CAS: 102130-84-7; Nemadectin

上下游产品

CAS号102042-12-6 LL-F28249λ

📜5-Oxo(4-Nitrobenzoyl)-2,3-Methoxime Nimoxectine置于盐酸,甲醇,Sodium Tetrahydroborate,Sodium Hydroxide体系中,用 1,3-二噁烷,二氯甲烷,水 用作溶剂,化学反应 12.0H,反应生成奈马克丁
参考文献:一种制备高含量尼莫克汀的方法
标题:一种制备高含量尼莫克汀的方法
摘要:本发明公开了一种制备高含量尼莫克汀的方法,属于有机化学技术领域.该方法以结晶提纯后的5‑氧(保护基)‑23‑氧代尼莫克汀或5‑氧(保护基)‑23‑甲肟尼莫克汀为原料,经过脱肟,还原,去保护和硅胶柱分离,获得高含量尼莫克汀,所得尼莫克汀HPLC纯度>=95.0A%,含量>=93.0Wt.%.该方法应具有后处理简单,柱分离次数少以及尼莫克汀含量高等优点.

专利信息

专利号:US-7067286-B2
优先权日:1998-11-20
标 题 :Cystobacterineae host cells containing heterologous PKS genes for the synthesis of polykedtides
发明人：JULIEN BRYAN; KATZ LEONARD; KHOSLA CHAITAN
权利人:KOSAN BIOSCIENCES INC
摘要:Recombinant host cells of the suborder Cystobacterineae, genus Stizmatella , containing recombinant expression vectors that encode heterologous epothilone polyketide synthase (PKS) genes and can produce epothilones at high levels are provided.

专利号:RU-2030416-C1
优先权日:1989-09-11
标题:Method of synthesis of 23-(c1-c6-alkyloximes)-l,l-f-28249

专利号:US-6902913-B2
优先权日:1997-04-30
标题:Recombinant narbonolide polyketide synthase
发明人：BETLACH MELANIE C; BETLACH MARY; MCDANIEL ROBERT; TANG LI
权利人:KOSAN BIOSCIENCES INC
摘要:Recombinant DNA compounds that encode all or a portion of the narbonolide polyketide synthase are used to express recombinant polyketide synthase genes in host cells for the production of narbonolide, narbonolide derivatives, and polyketides that are useful as antibiotics and as intermediates in the synthesis of compounds with pharmaceutical value.

专利号:US-2008176865-A1
优先权日:2005-06-15
标 题:Substituted arylpyrazoles
发明人：BILLEN DENIS; BOYLE JESSICA; CRITCHER DOUGLAS JAMES; GETHIN DAVID MORRIS; HALL KIM THOMAS; KYNE GRAHAM MICHAEL
权利人:PFIZER LTD
摘要:This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.

专利号:US-7645786-B2
优先权日:2005-06-15
标题:Substituted arylpyrazoles
发明人：BILLEN DENIS; BOYLE JESSICA; CRITCHER DOUGLAS JAMES; GETHIN DAVID MORRIS; HALL KIM THOMAS; KYNE GRAHAM MICHAEL
权利人:PFIZER
摘要:This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.

专利号:US-7803832-B2
优先权日:2004-03-18
标题 :N-(1-arylpyrazol-4L)sulfonamides and their use as parasiticides
发明人：CRITCHER DOUGLAS JAMES; WALSHE NIGEL DEREK ARTHUR; LAURET CHRISTELLE
权利人:PFIZER; PFIZER PROD INC
摘要:The invention relates to a sulfonamide compound of formula (I) or a pharmaceutically, veterinarily or agriculturally acceptable salt or solvate thereof, where the groups R 1 -R 5 are described in the description, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.