CAS: 7004-98-0; 3-Methoxyestra-1,3,5(10)-Triene-16.α.,17.α.-Diol
该化合物是一种主要用于激素替代疗法和某些妇科病的合成雌激素,是丝特拉多醇的衍生物,并展示了类似的生物活动,对雌激激素受体有约束力并影响基因表达;其特点是能够促进女性生殖组织的发展和维护,以及其在调节月经周期方面的作用;该化合物通常以各种形式施用,包括口服药片或注射,取决于治疗应用;其药理效应可包括减轻更年期症状,预防骨质疏松症和某些对激素敏感的癌症的管理;然而,它与其他雌激剂一样,也可能具有副作用,包括血栓症事件风险增加,以及心血管健康可能受到的影响;与任何荷尔蒙疗法一样,保健专业人员的仔细考虑和监测对于在尽可能降低风险的同时优化惠益至关重要.
- 英文名称3-Methoxyestra-1,3,5(10)-Triene-16.α.,17.α.-Diol
- 中文名称表美雌醇
- IUPAC名称(8R,9S,13S,14S,16R,17S)-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-16,17-diol
- 其它别名Estra-1,3,5(10)-triene-16a,17a-diol, 3-methoxy- (6CI,7CI,8CI); 16a,17a-Dihydroxy-3-methoxyestra-1,3,5(10)-triene; 3-Methoxy)estra-1,3,5(10)-triene-16a,17a-diol; 3-Methoxy-17-epiestriol; Epimestrol; Stimovul
- CAS编号7004-98-0
- MFCD编号:MFCD00198991
- EINECS号:230-278-0
- FDA UNII编号:7IVE3SDZ38
- 分子式:C19H26O3分子量:302.41
- 产品CID: 1694488
- 产品分类有机原料 → 脂质和类脂质分子 → 类固醇和类固醇衍生物
物理性质
MSDS等安全信息
上下游产品
CAS号81163-66-8 3-Methoxy-oestr... | CAS号28336-32-5 16α,17α-Epoxy-3... | CAS号55821-45-9 16α-Brom-3-meth... | CAS号81163-63-5 16β-Brom-17α-et...合成工艺路线路线简述
📜16β-Brom-17α-Ethylaminocarbonyloxy-Oestra-1,3,5(10)-Trien-3-Methylether置于乙醇,Potassium Carbonate体系中,用 乙醇,水 作为反应溶剂,化学反应 11.0H,反应生成 雌三醇甲醚
参考文献:Ponsold,K.; Grosse,P.,Journal Fur Praktische Chemie (Leipzig 1954),1981,Vol. 323,# 5,P. 801-818
标题:Ponsold,K.; Grosse,P.,Journal Fur Praktische Chemie (Leipzig 1954),1981,Vol. 323,# 5,P. 801-818
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2905122000-异丙醇
2905310000-1,2-乙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Genazzani AR, Petraglia F, Mercuri N, Brilli G, Genazzani AD, Bergamaschi M, DeRamundo BM, Volpe A. Effect of steroid hormones and antihormones on hypothalamic beta-endorphin concentrations in intact and castrated female rats. J Endocrinol Invest. 1990 Feb;13(2):91-6. doi: 10.1007/BF03349515. 54(3):115-23. Spanish. 44(1):17-20. Spanish. 115(8-9):869-77. Serbian. 26(5):589-97. doi: 10.1016/0022-4731(87)90012-4. 45(4):449-52. 18(1):39-43. 46(7):444-9. German. doi: 10.1055/s-2008-1026661. 38(5):401-6. Italian. 45(7):459-61. German. doi: 10.1055/s-2008-1036352. 56(5-6):387-8. Polish. 14(7):899-913. French. 15(3):175-7. 74(19):1097-126. Italian. 35(4):239-46. Italian. 54(4):281-4. Polish. 9(1):59-69. doi: 10.1111/j.1447-0756.1983.tb00605.x. 6(2):133-40. 33(6):520-7. Italian. 103(9):502-14. German.
合成参考文献
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
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