CAS: 10276-21-8; 4,4,6-Trimethyl-7-Oxabicyclo[4.1.0]Heptan-2-One

上下游产品

CAS号78-59-1 异佛尔酮 | CAS号471-01-2 3,5,5-三甲基-3-环己烯-1-酮 | CAS号84559-99-9 3,5,5-trimethyl... | CAS号4694-12-6 2,4,4-三甲基环戊酮 | CAS号527-54-8 3,4,5-三甲基苯酚 | CAS号4883-60-7 2-羟基-3,5,5-三甲基-... | CAS号10275-88-4 CYCLOPENTANECAR... | CAS号57696-89-6 烟酮 | CAS号5682-76-8 2-methoxy-3,5,5... | CAS号20624-63-9 3,3-dimethyl-5-... | CAS号115118-28-0 2(3H)-Furanone,... | CAS号78-59-1 异佛尔酮 | CAS号89768-14-9 3-hydroxy-3,5,5...

异佛尔酮置于二甲基二环氧乙烷体系中,用 二氯甲烷,丙酮 用作溶剂,化学反应 20.0H,以86%的收率获得氧化异佛尔酮
参考文献:α,β-不饱和酮,酸和酯的二甲基二环氧乙烷环氧化.
标题:α,β-不饱和酮,酸和酯的二甲基二环氧乙烷环氧化.
摘要:通过二甲基二环氧乙烷(作为丙酮溶液)的氧转移,以优异的收率分离出相应的环氧化物.
Doi:10.1016/s0040-4039(00)94547-7

专利信息

专利号:US-7122693-B2
优先权日:1988-04-11
标题 :Acetaldehyde acetal compounds, their synthesis, and uses thereof
发明人：BELLEAU EXECUTRIX OF ESTATE PI; DIXIT DILIP M; NGUYEN-BA NGHE
权利人:SHIRE BIOCHEM INC
摘要:The acetaldehyde compounds, 2-thiobenzoylacetaldehyde diethylacetal, 2-benzoyloxyacetaldehyde bis(2-methoxyethyl)acetal, 2-hydroxyacetaldehyde bis( 2-methoxyethyl)acetal, 2-thiobenzoylacetaldehyde bis(2-methoxy-ethyl)acetal, and 2-thioacetaldehyde bis(2-methoxyethyl)acetal, are useful as intermediates in the synthesis of substituted 1,3-oxathiolanes and substituted 1,3-dioxolanes.

专利号:WO-2020109533-A1
优先权日:2018-11-30
标 题:Process for selective synthesis of 4-hydroxyisophorone and 4-ketoisophorone by fungal peroxygenases
发明人：ARANDA OLIDEN Mª DEL CARMEN; DEL RÃ?O ANDRADE JOSÉ CARLOS; MARTÃ?NEZ FERRER Ã?NGEL TOMÃ?S; GUTIÉRREZ SUAREZ ANA
权利人:CONSEJO SUPERIOR INVESTIGACION
摘要:The process of the present invention relates to the biocatalytic transformation of isophorone (3,5,5-trimethylcyclohex-2-en-1-one) and 4-hydroxyisophorone by several unspecific peroxygenases produced by fungi. These biocatalysts, that only require H 2 O 2 or organic peroxides for activation, potentially represent a novel simple and environmentally friendly route for the production of isophorone derivatives, such as the high value products for the pharmaceutical and flavour and fragrance industry 4-hydroxyisophorone and 4-ketoisophorone.

专利号:US-12077801-B2
优先权日:2017-04-07
标 题:Regioselective hydroxylation of isophorone
发明人：BONRATH WERNER; SCHÃœRMANN MARTIN; TAVANTI MICHELE; PARMEGGIANI FABIO; TURNER NICHOLAS; MATTEVI ANDREA; CASSTELLANOS JOSE RUBEN
权利人:DSM IP ASSETS BV
摘要:The present invention relates to novel process for the production of ketoisophorone via biocatalytic conversion of isophorone, in particular a one-pot biocatalytic system for conversion of α-isophorone in a two-step oxidation process, with a first oxidation being catalyzed by a heme containing oxidoreductase such as a cytochrome P450 monooxygenase followed by another oxidation which can be either a chemical reaction or a biocatalytic reaction, in particular wherein the oxidation is catalyzed by an NAD(P) or NADP(H)-dependent oxidoreductase. The invention further provides polypeptides and nucleic acid sequences coding for cytochrome P450 monooxygenase with modified (higher) substrate selectivity, total turnover numbers and/or (re)activity compared to the wild-type enzyme. Ketoisophorone is useful as building block in the synthesis of vitamins and carotenoids.

专利号:US-2003087918-A1
优先权日:1988-04-11
标题 :Synthesis of substituted 1,3-dioxolanes and substituted 1,3-oxathiolanes with antiviral properties

专利号:EP-3660147-A1
优先权日:2018-11-30
标 题:Process for selective synthesis of 4-hydroxyisophorone and 4-ketoisophorone by fungal peroxygenases