarbazideN2-benzyl thiosemicarbazide 1-Ethansulfonyl-1-benzyl-2-benzyliden-hydrazin

专利信息

专利号:US-7244753-B2
优先权日:2002-07-29
标 题:Cyclooxygenase-2 selective inhibitors, compositions and methods of use
发明人：GARVEY DAVID S; KHANAPURE SUBHASH P; RANATUNGE RAMANI R; RICHARDSON STEWART K; SCHROEDER JOSEPH D
权利人:NITROMED INC
摘要:The invention describes novel cyclooxygenase 2 (COX-2) selective inhibitors and novel compositions comprising at least one cyclooxygenase 2 (COX-2) selective inhibitor, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or at least one therapeutic agent. The invention also provides novel kits comprising at least one COX-2 selective inhibitor, optionally nitrosated and/or nitrosylated, and, optionally, at least one nitric oxide donor, and/or, optionally, at least one therapeutic agent. The novel cyclooxygenase 2 selective inhibitors of the invention can be optionally nitrosated and/or nitrosylated. The invention also provides methods for treating inflammation, pain and fever; for treating and/or improving the gastrointestinal properties of COX-2 selective inhibitors; for facilitating wound healing; for treating and/or preventing renal and/or respiratory toxicity; for treating and/or preventing other disorders resulting from elevated levels of cyclooxygenase-2; and for improving the cardiovascular profile of COX-2 selective inhibitors.

专利号:US-10329264-B2
优先权日:2015-07-31
标题 :Process for the preparation of isocarboxazid
发明人：DE FAVERI CARLA; HUBER FLORIAN ANTON MARTIN; ANTOLINI NICOLA
权利人:LUNDBECK PHARMACEUTICALS ITALY S P A
摘要:This invention relates to a novel chemical process for the synthesis of N′-benzyl-5-methylisoxazole-3-carbohydrazide (Isocarboxazid) which comprises reacting 5-methyl-3-isoxazole carboxylic acid ester with benzylhydrazine or a salt thereof in an aprotic organic solvent and in the presence of an organic base.

专利号:US-6297194-B1
优先权日:1999-02-02
标 题 :Production of phosphonopyrazoles
发明人：MILLER PAULA C; CURTIS JANE M; MOLYNEAUX JOHN M; OWEN THOMAS J
权利人:MONSANTO TECHNOLOGY LLC
摘要:Pyrazole compounds with activity as chemical hybridizing agents and methods for synthesis of such compounds are disclosed. These compounds are useful in producing hybrid wheat (Triticum aesativum) and other crops.

专利号:US-2002107401-A1
优先权日:2000-02-02
标题:Production of phosphonopyrazoles
发明人：MILLER PAULA C; CURTIS JANE M; MOLYNEAUX JOHN M; OWEN THOMAS J
权利人:MONSNTO TECHNOLOGY LLC
摘要:Novel compounds with activity as chemical hybridizing agents and methods for synthesis of such compounds are disclosed. These compounds are useful in producing hybrid wheat ( Triticum aesativum ) and other crops.

专利号:US-10226449-B2
优先权日:2013-12-20
标 题:Heterocyclic modulators of lipid synthesis and combinations thereof
发明人：HEUER TIMOTHY SEAN; OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; DUKE GREGORY; OHOL-GUPTA YAMINI; O'FARRELL MARIE
权利人:3 V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by dysregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.

专利号:US-9428502-B2
优先权日:2012-07-03
标题:Heterocyclic modulators of lipid synthesis
发明人：OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; WAGMAN ALLAN S
权利人:3-V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.