- 英文名称((4R,5R)-2,2-Dimethyl-1,3-Dioxolane-4,5-Diyl)Dimethanol
- 中文名称(-)-2,3-O-异亚丙基-D-苏糖醇
- IUPAC名称((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)dimethanol
- 其它别名(4R,5R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4,5-Dimethanol; (4R,5R)-(-)-4,5-Bis(Hydroxymethyl)-2,2-Dimethyl-1,3-Dioxolane; ((4R,5R)-5-Hydroxymethyl-2,2-Dimethyl-[1,3]Dioxolan-4-yl)-Methanol; [(4R,5R)-5-(Hydroxymethyl)-2,2-Dimethyl-1,3-Dioxola
- CAS编号73346-74-4
- MFCD编号:MFCD00009761
- EINECS号:277-391-1
- 分子式:C7H14O4
- 分子量:162.18
- 产品CID: 1720238
- 产品分类生物化工 → 糖类化合物 → 单糖
物理性质
- 熔点42-48 °C
- 沸点335.9±0.0 °C at 760 mmHg
- 闪点111.9±20.4 °C
- 密度1.1±0.1 g/cm3
- PH:-3.1 º (c=5, CHCl3 26 °C)
- pKa:13.90±0.10(预测)
- PSA:58.92
- LogP:-0.01
- 旋光度-3.1º(C=5,CHCL326ºC)
- 折射率1.443
- 蒸汽压0.0±1.6 mmHg at 25°C
- 溶解性Chloroform, Dichloromethane, Ethyl Acetate, Thf
- 敏感性吸潮
- 外观形态黄色油状物
- 储存条件惰性气氛,存放于冰箱中, -20°C
- 产品应用该化合物用于合成光学活性对对丙基2,3-丁二烯基苯基,它与甲苯-4-硫磷基氯化物发生反应,以获得O2,O3-异丙基-O1,O4-双(甲乙烯-4-舒尔芬基)-D甲基苯基.
上下游产品
CAS号37031-29-1 (-)-二甲基-2,3-邻异丙... | CAS号73346-73-3 (4S,5S)-2,2-二甲基... | CAS号3969-84-4 3,4-O-异亚丙基-D-甘露糖醇 | CAS号59779-75-8 (R,R)-O,O-异丙基酒石酸二乙酯 | CAS号5754-27-8 (4S,5S)-2,2-dim... | CAS号77-76-9 2,2-二甲氧基丙烷 | CAS号3969-59-3 三丙酮甘露糖醇 | CAS号109715-58-4 2,2-dimethyl-3a... | CAS号51064-65-4 1,4-甲苯磺酰基-2,3-异... | CAS号73711-65-6 ((4R,5R)-5-(hyd... | CAS号139165-54-1 1,4-二氯丁烷-2S-3S-二醇Mannitol Triacetonide置于sodium Tetrahydroborate,Sodium Periodate,溶剂黄146体系中,化学反应 4.5H,反应生成 (-)-2,3-O-亚异丙基-D-苏力糖醇
参考文献:Holy,Antonin,Collection Of Czechoslovak Chemical Communications,1982,Vol. 47,# 1,P. 173-189
标题:Holy,Antonin,Collection Of Czechoslovak Chemical Communications,1982,Vol. 47,# 1,P. 173-189
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示:海关信息按照顺序优先匹配,如需确认的海关信息,请参考相关资料。
- 详情请参考:📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10266565-B2
优先权日:2011-04-12
标 题 :Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use
发明人:BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG-EUN
权利人:BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG EUN; THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
摘要:Novel compounds are provided that bind to polo-like kinases through the polo-box domain. In certain embodiments, the novel compounds are PEGylated peptides. The PEGylated peptides in accordance with the invention demonstrate high PBD-binding affinity. In certain embodiments, the PEGylated peptides have also achieved activities in whole cell systems. The invention also provides compounds that bind polo-like kinases through the polo-box domain and possess reduced anionic charge. Further provided are methods of design and/or synthesis of the PEGylated peptides and methods of use thereof. The invention provides methods of use of the compounds and methods of synthesis of the compounds.
专利号:US-8580975-B2
优先权日:2008-01-11
标 题:Synthesis of macrocyclic cancer chemotherapy agents and methods of use
发明人:GHOSH ARUN K; XU XIAOMING
权利人:GHOSH ARUN K; XU XIAOMING; PURDUE RESEARCH FOUNDATION
摘要:Herein are described a process for forming a quaternary carbon useful in the preparation of macrolactones, an enantioselective synthesis of (+)-peloruside A, and methods for treating a patient in need of relief from cancer or a cancer-related disease. The described processes are useful for preparing compounds containing quaternary carbons, including structural analogs and derivatives of peloruside A.
专利号:US-5880295-A
优先权日:1994-02-16
标 题 :Process for the preparation of diamine intermediates useful in the synthesis of HIV protease inhibitors
发明人:KALTENBACH III ROBERT FRANK
权利人:DU PONT PHARM CO
摘要:The present invention provides a process for the preparation of compounds of formula (V) below, and analogs thereof, which are useful as intermediates for the synthesis of HIV protease inhibitors, including cyclic ureas. ##STR1##
专利号:WO-2009089450-A1
优先权日:2008-01-11
标题:Synthesis of macrocyclic cancer chemotherapy agents and methods of use
专利号:EP-2242502-A1
优先权日:2008-01-11
标题:Synthesis of macrocyclic cancer chemotherapy agents and methods of use
专利号:US-6573388-B1
优先权日:1999-08-18
标 题:Ethylaziridine derivatives and their preparation methods
发明人:KIM BYUNG MOON; BAE SUNG JIN; SO SOON MOK; KANG JAE SUNG; LEE JOONG HWAN
权利人:SAMCHULLY PHARM CO LTD
摘要:This invention is related to new ethylaziridine derivatives of formula (I) and their preparation. The compounds are useful synthetic intermediates for the synthesis of HIV protease inhibitors and oligopeptide mimetics.